A Case of Scedosporium aurantiacum Infection in the United States

Masako Mizusawa, Marissa Totten, Sean X. Zhang

Research output: Contribution to journalArticlepeer-review


Scedosporium aurantiacum is one of the emergent opportunistic fungal pathogens among immunocompromised hosts. Colonization of S. aurantiacum can also occur in patients with underlying lung diseases such as cystic fibrosis. S. aurantiacum is highly resistant to multiple antifungal agents, and management of the infected patients can be very challenging compared to those infected with other species of Scedosporium. Clinical cases have been geographically restricted mostly in Australia with a small number of cases identified in Europe and Japan. Although clinical isolates of S. aurantiacum from the USA have been included in several research studies, no clinical case of S. aurantiacum infection from the USA has been described. We report a case of S. aurantiacum infection acquired in the SA. Awareness of S. aurantiacum among healthcare providers and the species-level identification for Scedosporium are critically important for appropriate selection of antifungal agents and improvement of treatment outcomes.

Original languageEnglish (US)
Pages (from-to)127-130
Number of pages4
Issue number1
StatePublished - Mar 2021


  • Invasive fungal infection
  • Multi-drug resistance
  • Scedosporium aurantiacum
  • The USA

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Agronomy and Crop Science
  • veterinary (miscalleneous)
  • Microbiology


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