A CRISPR way to engineer the human genome

Sivaprakash Ramalingam, Narayana Annaluru, Srinivasan Chandrasegaran

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an effi cient and versatile method for targeted manipulation of mammalian genomes.

Original languageEnglish (US)
Article number107
JournalGenome biology
Issue number2
StatePublished - Feb 26 2013
Externally publishedYes

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology


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