@inproceedings{ab80837b10804e1cbcad117478686852,
title = "A quantum dot based nanoassay for quantifying gene copy number with ultrahigh resolution",
abstract = "DNA CNV is fundamental to study molecular etiology of human diseases such as developmental disorder and cancer [1, 2]. The current CNV detection relies on hybridization or semi quantitative PCR whose technical limitations compromise the accuracy. In addition, current techniques are not able to reliably differentiate less than a twofold change in CNV [3,4]. This paper presents a novel gene copy number variation (CNV) detection method named quantum dot (QD) Electrophoretic Mobility Shift Assay (QEMSA). This nanoassay demonstrates a remarkable resolution, capable of distinguishing a 1.1-fold (∼9%) difference in target copy number.",
keywords = "Copy number variation, Nanoassay, Quantum dot, Ultrahigh resolution",
author = "Yi Zhang and Shih, {Ie Ming} and Wang, {Tian Li} and Wang, {Tza Huei}",
year = "2010",
language = "English (US)",
isbn = "9781618390622",
series = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010",
pages = "1154--1156",
booktitle = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010",
note = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 ; Conference date: 03-10-2010 Through 07-10-2010",
}