2,5-dimethoxy-4-methyl-amphetamine (STP): A new hallucinogenic drug

Solomon H. Snyder, Louis Faillace, Leo Hollister

Research output: Contribution to journalArticlepeer-review

86 Scopus citations


We have assessed the effects in normal control volunteers of 2,5dimethoxy-4-methyl-amphetamine, the chemical present in the hallucinogenic drug STP, in two independent trials. In low doses, this compound produces a mild euphoria. Doses greater than 3 milligrams may cause pronounced hallucinogenic effects lasting about 8 hours and similar to those produced by hallucinogenic doses of lysergic acid diethylamide, mescaline, and psilocybin. 2,5-Dimethoxy4-methyl-amphetamine, which is chemically related to mescaline and amphetamine, is about 100 times more potent as a hallucinogen than mescaline and only one-thirtieth as potent as lysergic acid diethylamide. Its psychological effects are not accentuated by chlorpromazine.

Original languageEnglish (US)
Pages (from-to)669-670
Number of pages2
StatePublished - 1967

ASJC Scopus subject areas

  • General


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