A Novel Cyclin Gene (CCNF) in the Region of the Polycystic Kidney Disease Gene (PKD1)

B. Kraus; M. Pohlschmidt; A. L S Leung; G. G. Germino; A. Snarey; M. C. Schneider; S. T. Reeders; A. M. Frischauf

doi:10.1006/geno.1994.1578

A Novel Cyclin Gene (CCNF) in the Region of the Polycystic Kidney Disease Gene (PKD1)

B. Kraus, M. Pohlschmidt, A. L S Leung, G. G. Germino, A. Snarey, M. C. Schneider, S. T. Reeders, A. M. Frischauf

School of Medicine

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

The major locus for autosomal dominant polycystic kidney disease (PKD1) is located in a gene-rich region on chromosome 16p13.3. Recently the identification of the gene responsible for PKD1 has been described. While searching for candidate genes in this region, we isolated a new member of the cyclin family. We have characterized the transcript by sequencing, determination of the exon intron boundaries, and Northern blot analysis. Cyclin F is related to A- and B-type cyclins by sequence, but its function is unknown.

Original language	English (US)
Pages (from-to)	27-33
Number of pages	7
Journal	Genomics
Volume	24
Issue number	1
DOIs	https://doi.org/10.1006/geno.1994.1578
State	Published - Nov 1 1994

ASJC Scopus subject areas

Genetics

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abstract = "The major locus for autosomal dominant polycystic kidney disease (PKD1) is located in a gene-rich region on chromosome 16p13.3. Recently the identification of the gene responsible for PKD1 has been described. While searching for candidate genes in this region, we isolated a new member of the cyclin family. We have characterized the transcript by sequencing, determination of the exon intron boundaries, and Northern blot analysis. Cyclin F is related to A- and B-type cyclins by sequence, but its function is unknown.",

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AU - Snarey, A.

AU - Schneider, M. C.

AU - Reeders, S. T.

AU - Frischauf, A. M.

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A Novel Cyclin Gene (CCNF) in the Region of the Polycystic Kidney Disease Gene (PKD1)

Abstract

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