A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM)

Jonathan S. Ward; Jason M. Lynam; James W.B. Moir; David E. Sanin; Adrian P. Mountford; Ian J.S. Fairlamb

doi:10.1039/c2dt31588b

A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM)

Jonathan S. Ward
, Jason M. Lynam
, James W.B. Moir
, David E. Sanin
, Adrian P. Mountford
, Ian J.S. Fairlamb

Research output: Contribution to journal › Article › peer-review

Abstract

A new class of photochemically-activated CO-releasing molecule (photo-CO-RM), based on a Mn(CO)₄(C^N) system, is reported in this study. Three CO molecules are released per CO-RM molecule. Complex 3 is a fast releaser, thermally stable in the dark and a viable therapeutic agent.

Original language	English (US)
Pages (from-to)	10514-10517
Number of pages	4
Journal	Dalton Transactions
Volume	41
Issue number	35
DOIs	https://doi.org/10.1039/c2dt31588b
State	Published - Sep 21 2012
Externally published	Yes

ASJC Scopus subject areas

Inorganic Chemistry

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10.1039/c2dt31588b

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abstract = "A new class of photochemically-activated CO-releasing molecule (photo-CO-RM), based on a Mn(CO)4(C\textasciicircum{}N) system, is reported in this study. Three CO molecules are released per CO-RM molecule. Complex 3 is a fast releaser, thermally stable in the dark and a viable therapeutic agent.",

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AU - Ward, Jonathan S.

AU - Lynam, Jason M.

AU - Moir, James W.B.

AU - Sanin, David E.

AU - Mountford, Adrian P.

AU - Fairlamb, Ian J.S.

PY - 2012/9/21

Y1 - 2012/9/21

N2 - A new class of photochemically-activated CO-releasing molecule (photo-CO-RM), based on a Mn(CO)4(C^N) system, is reported in this study. Three CO molecules are released per CO-RM molecule. Complex 3 is a fast releaser, thermally stable in the dark and a viable therapeutic agent.

AB - A new class of photochemically-activated CO-releasing molecule (photo-CO-RM), based on a Mn(CO)4(C^N) system, is reported in this study. Three CO molecules are released per CO-RM molecule. Complex 3 is a fast releaser, thermally stable in the dark and a viable therapeutic agent.

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M3 - Article

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JO - Dalton Transactions

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A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM)

Abstract

ASJC Scopus subject areas

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