A long-term cohort study of outcome after cholecystectomy for chronic acalculous cholecystitis

Sanjay B. Jagannath, Vikesh K. Singh, Marcia Cruz-Correa, Marcia Irene F. Canto, Anthony N. Kalloo

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Background: Cholecystectomy is effective therapy for chronic calculous cholecystitis (CCC). The long-term outcome of patients treated with cholecystectomy for chronic acalculous cholecystitis (CAC) is unknown. Methods: A controlled, retrospective cohort study assessing biliary pain (preoperative and at follow-up) in postcholecystectomy patients with CAC or CCC was performed. Results: In 19 CAC and with matched CCC control patients, the mean duration of symptoms before surgery was 38.3 months (95% CI, 16.4 to 60.2) and 8.1 months (95% CI, 5.4 to 10.8), respectively. The mean follow-up for both groups was 8.37 ± 1.13 years. Both groups benefited from cholecystectomy (P <0.001), and both were equally likely to be pain-free upon long-term follow-up (95% CAC versus 84% CCC, P >0.05). Conclusions: There was no difference in outcome between the groups after an average follow-up of 8.37 years. Postcholecystectomy patients with chronic cholecystitis and no gallstones have long-term, complete pain resolution, similar to patients with gallstones.

Original languageEnglish (US)
Pages (from-to)91-95
Number of pages5
JournalAmerican journal of surgery
Issue number2
StatePublished - Feb 1 2003


  • Acalculous
  • Cholecystectomy
  • Cholecystitis
  • Chronic
  • Outcome

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'A long-term cohort study of outcome after cholecystectomy for chronic acalculous cholecystitis'. Together they form a unique fingerprint.

Cite this