Among several tyrosine-protein kinases, only v-abl could abrogate interleukin 3 dependence of a lymphoblastoid cell line; v-src and v-fps proteins gave partial or no interleukin 3 independence, respectively. Lymphokine independence was achieved via a nonautocrine mechanism. Direct involvement of c-myc in this process was not evident.
|Original language||English (US)|
|Number of pages||3|
|Journal||Molecular and Cellular Biology|
|State||Published - Nov 1986|
ASJC Scopus subject areas
- Cell Biology
- Molecular Biology