A PGC1α-mediated transcriptional axis suppresses melanoma metastasis

Biochemistry, Genetics and Molecular Biology

• Metabolic Pathway 100%
• Integrin 100%
• TCF4 100%
• ID2 100%
• Transcription 50%
• Downregulation 50%
• Oxidative Stress 50%
• Tumor Progression 50%
• Drug Sensitivity 50%
• Mitochondrial Biogenesis 50%
• Reprogramming 50%
• Energy Transfer 50%
• Bioenergy 50%
• Vemurafenib 50%
• Transcription Factor 4 50%

Keyphrases

• Melanoma Metastasis 100%
• PGC-1 100%
• Metastasis 50%
• Transcription Factor 4 (TCF4) 30%
• Melanoma 20%
• Melanoma Cells 20%
• Integrin 20%
• Transcription Factor 10%
• Transcriptional Repressor 10%
• Human Melanoma 10%
• Rapid Progression 10%
• Oxidative Stress 10%
• Vemurafenib 10%
• Metastatic Melanoma 10%
• Therapeutic Potential 10%
• Cytostatic Effect 10%
• Metabolism 10%
• Drug Sensitivity 10%
• Mitochondrial Biogenesis 10%
• Direct Regulation 10%
• New Therapeutics 10%
• Transcriptional Program 10%
• Metastatic Process 10%
• Skin Cancer 10%
• Tumor Progression 10%
• Reconstitution 10%
• Mitochondrial Energetics 10%
• BRAF V600E 10%
• Bioenergetic Metabolism 10%
• Curb 10%
• Metastasis-related Genes 10%
• Metabolic Regulation 10%
• Regulatory Circuit 10%
• Metabolic Reprogramming 10%
• Vertical Growth 10%
• Energetic Metabolism 10%
• Drug Survival 10%