A case of male pseudohermaphroditism associated with elevated LH, normal FSH and low testosterone possibly due to the secretion of an abnormal LH molecule

I. J. Park; L. S. Burnett; H. W. Jones; C. J. Migeon; R. M. Blizzard

doi:10.1530/acta.0.0830173

A case of male pseudohermaphroditism associated with elevated LH, normal FSH and low testosterone possibly due to the secretion of an abnormal LH molecule

I. J. Park, L. S. Burnett, H. W. Jones, C. J. Migeon, R. M. Blizzard

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

A 27 yr old female is described who had 46,XY chromosome complement, ambiguous external genitalia with elevated LH, slightly above normal FSH and low testosterone. Her plasma testosterone level increased 15 to 20 fold after HCG stimulation (5000 IU x 3), then returned to prestimulation level 3 mth later. This was possibly due to the secretion of an abnormal LH molecule which is immunoreactive but biologically inactive in the human.

Original language	English (US)
Pages (from-to)	173-181
Number of pages	9
Journal	Unknown Journal
Volume	83
Issue number	1
DOIs	https://doi.org/10.1530/acta.0.0830173
State	Published - 1976
Externally published	Yes

ASJC Scopus subject areas

Endocrinology

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title = "A case of male pseudohermaphroditism associated with elevated LH, normal FSH and low testosterone possibly due to the secretion of an abnormal LH molecule",

abstract = "A 27 yr old female is described who had 46,XY chromosome complement, ambiguous external genitalia with elevated LH, slightly above normal FSH and low testosterone. Her plasma testosterone level increased 15 to 20 fold after HCG stimulation (5000 IU x 3), then returned to prestimulation level 3 mth later. This was possibly due to the secretion of an abnormal LH molecule which is immunoreactive but biologically inactive in the human.",

author = "Park, {I. J.} and Burnett, {L. S.} and Jones, {H. W.} and Migeon, {C. J.} and Blizzard, {R. M.}",

year = "1976",

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AU - Jones, H. W.

AU - Migeon, C. J.

AU - Blizzard, R. M.

PY - 1976

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A case of male pseudohermaphroditism associated with elevated LH, normal FSH and low testosterone possibly due to the secretion of an abnormal LH molecule

Abstract

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