TY - JOUR
T1 - A paracentric chromosomal inversion associated with repeated early pregnancy wastage
AU - Stetten, G.
AU - Rock, J. A.
PY - 1983
Y1 - 1983
N2 - The causes of recurrent early fetal wastage are largely unknown but have been associated with both uterine malformation and unbalanced chromosomal rearrangements. It is estimated that parental translocations, reciprocal or Robertsonian, account for as many as 5% of all recognized early spontaneous abortions. To date, very few chromosomal inversions have been described in these reports. We recently detected a small paracentric inversion in two generations of a family experiencing multiple spontaneous abortions, 46,XX,inv(7)(p15q22). Interpretation of this finding is complicated by a uterine malformation in the proband.
AB - The causes of recurrent early fetal wastage are largely unknown but have been associated with both uterine malformation and unbalanced chromosomal rearrangements. It is estimated that parental translocations, reciprocal or Robertsonian, account for as many as 5% of all recognized early spontaneous abortions. To date, very few chromosomal inversions have been described in these reports. We recently detected a small paracentric inversion in two generations of a family experiencing multiple spontaneous abortions, 46,XX,inv(7)(p15q22). Interpretation of this finding is complicated by a uterine malformation in the proband.
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U2 - 10.1016/S0015-0282(16)47190-6
DO - 10.1016/S0015-0282(16)47190-6
M3 - Article
C2 - 6683201
AN - SCOPUS:0020526280
SN - 0015-0282
VL - 40
SP - 124
EP - 126
JO - Fertility and sterility
JF - Fertility and sterility
IS - 1
ER -