6-Mercaptopurine metabolism in Crohn's disease: Correlation with efficacy and toxicity

Keyphrases

• Crohn's Disease 100%
• Metabolism 100%
• 6-mercaptopurine (6-MP) 100%
• Disease Correlation 100%
• Methyl 50%
• Mercaptopurine 50%
• Erythrocytes 40%
• 6-Thioguanine (6-TG) 40%
• Disease Activity 20%
• Treatment Effect 10%
• Neutropenia 10%
• Pancreatitis 10%
• Clinical Remission 10%
• Base-free 10%
• Cytotoxicity 10%
• Remission 10%
• Patient Assessment 10%
• Adverse Effects 10%
• Poor Compliance 10%
• High-performance Liquid Chromatography 10%
• Red Blood Cells 10%
• Prednisone 10%
• Reversed-phase HPLC 10%
• Patient Compliance 10%
• Hepatitis 10%
• Heparinized Blood 10%
• Colitis 10%
• Ileocolitis 10%
• Metabolite Concentrations 10%
• Thiopurine Methyltransferase 10%
• Activity Effect 10%
• Drug Adherence 10%
• Patient Responsiveness 10%
• Marrow Suppression 10%
• Compliance to Treatment 10%
• Harvey-Bradshaw Index 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Crohn's Disease 100%
• Mercaptopurine 100%
• Tioguanine 26%
• Remission 13%
• Disease Activity 13%
• Adverse Event 6%
• Side Effect 6%
• Cytotoxicity 6%
• Neutropenia 6%
• Pancreatitis 6%
• High Performance Liquid Chromatography 6%
• Prednisone 6%
• Immunosuppressive Agent 6%
• Reverse Phase High Performance Liquid Chromatography 6%
• Colitis 6%
• Inflammatory Bowel Disease 6%
• Thiopurine Methyltransferase 6%