Research output per year
Research output per year
- 1 - 50 out of 80 results
Search results
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2024
Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis activation
Song, Q., Hwang, C. L., Li, Y., Wang, J., Park, J., Lee, S. M., Sun, Z., Sun, J., Xia, Y., Nieto, N., Cordoba-Chacon, J., Jiang, Y., Dou, X. & Song, Z., Feb 2024, In: Metabolism: clinical and experimental. 151, 155740.Research output: Contribution to journal › Article › peer-review
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Induction of Skin Allograft Chimerism by Pharmacological Mobilization of Endogenous Bone Marrow-Derived Stem Cells
Ahmadi, A. R., Wesson, R. N., Huang, J., Harmon, J., Burdick, J. F., Cameron, A. & Sun, Z., Jan 5 2024, In: Journal of burn care & research : official publication of the American Burn Association. 45, 1, p. 234-241 8 p.Research output: Contribution to journal › Article › peer-review
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2023
A phase I, first-in-human study to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of MRG-001 in healthy subjects
Ahmadi, A. R., Atiee, G., Chapman, B., Reynolds, L., Sun, J., Cameron, A. M., Wesson, R. N., Burdick, J. F. & Sun, Z., Sep 19 2023, In: Cell Reports Medicine. 4, 9, 101169.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery and characterization of cross-reactive intrahepatic antibodies in severe alcoholic hepatitis
Ahmadi, A. R., Song, G., Gao, T., Ma, J., Han, X., Hu, M. W., Cameron, A. M., Wesson, R. N., Philosophe, B., Ottmann, S., King, E., Gurakar, A., Qi, L., Peiffer, B., Burdick, J., Anders, R., Zhou, Z., Lu, H., Feng, D., Chen, C. S., & 4 others, 2023, In: eLife. 12, RP86678.Research output: Contribution to journal › Article › peer-review
Open Access -
Inhibition of Abelson Tyrosine-Protein Kinase 2 Suppresses the Development of Alcohol-Associated Liver Disease by Decreasing PPARgamma Expression
Malnassy, G., Keating, C. R., Gad, S., Bridgeman, B., Perera, A., Hou, W., Cotler, S. J., Ding, X., Choudhry, M., Sun, Z., Koleske, A. J. & Qiu, W., Jan 2023, In: CMGH. 16, 5, p. 685-709 25 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Loss of long-chain acyl-CoA synthetase 1 promotes hepatocyte death in alcohol-induced steatohepatitis
Dong, H., Zhong, W., Zhang, W., Hao, L., Guo, W., Yue, R., Sun, X., Sun, Z., Bataller, R. & Zhou, Z., Jan 2023, In: Metabolism: clinical and experimental. 138, 155334.Research output: Contribution to journal › Article › peer-review
Open Access -
Loss of SQSTM1/p62 Induces Obesity and Exacerbates Alcohol-Induced Liver Injury in Aged Mice
Qian, H., Chao, X., Wang, S., Li, Y., Jiang, X., Sun, Z., Rülicke, T., Zatloukal, K., Ni, H. M. & Ding, W. X., Jan 2023, In: CMGH. 15, 5, p. 1027-1049 23 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Persistent mTORC1 activation due to loss of liver tuberous sclerosis complex 1 promotes liver injury in alcoholic hepatitis
Chao, X., Wang, S., Ma, X., Zhang, C., Qian, H., Williams, S. N., Sun, Z., Peng, Z., Liu, W., Li, F., Sheshadri, N., Zong, W. X., Ni, H. M. & Ding, W. X., Aug 2023, In: Hepatology. 78, 2, p. 503-517 15 p.Research output: Contribution to journal › Article › peer-review
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全胰腺切除胰岛自体移植治疗慢性或复发性急性胰腺炎的研究进展
Translated title of the contribution :Research progress of total pancreatectomy with islet autotransplantation for chronic pancreatitis or recurrent acute pancreatitis Research output: Contribution to journal › Article › peer-review
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2022
Bile Acid–Mediated Activation of Brown Fat Protects From Alcohol-Induced Steatosis and Liver Injury in Mice
