A set theoretical approach to immunotaxonomy: Analysis of species comparisons in modified ouchterlony plates

G. William Moore; Morris Goodman

doi:10.1007/BF02476695

A set theoretical approach to immunotaxonomy: Analysis of species comparisons in modified ouchterlony plates

G. William Moore, Morris Goodman

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21 Scopus citations

Abstract

The precipitin spurs formed in Ochterlony comparisons of corresponding antigens in different species can be defined using the notation of set theory. A computer program based on this set theory definition can then be applied to Ouchterlony data so as to list the various species employed in the comparisons in order of increasing divergence, from an homologous species. Such a computer program concisely captured conclusions, previously drawn in a more discursive manner, from data obtained with chicken and rabbit antisera to purified human serum proteins and produced results highly correlated with those of the more quantitative method of micro-complement fixation.

Original language	English (US)
Pages (from-to)	279-289
Number of pages	11
Journal	The Bulletin of Mathematical Biophysics
Volume	30
Issue number	2
DOIs	https://doi.org/10.1007/BF02476695
State	Published - Jun 1968
Externally published	Yes

ASJC Scopus subject areas

General Agricultural and Biological Sciences
General Medicine

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title = "A set theoretical approach to immunotaxonomy: Analysis of species comparisons in modified ouchterlony plates",

abstract = "The precipitin spurs formed in Ochterlony comparisons of corresponding antigens in different species can be defined using the notation of set theory. A computer program based on this set theory definition can then be applied to Ouchterlony data so as to list the various species employed in the comparisons in order of increasing divergence, from an homologous species. Such a computer program concisely captured conclusions, previously drawn in a more discursive manner, from data obtained with chicken and rabbit antisera to purified human serum proteins and produced results highly correlated with those of the more quantitative method of micro-complement fixation.",

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year = "1968",

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AU - Goodman, Morris

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AB - The precipitin spurs formed in Ochterlony comparisons of corresponding antigens in different species can be defined using the notation of set theory. A computer program based on this set theory definition can then be applied to Ouchterlony data so as to list the various species employed in the comparisons in order of increasing divergence, from an homologous species. Such a computer program concisely captured conclusions, previously drawn in a more discursive manner, from data obtained with chicken and rabbit antisera to purified human serum proteins and produced results highly correlated with those of the more quantitative method of micro-complement fixation.

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A set theoretical approach to immunotaxonomy: Analysis of species comparisons in modified ouchterlony plates

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