A facile method for the synthesis of substituted pyrazolo[3,4-c]pyridines

Sharad K. Verma, Louis V. LaFrance

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Methods for a facile high-yielding synthesis of substituted pyrazolo[3,4-c]pyridines from 2-bromo-5-fluoropyridine are described, along with a brief mechanistic discussion for the key cyclization step. The methods utilize inexpensive commercially available starting materials and unlike previous methods, are more suitable for SAR work and scale-up.

Original languageEnglish (US)
Pages (from-to)383-385
Number of pages3
JournalTetrahedron Letters
Issue number4
StatePublished - Jan 28 2009
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


Dive into the research topics of 'A facile method for the synthesis of substituted pyrazolo[3,4-c]pyridines'. Together they form a unique fingerprint.

Cite this