Abstract
A short, stereoselective, and a common approach for the synthesis of 4,5-disubstituted δ-lactones simplactone B and its analogue using Evans protocol is described.
Original language | English (US) |
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Pages (from-to) | 2085-2086 |
Number of pages | 2 |
Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 15 |
Issue number | 8 |
DOIs | |
State | Published - Apr 15 2005 |
Externally published | Yes |
Keywords
- Chiral auxiliary
- Cytotoxic activity
- Evans-asymmetric aldol methodology
- Tempo oxidation
- δ-Lactones
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmaceutical Science
- Drug Discovery
- Clinical Biochemistry
- Organic Chemistry