Accuracy of Self-Reported HIV Status Among African Men and Transgender Women Who Have Sex with Men Who were Screened for Participation in a Research Study: HPTN 075

Jessica M. Fogel; Theodorus Sandfort; Yinfeng Zhang; Xu Guo; William Clarke; Autumn Breaud; Vanessa Cummings; Erica L. Hamilton; Arthur Ogendo; Noel Kayange; Ravindre Panchia; Karen Dominguez; Ying Q. Chen; Susan H. Eshleman

doi:10.1007/s10461-018-2231-1

Accuracy of Self-Reported HIV Status Among African Men and Transgender Women Who Have Sex with Men Who were Screened for Participation in a Research Study: HPTN 075

Jessica M. Fogel, Theodorus Sandfort, Yinfeng Zhang, Xu Guo, William Clarke, Autumn Breaud, Vanessa Cummings, Erica L. Hamilton, Arthur Ogendo, Noel Kayange, Ravindre Panchia, Karen Dominguez, Ying Q. Chen, Susan H. Eshleman

School of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Some HIV-infected individuals in research studies may choose not to disclose knowledge of their HIV status to study staff. We evaluated the accuracy of self-reported HIV status among African men and transgender women who have sex with men and who were screened for a research study. Sixty-seven of 183 HIV-infected participants reported a prior HIV diagnosis. Samples from the remaining 116 participants were tested for antiretroviral (ARV) drugs. Thirty-six of the 116 participants had ARV drugs detected, indicating that they were on antiretroviral treatment; these participants were classified as previously diagnosed based on ARV drug testing. Among participants classified as previously diagnosed, disclosure of a prior HIV diagnosis varied among study sites (p = 0.006) and was more common among those who reported having sex with men only (p = 0.002). ARV drug testing in addition to self-report improves the accuracy for identifying individuals with a prior HIV diagnosis.

Original language	English (US)
Pages (from-to)	289-294
Number of pages	6
Journal	AIDS and behavior
Volume	23
Issue number	1
DOIs	https://doi.org/10.1007/s10461-018-2231-1
State	Published - Jan 15 2019

Keywords

ART
Africa
HIV
MSM
Self-report
Transgender women

ASJC Scopus subject areas

Social Psychology
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1007/s10461-018-2231-1

Cite this

Fogel, J. M., Sandfort, T., Zhang, Y., Guo, X., Clarke, W., Breaud, A., Cummings, V., Hamilton, E. L., Ogendo, A., Kayange, N., Panchia, R., Dominguez, K., Chen, Y. Q., & Eshleman, S. H. (2019). Accuracy of Self-Reported HIV Status Among African Men and Transgender Women Who Have Sex with Men Who were Screened for Participation in a Research Study: HPTN 075. AIDS and behavior, 23(1), 289-294. https://doi.org/10.1007/s10461-018-2231-1

Fogel, JM, Sandfort, T, Zhang, Y, Guo, X, Clarke, W, Breaud, A, Cummings, V, Hamilton, EL, Ogendo, A, Kayange, N, Panchia, R, Dominguez, K, Chen, YQ & Eshleman, SH 2019, 'Accuracy of Self-Reported HIV Status Among African Men and Transgender Women Who Have Sex with Men Who were Screened for Participation in a Research Study: HPTN 075', AIDS and behavior, vol. 23, no. 1, pp. 289-294. https://doi.org/10.1007/s10461-018-2231-1

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title = "Accuracy of Self-Reported HIV Status Among African Men and Transgender Women Who Have Sex with Men Who were Screened for Participation in a Research Study: HPTN 075",

abstract = "Some HIV-infected individuals in research studies may choose not to disclose knowledge of their HIV status to study staff. We evaluated the accuracy of self-reported HIV status among African men and transgender women who have sex with men and who were screened for a research study. Sixty-seven of 183 HIV-infected participants reported a prior HIV diagnosis. Samples from the remaining 116 participants were tested for antiretroviral (ARV) drugs. Thirty-six of the 116 participants had ARV drugs detected, indicating that they were on antiretroviral treatment; these participants were classified as previously diagnosed based on ARV drug testing. Among participants classified as previously diagnosed, disclosure of a prior HIV diagnosis varied among study sites (p = 0.006) and was more common among those who reported having sex with men only (p = 0.002). ARV drug testing in addition to self-report improves the accuracy for identifying individuals with a prior HIV diagnosis.",

keywords = "ART, Africa, HIV, MSM, Self-report, Transgender women",

author = "Fogel, {Jessica M.} and Theodorus Sandfort and Yinfeng Zhang and Xu Guo and William Clarke and Autumn Breaud and Vanessa Cummings and Hamilton, {Erica L.} and Arthur Ogendo and Noel Kayange and Ravindre Panchia and Karen Dominguez and Chen, {Ying Q.} and Eshleman, {Susan H.}",

note = "Funding Information: participants for providing the samples and data used in this study. We also thank the laboratory staff who helped with sample management and testing. This work was supported by the grants from the Division of AIDS of the U.S. National Institute of Allergy and Infectious Diseases (NIAID), the National Institute of Mental Health (NIMH), and the Office of AIDS Research of the U.S. National Institutes of Health (NIH) [UM1-AI068613 (Eshleman); UM1-AI068617 (Donnell); and UM1-AI068619 (Cohen/El-Sadr)]. Dr. Sandfort also received support from an NIMH Grant, to the HIV Center for Clinical and Behavioral Research, P30-MH42520 (Remien). Publisher Copyright: {\textcopyright} 2018, Springer Science+Business Media, LLC, part of Springer Nature.",

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doi = "10.1007/s10461-018-2231-1",

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AU - Fogel, Jessica M.

AU - Sandfort, Theodorus

AU - Zhang, Yinfeng

AU - Guo, Xu

AU - Clarke, William

AU - Breaud, Autumn

AU - Cummings, Vanessa

AU - Hamilton, Erica L.

AU - Ogendo, Arthur

AU - Kayange, Noel

AU - Panchia, Ravindre

AU - Dominguez, Karen

AU - Chen, Ying Q.

AU - Eshleman, Susan H.

N1 - Funding Information: participants for providing the samples and data used in this study. We also thank the laboratory staff who helped with sample management and testing. This work was supported by the grants from the Division of AIDS of the U.S. National Institute of Allergy and Infectious Diseases (NIAID), the National Institute of Mental Health (NIMH), and the Office of AIDS Research of the U.S. National Institutes of Health (NIH) [UM1-AI068613 (Eshleman); UM1-AI068617 (Donnell); and UM1-AI068619 (Cohen/El-Sadr)]. Dr. Sandfort also received support from an NIMH Grant, to the HIV Center for Clinical and Behavioral Research, P30-MH42520 (Remien). Publisher Copyright: © 2018, Springer Science+Business Media, LLC, part of Springer Nature.

PY - 2019/1/15

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N2 - Some HIV-infected individuals in research studies may choose not to disclose knowledge of their HIV status to study staff. We evaluated the accuracy of self-reported HIV status among African men and transgender women who have sex with men and who were screened for a research study. Sixty-seven of 183 HIV-infected participants reported a prior HIV diagnosis. Samples from the remaining 116 participants were tested for antiretroviral (ARV) drugs. Thirty-six of the 116 participants had ARV drugs detected, indicating that they were on antiretroviral treatment; these participants were classified as previously diagnosed based on ARV drug testing. Among participants classified as previously diagnosed, disclosure of a prior HIV diagnosis varied among study sites (p = 0.006) and was more common among those who reported having sex with men only (p = 0.002). ARV drug testing in addition to self-report improves the accuracy for identifying individuals with a prior HIV diagnosis.

AB - Some HIV-infected individuals in research studies may choose not to disclose knowledge of their HIV status to study staff. We evaluated the accuracy of self-reported HIV status among African men and transgender women who have sex with men and who were screened for a research study. Sixty-seven of 183 HIV-infected participants reported a prior HIV diagnosis. Samples from the remaining 116 participants were tested for antiretroviral (ARV) drugs. Thirty-six of the 116 participants had ARV drugs detected, indicating that they were on antiretroviral treatment; these participants were classified as previously diagnosed based on ARV drug testing. Among participants classified as previously diagnosed, disclosure of a prior HIV diagnosis varied among study sites (p = 0.006) and was more common among those who reported having sex with men only (p = 0.002). ARV drug testing in addition to self-report improves the accuracy for identifying individuals with a prior HIV diagnosis.

KW - ART

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KW - HIV

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KW - Self-report

KW - Transgender women

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Accuracy of Self-Reported HIV Status Among African Men and Transgender Women Who Have Sex with Men Who were Screened for Participation in a Research Study: HPTN 075

Abstract

Keywords

ASJC Scopus subject areas

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