A 36-year-old patient with a multinodular lesion in the left temporal lobe

Simona Gaudino, Carmelo Lucio Sturiale, Emanuela Ruberto, Cesare Colosimo, Alessandro Olivi, Marco Gessi

Research output: Contribution to journalComment/debatepeer-review

1 Scopus citations


A 36-year-old female patient was referred to our hospital for a six-months clinical history of episodes of right-sided focal motor seizures and absence. MRI scan showed a multi-nodular lesion in the subcortical white matter of left superior temporal gyrus. After a complete resection, the neuropathological examination revealed a lesion with marked cell vacuolation which was composed of neuroepithelial cells ranging from small to medium sized elements to larger, neuron-like cells, occasionally bi-nucleated. The neuropathological features of the lesion were compatible with the diagnosis of multinodular and vacuolating neuronal tumor (MVNT) of the CNS. MVNT is very rare, recently described entity among the large spectrum of glioneuronal tumors. It is characterized by benign clinical behavior and neurosurgical resection usually provide control of disease.

Original languageEnglish (US)
Pages (from-to)100-101
Number of pages2
JournalJournal of Clinical Neuroscience
StatePublished - Apr 2018
Externally publishedYes


  • Central nervous system
  • Epilepsy
  • Glioneuronal tumor
  • MVNT
  • Multinodular and vacuolating neuronal tumor

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)


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