TY - JOUR
T1 - A systematic approach to the diagnosis and treatment of chronic conjunctivitis
AU - Rapoza, P. A.
AU - Quinn, T. C.
AU - Terry, A. C.
AU - Gottsch, J. D.
AU - Kiessling, L. A.
AU - Taylor, H. R.
N1 - Funding Information:
From the Department of Ophthalmology, the University of Wisconsin-Madison, Madison, Wisconsin (Dr. Rapoza); the Dana Center for Preventive Ophthalmology (Drs. Kiessling and Taylor) and the Cornea Service (Drs. Terry, Gottsch, and Taylor), Wilmer Ophthalmological Institute, and the Department of Medicine (Dr. Quinn), Johns Hopkins University, Baltimore, Maryland; and the National Institutes of Health, Bethesda, Maryland (Dr. Quinn). This study was supported in part by grants EY03324 and EY01765 from the National Institutes of Health, Bethesda, Maryland, and by a grant from the Syva Company, Palo Alto, California.
PY - 1990
Y1 - 1990
N2 - In 58 patients with chronic conjunctivitis of greater than two weeks' duration, examination included obtaining an ocular and general medical history and performing a complete ophthalmic examination of the external eye. Conjunctival smears were obtained for Gram and Giemsa staining, direct immunofluorescent monoclonal antibody staining for Chlamydia trachomatis and herpes simplex virus, and chlamydial culture. Cultures for bacteria and viruses were obtained in 33 patients. The cause of the chronic conjunctivitis based on clinical and laboratory criteria was established in 40 of 58 (69%) patients: chlamydia, 11 (19%); virus eight (14%); irritant, six (10%); allergen, four (7%); contact lens, four (7%); bacteria, four (7%); acne rosacea, two (3%); and floppy eyelid syndrome, one (2%). In 18 of 58 (31%) patients, no specific cause was detected. We recommend a systematic approach in the investigation of chronic conjunctivitis. Direct immunofluorescent monoclonal antibody staining is an effective and rapid technique for detecting chronic chlamydia conjunctivitis.
AB - In 58 patients with chronic conjunctivitis of greater than two weeks' duration, examination included obtaining an ocular and general medical history and performing a complete ophthalmic examination of the external eye. Conjunctival smears were obtained for Gram and Giemsa staining, direct immunofluorescent monoclonal antibody staining for Chlamydia trachomatis and herpes simplex virus, and chlamydial culture. Cultures for bacteria and viruses were obtained in 33 patients. The cause of the chronic conjunctivitis based on clinical and laboratory criteria was established in 40 of 58 (69%) patients: chlamydia, 11 (19%); virus eight (14%); irritant, six (10%); allergen, four (7%); contact lens, four (7%); bacteria, four (7%); acne rosacea, two (3%); and floppy eyelid syndrome, one (2%). In 18 of 58 (31%) patients, no specific cause was detected. We recommend a systematic approach in the investigation of chronic conjunctivitis. Direct immunofluorescent monoclonal antibody staining is an effective and rapid technique for detecting chronic chlamydia conjunctivitis.
UR - http://www.scopus.com/inward/record.url?scp=0025190429&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025190429&partnerID=8YFLogxK
U2 - 10.1016/S0002-9394(14)75977-X
DO - 10.1016/S0002-9394(14)75977-X
M3 - Article
C2 - 2154106
AN - SCOPUS:0025190429
SN - 0002-9394
VL - 109
SP - 138
EP - 142
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 2
ER -