TY - GEN
T1 - A machine learning based approach for identifying traumatic brain injury patients for whom a head CT scan can be avoided
AU - Molaei, Somayeh
AU - Korley, Frederick K.
AU - Soroushmehr, S. M.Reza
AU - Falk, Hayley
AU - Sair, Haris
AU - Ward, Kevin
AU - Najarian, Kayvan
PY - 2016/10/13
Y1 - 2016/10/13
N2 - Head CT scan is more often used to evaluate patients with suspected traumatic brain injury (TBI). However, the use of head CT scans in evaluating TBI is costly with low value endeavor. In this paper, we propose a new algorithm and a set of features to help clinicians determine which patients evaluated for TBI need a head CT scan using cost sensitive random forest (CSRF) classifier. We show that random forest (RF) and CSRF are useful methods for identifying patients likely to have a positive head CT scan. The proposed algorithm has superior diagnostic accuracy in comparison to the Canadian head CT algorithm, which is currently the most accurate and widely used algorithm for determining which TBI patients need a head CT scan. In the highest sensitivity (i.e. 100%), our method outperforms the Canadian rule in terms of specificity, accuracy and area under ROC curve using cost sensitive classifier. Clinical implementation of this algorithm can help decrease financial costs associated with Emergency Department evaluations for traumatic brain injury, while decreasing patient exposure to avoidable ionizing radiation.
AB - Head CT scan is more often used to evaluate patients with suspected traumatic brain injury (TBI). However, the use of head CT scans in evaluating TBI is costly with low value endeavor. In this paper, we propose a new algorithm and a set of features to help clinicians determine which patients evaluated for TBI need a head CT scan using cost sensitive random forest (CSRF) classifier. We show that random forest (RF) and CSRF are useful methods for identifying patients likely to have a positive head CT scan. The proposed algorithm has superior diagnostic accuracy in comparison to the Canadian head CT algorithm, which is currently the most accurate and widely used algorithm for determining which TBI patients need a head CT scan. In the highest sensitivity (i.e. 100%), our method outperforms the Canadian rule in terms of specificity, accuracy and area under ROC curve using cost sensitive classifier. Clinical implementation of this algorithm can help decrease financial costs associated with Emergency Department evaluations for traumatic brain injury, while decreasing patient exposure to avoidable ionizing radiation.
KW - Canadian head CT rule
KW - Classification
KW - Head CT scan
KW - Random forest
KW - Traumatic brain injury
UR - http://www.scopus.com/inward/record.url?scp=85009084329&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85009084329&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2016.7591179
DO - 10.1109/EMBC.2016.7591179
M3 - Conference contribution
C2 - 28268778
AN - SCOPUS:85009084329
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 2258
EP - 2261
BT - 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
Y2 - 16 August 2016 through 20 August 2016
ER -