TY - GEN
T1 - A super-resolution feasibility study in small animal SPECT imaging
AU - Villena, José L.
AU - Lage, Eduardo
AU - De Carlos, Alvaro
AU - Tapias, Gustavo
AU - Sisniega, Alejandro
AU - Vaquero, Juan José
AU - Desco, Manuel
PY - 2008
Y1 - 2008
N2 - Lack of spatial resolution is a major drawback in small-animal SPECT imaging, particularly when parallel hole collimators are employed. This work evaluates the feasibility of enhancing the spatial resolution of a small-animal SPECT scanner by applying an approach based on a super-resolution technique combined with dedicated hardware. The detectors are based on PS-PMTs (Hamamatsu, H8500), NaI(TI) crystal arrays and parallel hole collimators. The system enables the mechanical shifting of the gamma-cameras and the object under study during the acquisition in steps smaller than the detector intrinsic sampling pitch. This fact allows using a super-resolution technique without the necessity of blind movement estimators between projections. In the absence of noise the algorithm converged to the original image, and with real noisy data it achieved improvements in resolution between 28% (tomographic) and 42% (planar) in phantom studies.
AB - Lack of spatial resolution is a major drawback in small-animal SPECT imaging, particularly when parallel hole collimators are employed. This work evaluates the feasibility of enhancing the spatial resolution of a small-animal SPECT scanner by applying an approach based on a super-resolution technique combined with dedicated hardware. The detectors are based on PS-PMTs (Hamamatsu, H8500), NaI(TI) crystal arrays and parallel hole collimators. The system enables the mechanical shifting of the gamma-cameras and the object under study during the acquisition in steps smaller than the detector intrinsic sampling pitch. This fact allows using a super-resolution technique without the necessity of blind movement estimators between projections. In the absence of noise the algorithm converged to the original image, and with real noisy data it achieved improvements in resolution between 28% (tomographic) and 42% (planar) in phantom studies.
UR - http://www.scopus.com/inward/record.url?scp=67649191612&partnerID=8YFLogxK
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U2 - 10.1109/NSSMIC.2008.4774306
DO - 10.1109/NSSMIC.2008.4774306
M3 - Conference contribution
AN - SCOPUS:67649191612
SN - 9781424427154
T3 - IEEE Nuclear Science Symposium Conference Record
SP - 4755
EP - 4759
BT - 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
T2 - 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Y2 - 19 October 2008 through 25 October 2008
ER -