A case of combined central and peripheral demyelination in Zambia

Ilena C. George, Michelle Kvalsund, Deanna Saylor

Research output: Contribution to journalArticlepeer-review


Overlap syndromes, where otherwise distinct autoimmune processes of the central and peripheral nervous systems are present in the same patient, are uncommon and have not been previously reported in sub-Saharan Africa. We present a case of a 32-year-old man who was found to have both clinically isolated syndrome and chronic inflammatory demyelinating polyneuropathy, highlighting the importance of continued efforts to establish the prevalence of demyelinating disease in the region given the limited treatment options currently available for autoimmune disease.

Original languageEnglish (US)
Article number101943
JournalMultiple Sclerosis and Related Disorders
StatePublished - May 2020


  • Autoimmune diseases
  • Chronic inflammatory demyelinating
  • Developing countries
  • Multiple sclerosis
  • Polyradiculoneuropathy
  • Undifferentiated connective tissue diseases

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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