A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning

W. Thomas Hrinivich; Douglas A. Hoover; Kathleen Surry; Chandima Edirisinghe; Jacques Montreuil; David D'Souza; Aaron Fenster; Eugene Wong

doi:10.1117/12.2216149

A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning

W. Thomas Hrinivich, Douglas A. Hoover, Kathleen Surry, Chandima Edirisinghe, Jacques Montreuil, David D'Souza, Aaron Fenster, Eugene Wong

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Background: High-dose-rate brachytherapy (HDR-BT) is a prostate cancer treatment option involving the insertion of hollow needles into the gland through the perineum to deliver a radioactive source. Conventional needle imaging involves indexing a trans-rectal ultrasound (TRUS) probe in the superior/inferior (S/I) direction, using the axial transducer to produce an image set for organ segmentation. These images have limited resolution in the needle insertion direction (S/I), so the sagittal transducer is used to identify needle tips, requiring a manual registration with the axial view. This registration introduces a source of uncertainty in the final segmentations and subsequent treatment plan. Our lab has developed a device enabling 3D-TRUS guided insertions with high S/I spatial resolution, eliminating the need to align axial and sagittal views. Purpose: To compare HDR-BT needle tip localization accuracy between 2D and 3D-TRUS. Methods: 5 prostate cancer patients underwent conventional 2D TRUS guided HDR-BT, during which 3D images were also acquired for post-operative registration and segmentation. Needle end-length measurements were taken, providing a gold standard for insertion depths. Results: 73 needles were analyzed from all 5 patients. Needle tip position differences between imaging techniques was found to be largest in the S/I direction with mean±SD of-2.5±4.0 mm. End-length measurements indicated that 3D TRUS provided statistically significantly lower mean±SD insertion depth error of-0.2±3.4 mm versus 2.3±3.7 mm with 2D guidance (p <.001). Conclusions: 3D TRUS may provide more accurate HDR-BT needle localization than conventional 2D TRUS guidance for the majority of HDR-BT needles.

Original language	English (US)
Title of host publication	Medical Imaging 2016
Subtitle of host publication	Image-Guided Procedures, Robotic Interventions, and Modeling
Editors	Robert J. Webster, Ziv R. Yaniv
Publisher	SPIE
ISBN (Electronic)	9781510600218
DOIs	https://doi.org/10.1117/12.2216149
State	Published - 2016
Externally published	Yes
Event	Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling - San Diego, United States Duration: Feb 28 2016 → Mar 1 2016

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	9786
ISSN (Print)	1605-7422

Other

Other	Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling
Country/Territory	United States
City	San Diego
Period	2/28/16 → 3/1/16

Keywords

3D ultrasound
brachytherapy
needle segmentation
prostate cancer
radiation therapy

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.2216149

Cite this

Hrinivich, W. T., Hoover, D. A., Surry, K., Edirisinghe, C., Montreuil, J., D'Souza, D., Fenster, A., & Wong, E. (2016). A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning. In R. J. Webster, & Z. R. Yaniv (Eds.), Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling Article 97861H (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9786). SPIE. https://doi.org/10.1117/12.2216149

A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning. / Hrinivich, W. Thomas; Hoover, Douglas A.; Surry, Kathleen et al.
Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling. ed. / Robert J. Webster; Ziv R. Yaniv. SPIE, 2016. 97861H (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9786).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Hrinivich, WT, Hoover, DA, Surry, K, Edirisinghe, C, Montreuil, J, D'Souza, D, Fenster, A & Wong, E 2016, A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning. in RJ Webster & ZR Yaniv (eds), Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling., 97861H, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 9786, SPIE, Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling, San Diego, United States, 2/28/16. https://doi.org/10.1117/12.2216149

Hrinivich WT, Hoover DA, Surry K, Edirisinghe C, Montreuil J, D'Souza D et al. A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning. In Webster RJ, Yaniv ZR, editors, Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling. SPIE. 2016. 97861H. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2216149

Hrinivich, W. Thomas ; Hoover, Douglas A. ; Surry, Kathleen et al. / A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning. Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling. editor / Robert J. Webster ; Ziv R. Yaniv. SPIE, 2016. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

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title = "A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning",

abstract = "Background: High-dose-rate brachytherapy (HDR-BT) is a prostate cancer treatment option involving the insertion of hollow needles into the gland through the perineum to deliver a radioactive source. Conventional needle imaging involves indexing a trans-rectal ultrasound (TRUS) probe in the superior/inferior (S/I) direction, using the axial transducer to produce an image set for organ segmentation. These images have limited resolution in the needle insertion direction (S/I), so the sagittal transducer is used to identify needle tips, requiring a manual registration with the axial view. This registration introduces a source of uncertainty in the final segmentations and subsequent treatment plan. Our lab has developed a device enabling 3D-TRUS guided insertions with high S/I spatial resolution, eliminating the need to align axial and sagittal views. Purpose: To compare HDR-BT needle tip localization accuracy between 2D and 3D-TRUS. Methods: 5 prostate cancer patients underwent conventional 2D TRUS guided HDR-BT, during which 3D images were also acquired for post-operative registration and segmentation. Needle end-length measurements were taken, providing a gold standard for insertion depths. Results: 73 needles were analyzed from all 5 patients. Needle tip position differences between imaging techniques was found to be largest in the S/I direction with mean±SD of-2.5±4.0 mm. End-length measurements indicated that 3D TRUS provided statistically significantly lower mean±SD insertion depth error of-0.2±3.4 mm versus 2.3±3.7 mm with 2D guidance (p <.001). Conclusions: 3D TRUS may provide more accurate HDR-BT needle localization than conventional 2D TRUS guidance for the majority of HDR-BT needles.",

