Abstract
A prospective study of motor recovery was undertaken in a patient scheduled to undergo multiple subpial transections (MST) of right sensorimotor cortex. Pre-transection, functional MRI (fMRI) and cortical stimulation mapping confirmed left hand motor control within right primary motor cortex. Immediately post-transection, behavioral testing demonstrated preserved strength bilaterally but decreased dexterity in the left hand. Seven weeks post-transection, dexterity returned to normal and left hand finger tapping corresponded with multiple bilateral foci of fMRI activation. At 16 weeks, fMRI activation returned to pre-transection levels. These data indicate that cortical injury due to MST resulted in the temporary recruitment of distant cortical sites which presumably subserved normal motor function during recovery.
Original language | English (US) |
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Pages (from-to) | 665-669 |
Number of pages | 5 |
Journal | Neuroreport |
Volume | 13 |
Issue number | 5 |
DOIs | |
State | Published - Apr 16 2002 |
Keywords
- Cortex
- Cortical stimulation
- Epilepsy
- Human
- Motor
- Plasticity
- Recovery
- Reorganization
- Surgery
- fMRI
ASJC Scopus subject areas
- Neuroscience(all)