A compendium of proteins that interact with HIF-1α

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37 Scopus citations


Hypoxia-inducible factor 1 (HIF-1) is the founding member of a family of transcription factors that function as master regulators of oxygen homeostasis. HIF-1 is composed of an O2-regulated HIF-1α subunit and a constitutively expressed HIF-1β subunit. This review provides a compendium of proteins that interact with the HIF-1α subunit, many of which regulate HIF-1 activity in either an O2-dependent or O2-independent manner.

Original languageEnglish (US)
Pages (from-to)128-135
Number of pages8
JournalExperimental cell research
Issue number2
StatePublished - Jul 15 2017


  • Oxygen biology
  • Transcriptional regulation

ASJC Scopus subject areas

  • Cell Biology


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