keywords = "3D ultrasound, brachytherapy, needle segmentation, prostate cancer, radiation therapy",

author = "Hrinivich, {W. Thomas} and Hoover, {Douglas A.} and Kathleen Surry and Chandima Edirisinghe and Jacques Montreuil and David D'Souza and Aaron Fenster and Eugene Wong",

note = "Funding Information: This study was supported by the Canadian Institutes of Health Research (CIHR, funding reference number 140352), the Cancer Research and Technology Transfer (CaRTT) Strategic Training Program, and the Ontario Institute for Cancer Research (OICR) Imaging Translation Program. Publisher Copyright: {\textcopyright} 2016 SPIE.; Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling ; Conference date: 28-02-2016 Through 01-03-2016",

year = "2016",

doi = "10.1117/12.2216149",

language = "English (US)",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Webster, {Robert J.} and Yaniv, {Ziv R.}",

booktitle = "Medical Imaging 2016",

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T1 - A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning

AU - Hrinivich, W. Thomas

AU - Hoover, Douglas A.

AU - Surry, Kathleen

AU - Edirisinghe, Chandima

AU - Montreuil, Jacques

AU - D'Souza, David

AU - Fenster, Aaron

AU - Wong, Eugene

N1 - Funding Information: This study was supported by the Canadian Institutes of Health Research (CIHR, funding reference number 140352), the Cancer Research and Technology Transfer (CaRTT) Strategic Training Program, and the Ontario Institute for Cancer Research (OICR) Imaging Translation Program. Publisher Copyright: © 2016 SPIE.

PY - 2016

Y1 - 2016

N2 - Background: High-dose-rate brachytherapy (HDR-BT) is a prostate cancer treatment option involving the insertion of hollow needles into the gland through the perineum to deliver a radioactive source. Conventional needle imaging involves indexing a trans-rectal ultrasound (TRUS) probe in the superior/inferior (S/I) direction, using the axial transducer to produce an image set for organ segmentation. These images have limited resolution in the needle insertion direction (S/I), so the sagittal transducer is used to identify needle tips, requiring a manual registration with the axial view. This registration introduces a source of uncertainty in the final segmentations and subsequent treatment plan. Our lab has developed a device enabling 3D-TRUS guided insertions with high S/I spatial resolution, eliminating the need to align axial and sagittal views. Purpose: To compare HDR-BT needle tip localization accuracy between 2D and 3D-TRUS. Methods: 5 prostate cancer patients underwent conventional 2D TRUS guided HDR-BT, during which 3D images were also acquired for post-operative registration and segmentation. Needle end-length measurements were taken, providing a gold standard for insertion depths. Results: 73 needles were analyzed from all 5 patients. Needle tip position differences between imaging techniques was found to be largest in the S/I direction with mean±SD of-2.5±4.0 mm. End-length measurements indicated that 3D TRUS provided statistically significantly lower mean±SD insertion depth error of-0.2±3.4 mm versus 2.3±3.7 mm with 2D guidance (p <.001). Conclusions: 3D TRUS may provide more accurate HDR-BT needle localization than conventional 2D TRUS guidance for the majority of HDR-BT needles.

AB - Background: High-dose-rate brachytherapy (HDR-BT) is a prostate cancer treatment option involving the insertion of hollow needles into the gland through the perineum to deliver a radioactive source. Conventional needle imaging involves indexing a trans-rectal ultrasound (TRUS) probe in the superior/inferior (S/I) direction, using the axial transducer to produce an image set for organ segmentation. These images have limited resolution in the needle insertion direction (S/I), so the sagittal transducer is used to identify needle tips, requiring a manual registration with the axial view. This registration introduces a source of uncertainty in the final segmentations and subsequent treatment plan. Our lab has developed a device enabling 3D-TRUS guided insertions with high S/I spatial resolution, eliminating the need to align axial and sagittal views. Purpose: To compare HDR-BT needle tip localization accuracy between 2D and 3D-TRUS. Methods: 5 prostate cancer patients underwent conventional 2D TRUS guided HDR-BT, during which 3D images were also acquired for post-operative registration and segmentation. Needle end-length measurements were taken, providing a gold standard for insertion depths. Results: 73 needles were analyzed from all 5 patients. Needle tip position differences between imaging techniques was found to be largest in the S/I direction with mean±SD of-2.5±4.0 mm. End-length measurements indicated that 3D TRUS provided statistically significantly lower mean±SD insertion depth error of-0.2±3.4 mm versus 2.3±3.7 mm with 2D guidance (p <.001). Conclusions: 3D TRUS may provide more accurate HDR-BT needle localization than conventional 2D TRUS guidance for the majority of HDR-BT needles.

KW - 3D ultrasound

KW - brachytherapy

KW - needle segmentation

KW - prostate cancer

KW - radiation therapy

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ER -

A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning

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