TY - JOUR
T1 - A 4-year old presenting with fever and achiness
AU - Plott, Caroline
AU - Gracie, Thomas
AU - Alvis, Courtney
AU - Schlefman, Amanda
AU - Dudas, Robert
N1 - Publisher Copyright:
© The Author(s) 2021.
PY - 2021
Y1 - 2021
N2 - In children under the age of 5 who have abnormalities in history, physical examination, and laboratory studies indicating multi-system disease, uncovering the correct diagnosis is challenging. Here, we report the course of a 4-year-old girl who presented with a change in behavior, fever, arthralgia, arthritis, and hematuria following three recent hospitalizations for pneumonia and impetigo. Serologic findings were suggestive of a rheumatologic etiology and a renal biopsy was consistent with Membranous Lupus Nephritis Class V which helped secure the diagnosis of pediatric systemic lupus erythematosus. We review the clinical features and diagnostic criteria of early-onset systemic lupus erythematosus and discuss diagnostic considerations and prognosis.
AB - In children under the age of 5 who have abnormalities in history, physical examination, and laboratory studies indicating multi-system disease, uncovering the correct diagnosis is challenging. Here, we report the course of a 4-year-old girl who presented with a change in behavior, fever, arthralgia, arthritis, and hematuria following three recent hospitalizations for pneumonia and impetigo. Serologic findings were suggestive of a rheumatologic etiology and a renal biopsy was consistent with Membranous Lupus Nephritis Class V which helped secure the diagnosis of pediatric systemic lupus erythematosus. We review the clinical features and diagnostic criteria of early-onset systemic lupus erythematosus and discuss diagnostic considerations and prognosis.
KW - Rheumatology/clinical immunology
KW - nephrology
KW - pathology
UR - http://www.scopus.com/inward/record.url?scp=85118305406&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85118305406&partnerID=8YFLogxK
U2 - 10.1177/2050313X211056416
DO - 10.1177/2050313X211056416
M3 - Article
C2 - 34733521
AN - SCOPUS:85118305406
SN - 2050-313X
VL - 9
JO - SAGE Open Medical Case Reports
JF - SAGE Open Medical Case Reports
ER -