A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: The treatment of early aggressive rheumatoid arthritis trial

Larry W. Moreland, James R. O'Dell, Harold E. Paulus, Jeffrey R. Curtis, Joan M. Bathon, E. William St.clair, S. Louis Bridges, Jie Zhang, Theresa McVie, George Howard, Désirée Van Der Heijde, Stacey S. Cofield

Research output: Contribution to journalArticlepeer-review

277 Scopus citations

Abstract

Objective To assess whether it is better to intensively treat all patients with early rheumatoid arthritis (RA) using combinations of drugs or to reserve this approach for patients who do not have an appropriate response (as determined by a Disease Activity Score in 28 joints using the erythrocyte sedimentation rate [DAS28-ESR] of

Original languageEnglish (US)
Pages (from-to)2824-2835
Number of pages12
JournalArthritis and Rheumatism
Volume64
Issue number9
DOIs
StatePublished - Sep 2012
Externally publishedYes

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Rheumatology
  • Pharmacology (medical)

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