A summary of results of the Dietary Intervention Study in Children (DISC): lessons learned.

Linda Van Horn, Eva Obarzanek, Bruce A. Barton, Victor J. Stevens, Peter O. Kwiterovich, Norman L. Lasser, Alan M. Robson, Frank A. Franklin, Ronald M. Lauer, Sue Y.S. Kimm, Joanne F. Dorgan, Merwyn R. Greenlick

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Prevention of cardiovascular disease must begin in childhood, preferably before risk factors develop. Elevated low-density lipoprotein cholesterol levels in children are likely to track over time and become high-risk levels in adults. The Dietary Intervention Study in Children (DISC) was a multicenter, collaborative randomized trial in pre-adolescent children designed to test the efficacy and safety of a dietary intervention to lower saturated fat and cholesterol intake among growing children with elevated low-density lipoprotein cholesterol. Numerous DISC results, which include findings on lipids-lipoproteins, genetics, and nutrient adequacy, as well as descriptions of the behavioral intervention strategies, have been reported. A summary of practical findings and their potential clinical applications have not previously been published. Highlights of key lessons learned from DISC and translational applications of potential interest to nurses and other health care providers are presented.

Original languageEnglish (US)
Pages (from-to)28-41
Number of pages14
JournalProgress in cardiovascular nursing
Issue number1
StatePublished - 2003
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Nursing (miscellaneous)


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