Ab-interno sclerostomy using a goniodiathermy instrument

S. V L Brown, E. J. Higginbotham, E. O. Griffin, X. Zou, D. Edward

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


We describe the use of a new instrument designed to create a simultaneous goniopuncture with diathermy using an ab-interno technique. The goniodiathermy ab-interno procedure was first performed on three eyes of three cynomolgus monkeys. Intraocular pressure (IOP) assessment and histologic examination were performed over a 10-day period. A functioning filtration bleb with a patent sclerostomy was achieved in all of the experimental eyes. A pilot study involving four eyes of four glaucoma patients also was performed. Of these four, successful long-term functioning filtration areas with adequate lowering of IOP were achieved in only two. The remaining two required further surgical intervention. Although combining goniopuncture and diathermy into a one-step ab-interno procedure proved successful in the primates studied, the preliminary use of this new instrument as a method of creating a filter in humans raises questions regarding its clinical usefulness.

Original languageEnglish (US)
Pages (from-to)112-116
Number of pages5
JournalOphthalmic Surgery
Issue number2
StatePublished - 1994
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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