A fluoxetine-induced frontal lobe syndrome in an obsessive compulsive patient

R. Hoehn-Saric; G. J. Harris; G. D. Pearlson; C. S. Cox; S. R. Machlin; E. E. Camargo

A fluoxetine-induced frontal lobe syndrome in an obsessive compulsive patient

R. Hoehn-Saric, G. J. Harris, G. D. Pearlson, C. S. Cox, S. R. Machlin, E. E. Camargo

School of Medicine

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

The authors report the occurrence of apathy, indifference, inattention, and perserveration in an obsessive compulsive patient taking high doses of fluoxetine. These changes were associated with a decrease in cerebral blood flow in the frontal lobes and changes in neuropsychological tests generally associated with frontal lobe impairment. These clinical manifestations disappeared 4 weeks after discontinuation of fluoxetine.

Original language	English (US)
Pages (from-to)	131-133
Number of pages	3
Journal	Journal of Clinical Psychiatry
Volume	52
Issue number	3
State	Published - 1991

ASJC Scopus subject areas

Psychiatry and Mental health

Cite this

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title = "A fluoxetine-induced frontal lobe syndrome in an obsessive compulsive patient",

abstract = "The authors report the occurrence of apathy, indifference, inattention, and perserveration in an obsessive compulsive patient taking high doses of fluoxetine. These changes were associated with a decrease in cerebral blood flow in the frontal lobes and changes in neuropsychological tests generally associated with frontal lobe impairment. These clinical manifestations disappeared 4 weeks after discontinuation of fluoxetine.",

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AU - Machlin, S. R.

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A fluoxetine-induced frontal lobe syndrome in an obsessive compulsive patient

Abstract

ASJC Scopus subject areas

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