Fan, M., Wang, Y., Jin, L., Fang, Z., Peng, J., Tu, J., Liu, Y., Zhang, E., Xu, S., Liu, X., Huo, Y., Sun, Z., Chao, X., Ding, W. X., Yan, Q. & Huang, W., Jan 2022, In: CMGH. 13, 3, p. 809-826 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease
Barbier-Torres, L., Murray, B., Yang, J. W., Wang, J., Matsuda, M., Robinson, A., Binek, A., Fan, W., Fernández-Ramos, D., Lopitz-Otsoa, F., Luque-Urbano, M., Millet, O., Mavila, N., Peng, H., Ramani, K., Gottlieb, R., Sun, Z., Liangpunsakul, S., Seki, E., Van Eyk, J. E., & 2 others, Dec 2022, In: Nature communications. 13, 1, 557.Research output: Contribution to journal › Article › peer-review
Open Access -
Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure
Ma, J., Guillot, A., Yang, Z., Mackowiak, B., Hwang, S., Park, O., Peiffer, B. J., Ahmadi, A. R., Melo, L., Kusumanchi, P., Huda, N., Saxena, R., He, Y., Guan, Y., Feng, D., Sancho-Bru, P., Zang, M., Cameron, A. M. G., Bataller, R., Tacke, F., & 3 others, Jul 15 2022, In: Journal of Clinical Investigation. 132, 14, e157780.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluating the Immunopathogenesis of Diabetes after Acute Pancreatitis in the D iabetes RE lated to A cute Pancreatitis and Its M echanisms Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium
Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC), Jul 1 2022, In: Pancreas. 51, 6, p. 580-585 6 p.Research output: Contribution to journal › Article › peer-review
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Hepatic recruitment of eosinophils and their protective function during acute liver injury
Xu, L., Yang, Y., Wen, Y., Jeong, J. M., Emontzpohl, C., Atkins, C. L., Sun, Z., Poulsen, K. L., Hall, D. R., Steve Bynon, J., Gao, B., Lee, W. M., Rule, J., Jacobsen, E. A., Wang, H. & Ju, C., Aug 2022, In: Journal of Hepatology. 77, 2, p. 344-352 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteomic analysis of alcohol-associated hepatitis reveals glycoprotein NMB (GPNMB) as a novel hepatic and serum biomarker
Harris, P. S., Michel, C. R., Yun, Y., McGinnis, C. D., Assiri, M. A., Ahmadi, A. R., Sun, Z., Roede, J. R., Burchill, M. A., Orlicky, D. J., McCullough, R. L. & Fritz, K. S., Mar 2022, In: Alcohol. 99, p. 35-48 14 p.Research output: Contribution to journal › Article › peer-review
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Telomere length in patients with alcohol-associated liver disease: A brief report
Huda, N., Kusumanchi, P., Perez, K., Jiang, Y., Skill, N. J., Sun, Z., Ma, J., Yang, Z. & Liangpunsakul, S., Aug 1 2022, In: Journal of Investigative Medicine. 70, 6, p. 1438-1441 4 p.Research output: Contribution to journal › Article › peer-review
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Type 1 Diabetes in Acute Pancreatitis Consortium: From Concept to Reality
Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC), Jul 1 2022, In: Pancreas. 51, 6, p. 563-567 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
ATF4 activation promotes hepatic mitochondrial dysfunction by repressing NRF1-TFAM signalling in alcoholic steatohepatitis
Hao, L., Zhong, W., Dong, H., Guo, W., Sun, X., Zhang, W., Yue, R., Li, T., Griffiths, A., Ahmadi, A. R., Sun, Z., Song, Z. & Zhou, Z., Oct 1 2021, In: Gut. 70, 10, p. 1933-1945 13 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway
Xu, L., Zhang, X., Xin, Y., Ma, J., Yang, C., Zhang, X., Hou, G., Dong, X. C., Sun, Z., Xiong, X. & Cao, X., Jul 2021, In: Cell Death and Disease. 12, 7, 710.Research output: Contribution to journal › Article › peer-review
Open Access -
Integrated Multiomics Reveals Glucose Use Reprogramming and Identifies a Novel Hexokinase in Alcoholic Hepatitis
