Abstract
A simple mathematical model of the hemodynamic effects of a discrete proximal coronary artery obstruction is presented. The model demonstrates that resting myocardial flow demands fail to be met when the vessel diameter is decreased by 75% or greater. More strikingly, it shows that the maximum flow obtainable for increased myocardial oxygen demand begins to fall significantly with a lesion causing a 40 to 50% obstruction. The implications of these findings in relation to stress-induced angina are discussed.
Original language | English (US) |
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Pages (from-to) | 309-312 |
Number of pages | 4 |
Journal | Annals of Thoracic Surgery |
Volume | 19 |
Issue number | 3 |
DOIs | |
State | Published - 1975 |
ASJC Scopus subject areas
- Surgery
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine