Abstract
DNA has two critical functions: to provide the cell with the information necessary for macromolecular synthesis and to transmit that information to progeny cells. Genome sequence stability is important for both these functions. Indeed, cells devote significant resources to various DNA repair processes that maintain genome structure and repair alterations that can arise from DNA synthesis errors and assaults from both endogenous and exogenous sources. DNA sequence variation, however, provides the substrate for adaptation, selection, and evolution.
Original language | English (US) |
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Title of host publication | Mobile DNA III |
Publisher | wiley |
Pages | 3-39 |
Number of pages | 37 |
ISBN (Electronic) | 9781683670964 |
ISBN (Print) | 9781555819200 |
DOIs | |
State | Published - May 26 2015 |
Keywords
- Active gene assembly
- Changing cell surface proteins
- Homing endonucleases
- Host immune defense
- Mobile DNA
- Moveable feast
- Saccharomyces cerevisiae
- Switching mating type
- Targeted dna breaks lead
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology