Abstract
We investigated whether endothelial-dependent arterial constriction during reduced shear can be measured using phase contrast magnetic resonance imaging (PCMRI). A cross-section of the femoral artery was acquired during a 5-minute distal occlusion in 33 subjects. Systolic shear rate and radius were measured from the velocity profile via a best-fit parabola. Systolic shear rate decreased immediately after cuff inflation (404 ± 78 to 233 ± 75 sec -1 p < .0001). Radius decreased at 2 min into inflation (3.52 ± .41 to 3.43 ± .42 mm, p < .0001). In conclusion, arterial constriction during reduced flow can be measured using PCMRI. This new method may add important information toward a comprehensive evaluation of endothelial function.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 615-621 |
| Number of pages | 7 |
| Journal | Journal of Cardiovascular Magnetic Resonance |
| Volume | 7 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2005 |
Keywords
- Blood flow
- Endothelial function
- Magnetic resonance imaging
- Vasoconstriction
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Family Practice
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging
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