@inbook{3c67ecdd8c534c29baa7b69ee91b06bd,
title = "A guide to the development of human corneaorganoids from induced pluripotent stem cells in culture",
abstract = "The cornea is the outermost transparent and refractive barrier surface of the eye necessary for vision. Development of the cornea involves the coordinated production of extracellular matrix, epithelial differentiation, and endothelial cell expansion to produce a highly transparent tissue. Here we describe the production of multilayered three-dimensional organoids from human-induced pluripotent stem cells. These organoids have the potential for multiple downstream applications which are currently unattainable using traditional in vitro techniques.",
keywords = "Cornea, Corneal epithelium, Corneal stroma, Organoids, iPSC",
author = "Foster, {James W.} and Wahlin, {Karl J.} and Shukti Chakravarti",
note = "Funding Information: This work was supported by the NIH EY026104 (SC) and R00EY024648 (KW). Publisher Copyright: {\textcopyright} Springer Science+Business Media, LLC, part of Springer Nature 2020.",
year = "2020",
doi = "10.1007/978-1-0716-0599-8_5",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "51--58",
booktitle = "Methods in Molecular Biology",
}