2,6-dansyl azide as a fluorescent probe for hydrogen sulfide

Ke Wang; Hanjing Peng; Nanting Ni; Chaofeng Dai; Binghe Wang

doi:10.1007/s10895-013-1296-5

2,6-dansyl azide as a fluorescent probe for hydrogen sulfide

Ke Wang, Hanjing Peng, Nanting Ni, Chaofeng Dai, Binghe Wang

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

A second-generation sulfonyl azide-based fluorescent probe, 2,6-DNS-Az, has been developed for the quantitative detection of H₂S in aqueous media such as phosphate buffer and bovine serum. Compare to the first-generation 1,5-DNS-Az probe, this probe shows both high sensitivity in phosphate buffer without the need for addition of surfactant and selectivity for sulfide over other anions and biomolecules, and thus can be used as a useful tool for detection of H₂S in the biological system.

Original language	English (US)
Pages (from-to)	1-5
Number of pages	5
Journal	Journal of Fluorescence
Volume	24
Issue number	1
DOIs	https://doi.org/10.1007/s10895-013-1296-5
State	Published - Jan 2014
Externally published	Yes

Keywords

Azide
Fluorescent probe
Gasotransmitter
Hydrogen sulfide
Redox sensing

ASJC Scopus subject areas

Biochemistry
Clinical Psychology
Social Sciences (miscellaneous)
Sociology and Political Science
Spectroscopy
Clinical Biochemistry
Law

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10.1007/s10895-013-1296-5

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title = "2,6-dansyl azide as a fluorescent probe for hydrogen sulfide",

abstract = "A second-generation sulfonyl azide-based fluorescent probe, 2,6-DNS-Az, has been developed for the quantitative detection of H2S in aqueous media such as phosphate buffer and bovine serum. Compare to the first-generation 1,5-DNS-Az probe, this probe shows both high sensitivity in phosphate buffer without the need for addition of surfactant and selectivity for sulfide over other anions and biomolecules, and thus can be used as a useful tool for detection of H2S in the biological system.",

keywords = "Azide, Fluorescent probe, Gasotransmitter, Hydrogen sulfide, Redox sensing",

author = "Ke Wang and Hanjing Peng and Nanting Ni and Chaofeng Dai and Binghe Wang",

note = "Funding Information: Acknowledgment We are grateful for the financial support from Chinese Scholarship Council (KW), Molecular Basis of Disease for a fellowship (HP), and Center for Diagnostics and Therapeutics for a CDT/University fellowship (HP).",

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T1 - 2,6-dansyl azide as a fluorescent probe for hydrogen sulfide

AU - Wang, Ke

AU - Peng, Hanjing

AU - Ni, Nanting

AU - Dai, Chaofeng

AU - Wang, Binghe

N1 - Funding Information: Acknowledgment We are grateful for the financial support from Chinese Scholarship Council (KW), Molecular Basis of Disease for a fellowship (HP), and Center for Diagnostics and Therapeutics for a CDT/University fellowship (HP).

PY - 2014/1

Y1 - 2014/1

N2 - A second-generation sulfonyl azide-based fluorescent probe, 2,6-DNS-Az, has been developed for the quantitative detection of H2S in aqueous media such as phosphate buffer and bovine serum. Compare to the first-generation 1,5-DNS-Az probe, this probe shows both high sensitivity in phosphate buffer without the need for addition of surfactant and selectivity for sulfide over other anions and biomolecules, and thus can be used as a useful tool for detection of H2S in the biological system.

AB - A second-generation sulfonyl azide-based fluorescent probe, 2,6-DNS-Az, has been developed for the quantitative detection of H2S in aqueous media such as phosphate buffer and bovine serum. Compare to the first-generation 1,5-DNS-Az probe, this probe shows both high sensitivity in phosphate buffer without the need for addition of surfactant and selectivity for sulfide over other anions and biomolecules, and thus can be used as a useful tool for detection of H2S in the biological system.

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KW - Fluorescent probe

KW - Gasotransmitter

KW - Hydrogen sulfide

KW - Redox sensing

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2,6-dansyl azide as a fluorescent probe for hydrogen sulfide

Abstract

Keywords

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