Abstract
A new Zn2+ fluorescent sensor NIDPA (1) which takes 1,8-naphthalimide as a reporting group and di-2-picolylamine (DPA) as a recognizing group has been synthesized via simple steps. Based on photo-induced electron transfer (PET) mechanism, NIDPA has a nearly 5-fold fluorescent enhancement under simulated physiological conditions corresponding to the binding of Zn2+. Apparent dissociation constant for Zn2+ (Kd) is in the sub-nM range, and Ca2+, Mg2+, Fe3+, Ni2+, and Cr3+ have little influence on fluorescence enhancement.
Original language | English (US) |
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Article number | CL-040809 |
Pages (from-to) | 1392-1393 |
Number of pages | 2 |
Journal | Chemistry Letters |
Volume | 33 |
Issue number | 10 |
DOIs | |
State | Published - Oct 5 2004 |
Externally published | Yes |
ASJC Scopus subject areas
- Chemistry(all)