Massey, V., Parrish, A., Argemi, J., Moreno, M., Mello, A., García-Rocha, M., Altamirano, J., Odena, G., Dubuquoy, L., Louvet, A., Martinez, C., Adrover, A., Affò, S., Morales-Ibanez, O., Sancho-Bru, P., Millán, C., Alvarado-Tapias, E., Morales-Arraez, D., Caballería, J., Mann, J., & 11 others, Apr 2021, In: Gastroenterology. 160, 5, p. 1725-1740.e2Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Liver injury in COVID-19 and IL-6 trans-signaling-induced endotheliopathy
McConnell, M. J., Kawaguchi, N., Kondo, R., Sonzogni, A., Licini, L., Valle, C., Bonaffini, P. A., Sironi, S., Alessio, M. G., Previtali, G., Seghezzi, M., Zhang, X., Lee, A. I., Pine, A. B., Chun, H. J., Zhang, X., Fernandez-Hernando, C., Qing, H., Wang, A., Price, C., & 5 others, Sep 2021, In: Journal of Hepatology. 75, 3, p. 647-658 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Pathological characteristics of liver sinusoidal thrombosis in COVID-19 patients: A series of 43 cases
Kondo, R., Kawaguchi, N., McConnell, M. J., Sonzogni, A., Licini, L., Valle, C., Bonaffini, P. A., Sironi, S., Alessio, M. G., Previtali, G., Seghezzi, M., Zhang, X., Sun, Z., Utsumi, T., Strazzabosco, M. & Iwakiri, Y., Sep 2021, In: Hepatology Research. 51, 9, p. 1000-1006 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis
Yang, Z., Zhang, T., Kusumanchi, P., Tang, Q., Sun, Z., Radaeva, S., Peiffer, B., Shah, V. H., Kamath, P., Gores, G. J., Sanyal, A., Chalasani, N., Jiang, Y., Huda, N., Ma, J. & Liangpunsakul, S., Nov 2021, In: Hepatology. 74, 5, p. 2436-2451 16 p.Research output: Contribution to journal › Article › peer-review
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2020
Butyric acid normalizes hyperglycemia caused by the tacrolimus-induced gut microbiota
Jiao, W., Zhang, Z., Xu, Y., Gong, L., Zhang, W., Tang, H., Zeng, S., Zhang, Q., Sun, Z., Liu, L. & Hu, X., Sep 1 2020, In: American Journal of Transplantation. 20, 9, p. 2413-2424 12 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis
Hyun, J., Sun, Z., Ahmadi, A. R., Bangru, S., Chembazhi, U. V., Du, K., Chen, T., Tsukamoto, H., Rusyn, I., Kalsotra, A. & Diehl, A. M., Apr 1 2020, In: Journal of Clinical Investigation. 130, 4, p. 2129-2145 17 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
ER stress-induced upregulation of NNMT contributes to alcohol-related fatty liver development
Song, Q., Chen, Y., Wang, J., Hao, L., Huang, C., Griffiths, A., Sun, Z., Zhou, Z. & Song, Z., Oct 2020, In: Journal of Hepatology. 73, 4, p. 783-793 11 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Major improvement in wound healing through pharmacologic mobilization of stem cells in severely diabetic rats
Qi, L., Ahmadi, A. R., Huang, J., Chen, M., Pan, B., Kuwabara, H., Iwasaki, K., Wang, W., Wesson, R., Cameron, A. M., Cui, S., Burdick, J. & Sun, Z., Apr 1 2020, In: Diabetes. 69, 4, p. 699-712 14 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Pancreatic volume does not correlate with histologic fibrosis in adult patients with recurrent acute and chronic pancreatitis
Faghih, M., Noë, M., Mannan, R., Kamel, I. R., Zaheer, A., Kalyani, R. R., Hall, E., Afghani, E., Warren, D., Desai, N., Sun, Z., Walsh, C., Makary, M. A., Goggins, M., Hruban, R. H., He, J. & Singh, V. K., Sep 2020, In: Pancreatology. 20, 6, p. 1078-1084 7 p.Research output: Contribution to journal › Article › peer-review
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Paneth Cell Dysfunction Mediates Alcohol-related Steatohepatitis Through Promoting Bacterial Translocation in Mice: Role of Zinc Deficiency
