A review of population-based retinal studies of the microvascular contribution to cerebrovascular diseases

A. Richey Sharrett

doi:10.1080/09286580701396712

A review of population-based retinal studies of the microvascular contribution to cerebrovascular diseases

A. Richey Sharrett

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Studies of retinal signs, as non-invasively obtained markers of microvasculature, may help to assess the microvascular contribution to ischemic cardiovascular diseases, particularly those affecting the brain. Changes in the retinal arterioles are particularly pertinent to ischemia, and several studies show their associations with MRI-assessed cerebral lacunar infarcts and white matter changes. Data are too sparse to judge the contribution to cerebral atrophy or cognitive impairment. Confounding and imprecise measurements may cloud the results of this research. A paired comparison method is proposed for avoiding some of these issues.

Original language	English (US)
Pages (from-to)	238-242
Number of pages	5
Journal	Ophthalmic Epidemiology
Volume	14
Issue number	4
DOIs	https://doi.org/10.1080/09286580701396712
State	Published - Jul 2007
Externally published	Yes

Keywords

Cerebrovascular disease
Cognitive impairment
Microvasculature
Retinal vessels

ASJC Scopus subject areas

Epidemiology
Ophthalmology

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10.1080/09286580701396712

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abstract = "Studies of retinal signs, as non-invasively obtained markers of microvasculature, may help to assess the microvascular contribution to ischemic cardiovascular diseases, particularly those affecting the brain. Changes in the retinal arterioles are particularly pertinent to ischemia, and several studies show their associations with MRI-assessed cerebral lacunar infarcts and white matter changes. Data are too sparse to judge the contribution to cerebral atrophy or cognitive impairment. Confounding and imprecise measurements may cloud the results of this research. A paired comparison method is proposed for avoiding some of these issues.",

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AB - Studies of retinal signs, as non-invasively obtained markers of microvasculature, may help to assess the microvascular contribution to ischemic cardiovascular diseases, particularly those affecting the brain. Changes in the retinal arterioles are particularly pertinent to ischemia, and several studies show their associations with MRI-assessed cerebral lacunar infarcts and white matter changes. Data are too sparse to judge the contribution to cerebral atrophy or cognitive impairment. Confounding and imprecise measurements may cloud the results of this research. A paired comparison method is proposed for avoiding some of these issues.

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KW - Retinal vessels

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A review of population-based retinal studies of the microvascular contribution to cerebrovascular diseases

Abstract

Keywords

ASJC Scopus subject areas

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