A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones under mild conditions

Kalyan Kumar Pasunooti; Hua Chai; Chantel Nixon Jensen; Bala Kishan Gorityala; Siming Wang; Xue Wei Liu

doi:10.1016/j.tetlet.2010.10.150

A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones under mild conditions

Kalyan Kumar Pasunooti
, Hua Chai
, Chantel Nixon Jensen
, Bala Kishan Gorityala
, Siming Wang
, Xue Wei Liu

Research output: Contribution to journal › Article › peer-review

Abstract

The synthesis of dihydropyrimidinones via a clean multi-component Biginelli reaction under microwave irradiation is reported. The copper-catalyzed process proved to be simple, efficient, economical, and environmentally friendly.

Original language	English (US)
Pages (from-to)	80-84
Number of pages	5
Journal	Tetrahedron Letters
Volume	52
Issue number	1
DOIs	https://doi.org/10.1016/j.tetlet.2010.10.150
State	Published - Jan 5 2011
Externally published	Yes

Keywords

Biginelli reaction
Dihydropyrimidinone
Green chemistry
Microwave reaction
Multi-component reaction

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2010.10.150

Cite this

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title = "A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones under mild conditions",

abstract = "The synthesis of dihydropyrimidinones via a clean multi-component Biginelli reaction under microwave irradiation is reported. The copper-catalyzed process proved to be simple, efficient, economical, and environmentally friendly.",

keywords = "Biginelli reaction, Dihydropyrimidinone, Green chemistry, Microwave reaction, Multi-component reaction",

author = "Pasunooti, \{Kalyan Kumar\} and Hua Chai and Jensen, \{Chantel Nixon\} and Gorityala, \{Bala Kishan\} and Siming Wang and Liu, \{Xue Wei\}",

year = "2011",

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doi = "10.1016/j.tetlet.2010.10.150",

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AU - Pasunooti, Kalyan Kumar

AU - Chai, Hua

AU - Jensen, Chantel Nixon

AU - Gorityala, Bala Kishan

AU - Wang, Siming

AU - Liu, Xue Wei

PY - 2011/1/5

Y1 - 2011/1/5

N2 - The synthesis of dihydropyrimidinones via a clean multi-component Biginelli reaction under microwave irradiation is reported. The copper-catalyzed process proved to be simple, efficient, economical, and environmentally friendly.

AB - The synthesis of dihydropyrimidinones via a clean multi-component Biginelli reaction under microwave irradiation is reported. The copper-catalyzed process proved to be simple, efficient, economical, and environmentally friendly.

KW - Biginelli reaction

KW - Dihydropyrimidinone

KW - Green chemistry

KW - Microwave reaction

KW - Multi-component reaction

UR - https://www.scopus.com/pages/publications/78649857134

UR - https://www.scopus.com/pages/publications/78649857134#tab=citedBy

U2 - 10.1016/j.tetlet.2010.10.150

DO - 10.1016/j.tetlet.2010.10.150

M3 - Article

AN - SCOPUS:78649857134

SN - 0040-4039

VL - 52

SP - 80

EP - 84

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 1

ER -

A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones under mild conditions

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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