Original language | English (US) |
---|---|
Pages (from-to) | 421-424 |
Number of pages | 4 |
Journal | Kidney international |
Volume | 103 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2023 |
Keywords
- chronic kidney disease
- kidney function
- polygenic score
ASJC Scopus subject areas
- Nephrology
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In: Kidney international, Vol. 103, No. 2, 02.2023, p. 421-424.
Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - A polygenic score for reduced kidney function and adverse outcomes in a cohort with chronic kidney disease
AU - GCKD Investigators
AU - Steinbrenner, Inga
AU - Yu, Zhi
AU - Jin, Jin
AU - Schultheiss, Ulla T.
AU - Kotsis, Fruzsina
AU - Grams, Morgan E.
AU - Coresh, Josef
AU - Wuttke, Matthias
AU - Kronenberg, Florian
AU - Eckardt, Kai Uwe
AU - Chatterjee, Nilanjan
AU - Sekula, Peggy
AU - Köttgen, Anna
N1 - Funding Information: The German Chronic Kidney Disease (GCKD) study was funded by grants from the Federal Ministry of Education and Research (BMBF) grant 01ER0804 and the KfH Foundation for Preventive Medicine and corporate sponsors (http://www.gckd.org). Genotyping in GCKD study was supported by Bayer Pharma AG. We are grateful for the willingness of the patients to participate in the GCKD study. The enormous effort of the study personnel of the various regional centers is highly appreciated. We thank the large number of nephrologists who provide routine care for the patients and collaborate with the GCKD study. The GCKD Investigators are listed in the Supplementary Material. The work of AK, MW, and PS was supported by German Research Foundation Project identifier 431984000–SFB 1453. The work of AK was also supported by the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement no. 860977. The work of JJ was supported by a grant of the National Human Genome Research Institute (grant K99HG012223). The work of NC and JJ was supported by a grant of the National Human Genome Research Institute (grant R01HG010480). The work of ZY was supported by a grant of the National Heart, Lung, and Blood Institute (grant 5T32HL007604-37). The work of UTS was supported by the BMBF within the framework of the e:Med research and funding concept (grant 01ZX1912B). This research has been conducted using the UK Biobank Resource under Application Number 17712.
PY - 2023/2
Y1 - 2023/2
KW - chronic kidney disease
KW - kidney function
KW - polygenic score
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UR - http://www.scopus.com/inward/citedby.url?scp=85144337737&partnerID=8YFLogxK
U2 - 10.1016/j.kint.2022.11.013
DO - 10.1016/j.kint.2022.11.013
M3 - Article
C2 - 36481179
AN - SCOPUS:85144337737
SN - 0085-2538
VL - 103
SP - 421
EP - 424
JO - Kidney international
JF - Kidney international
IS - 2
ER -