A robust spike and wave algorithm for detecting seizures in a genetic absence seizure model.

Petros Xanthopoulos; Chang Chia Liu; Jicong Zhang; Eric R. Miller; S. P. Nair; Basim M. Uthman; Kevin Kelly; Panos M. Pardalos

A robust spike and wave algorithm for detecting seizures in a genetic absence seizure model.

Petros Xanthopoulos, Chang Chia Liu, Jicong Zhang, Eric R. Miller, S. P. Nair, Basim M. Uthman, Kevin Kelly, Panos M. Pardalos

Research output: Contribution to journal › Article › peer-review

Abstract

Animal Models are used extensively in basic epilepsy research. In many studies, there is a need to accurately score and quantify all epileptic spike and wave discharges (SWDs) as captured by electroencephalographic (EEG) recordings. Manual scoring of long term EEG recordings is a time-consuming and tedious task that requires inordinate amount of time of laboratory personnel and an experienced electroencephalographer. In this paper, we adapt a SWD detection algorithm, originally proposed by the authors for absence (petit mal) seizure detection in humans, to detect SWDs appearing in EEG recordings of Fischer 334 rats. The algorithm is robust with respect to the threshold parameters. Results are compared to manual scoring and the effect of different threshold parameters is discussed.

Original language	English (US)
Pages (from-to)	2184-2187
Number of pages	4
Journal	Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
State	Published - 2009
Externally published	Yes

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Signal Processing
Biomedical Engineering
Health Informatics

Cite this

Xanthopoulos, P., Liu, C. C., Zhang, J., Miller, E. R., Nair, S. P., Uthman, B. M., Kelly, K., & Pardalos, P. M. (2009). A robust spike and wave algorithm for detecting seizures in a genetic absence seizure model. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2184-2187.

A robust spike and wave algorithm for detecting seizures in a genetic absence seizure model. / Xanthopoulos, Petros; Liu, Chang Chia; Zhang, Jicong et al.
In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2009, p. 2184-2187.

Research output: Contribution to journal › Article › peer-review

Xanthopoulos, P, Liu, CC, Zhang, J, Miller, ER, Nair, SP, Uthman, BM, Kelly, K & Pardalos, PM 2009, 'A robust spike and wave algorithm for detecting seizures in a genetic absence seizure model.', Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 2184-2187.

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AU - Uthman, Basim M.

AU - Kelly, Kevin

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A robust spike and wave algorithm for detecting seizures in a genetic absence seizure model.

Abstract

ASJC Scopus subject areas

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