A holistic approach to promoting early child development: A cluster randomised trial of a group-based, multicomponent intervention in rural Bangladesh

Helen O. Pitchik, Fahmida Tofail, Mahbubur Rahman, Fahmida Akter, Jesmin Sultana, Abul Kasham Shoab, Tarique Md Nurul Huda, Tania Jahir, Md Ruhul Amin, Md Khobair Hossain, Jyoti Bhushan Das, Esther O. Chung, Kendra A. Byrd, Farzana Yeasmin, Laura H. Kwong, Jenna E. Forsyth, Malay K. Mridha, Peter J. Winch, Stephen P. Luby, Lia C.H. Fernald

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Introduction In low-and middle-income countries, children experience multiple risks for delayed development. We evaluated a multicomponent, group-based early child development intervention including behavioural recommendations on responsive stimulation, nutrition, water, sanitation, hygiene, mental health and lead exposure prevention. Methods We conducted a 9-month, parallel, multiarm, cluster-randomised controlled trial in 31 rural villages in Kishoreganj District, Bangladesh. Villages were randomly allocated to: group sessions (â € group'); alternating groups and home visits (â € combined'); or a passive control arm. Sessions were delivered fortnightly by trained community members. The primary outcome was child stimulation (Family Care Indicators); the secondary outcome was child development (Ages and Stages Questionnaire Inventory, ASQi). Other outcomes included dietary diversity, latrine status, use of a child potty, handwashing infrastructure, caregiver mental health and knowledge of lead. Analyses were intention to treat. Data collectors were independent from implementers. Results In July-August 2017, 621 pregnant women and primary caregivers of children<15 months were enrolled (group n=160, combined n=160, control n=301). At endline, immediately following intervention completion (July-August 2018), 574 participants were assessed (group n=144, combined n=149, control n=281). Primary caregivers in both intervention arms participated in more play activities than control caregivers (age-adjusted means: group 4.22, 95% CI 3.97 to 4.47; combined 4.77, 4.60 to 4.96; control 3.24, 3.05 to 3.39), and provided a larger variety of play materials (age-adjusted means: group 3.63, 3.31 to 3.96; combined 3.81, 3.62 to 3.99; control 2.48, 2.34 to 2.59). Compared with the control arm, children in the group arm had higher total ASQi scores (adjusted mean difference in standardised scores: 0.39, 0.15 to 0.64), while in the combined arm scores were not significantly different from the control (0.25,-0.07 to 0.54). Conclusion Our findings suggest that group-based, multicomponent interventions can be effective at improving child development outcomes in rural Bangladesh, and that they have the potential to be delivered at scale. Trial registration number The trial is registered in ISRCTN (ISRCTN16001234).

Original languageEnglish (US)
Article numbere004307
JournalBMJ Global Health
Volume6
Issue number3
DOIs
StatePublished - Mar 16 2021
Externally publishedYes

Keywords

  • child health
  • cluster randomized trial
  • maternal health
  • prevention strategies

ASJC Scopus subject areas

  • Health Policy
  • Public Health, Environmental and Occupational Health

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