Zhong, W., Wei, X., Hao, L., Lin, T. D., Yue, R., Sun, X., Guo, W., Dong, H., Li, T., Ahmadi, A. R., Sun, Z., Zhang, Q., Zhao, J. & Zhou, Z., May 1 2020, In: Hepatology. 71, 5, p. 1575-1591 17 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Senescence of fibroblastic reticular cells in draining lymph nodes: Immunoregulation following transplantation
Sun, Z. & Burdick, J., Aug 3 2020, In: Journal of Clinical Investigation. 140, 8, p. 3965-3967 3 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Activation of BMP Signaling by FKBP12 Ligands Synergizes with Inhibition of CXCR4 to Accelerate Wound Healing
Peiffer, B. J., Qi, L., Ahmadi, A. R., Wang, Y., Guo, Z., Peng, H., Sun, Z. & Liu, J. O., May 16 2019, In: Cell Chemical Biology. 26, 5, p. 652-661.e4Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Mitochondrial membrane potential and delayed graft function following kidney transplantation
Garonzik-Wang, J. M., Lonze, B. E., Ruck, J. M., Luo, X., Massie, A. B., Melancon, K., Burdick, J. F., Segev, D. L. & Sun, Z., Feb 2019, In: American Journal of Transplantation. 19, 2, p. 585-590 6 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Orthotopic rat kidney transplantation: A novel and simplified surgical approach
Ahmadi, A. R., Qi, L., Iwasaki, K., Wang, W., Wesson, R. N., Cameron, A. M. & Sun, Z., May 2019, In: Journal of Visualized Experiments. 2019, 147, e59403.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Pharmacological Mobilization and Recruitment of Stem Cells in Rats Stops Abdominal Adhesions After Laparotomy
Iwasaki, K., Ahmadi, A. R., Qi, L., Chen, M., Wang, W., Katsumata, K., Tsuchida, A., Burdick, J., Cameron, A. M. & Sun, Z., Dec 1 2019, In: Scientific reports. 9, 1, 7149.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Phosphodiesterase 4 Inhibition as a Therapeutic Target for Alcoholic Liver Disease: From Bedside to Bench
Rodriguez, W. E., Wahlang, B., Wang, Y., Zhang, J., Vadhanam, M. V., Joshi-Barve, S., Bauer, P., Cannon, R., Ahmadi, A. R., Sun, Z., Cameron, A., Barve, S., Maldonado, C., McClain, C. & Gobejishvili, L., Dec 1 2019, In: Hepatology. 70, 6, p. 1958-1971 14 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Rapamycin-inspired macrocycles with new target specificity
Guo, Z., Hong, S. Y., Wang, J., Rehan, S., Liu, W., Peng, H., Das, M., Li, W., Bhat, S., Peiffer, B., Ullman, B. R., Tse, C. M., Tarmakova, Z., Schiene-Fischer, C., Fischer, G., Coe, I., Paavilainen, V. O., Sun, Z. & Liu, J. O., Mar 1 2019, In: Nature Chemistry. 11, 3, p. 254-263 10 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice
Kim, H. G., Huang, M., Xin, Y., Zhang, Y., Zhang, X., Wang, G., Liu, S., Wan, J., Ahmadi, A. R., Sun, Z., Liangpunsakul, S., Xiong, X. & Dong, X. C., Nov 2019, In: Journal of Hepatology. 71, 5, p. 960-969 10 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2018
Desensitization and prevention of antibody-mediated rejection in vascularized composite allotransplantation by syngeneic hematopoietic stem cell transplantation
Wang, H. D., Fidder, S. A. J., Miller, D. T., Furtmüller, G. J., Ahmadi, A. R., Nägele, F., Lopez, J., Quan, A., Budihardjo, J., Lough, D. M., Akpinarli, B., Etra, J. W., Vasilic, D., Raimondi, G., Lee, W. P. A., Montgomery, R. A., Sun, Z. & Brandacher, G., Apr 1 2018, In: Transplantation. 102, 4, p. 593-600 8 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Immunosuppressive effect of the gut microbiome altered by high-dose tacrolimus in mice
Zhang, Z., Liu, L., Tang, H., Jiao, W., Zeng, S., Xu, Y., Zhang, Q., Sun, Z., Mukherjee, A., Zhang, X. & Hu, X., Jul 2018, In: American Journal of Transplantation. 18, 7, p. 1646-1656 11 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Kupffer cells survive Plasmodium berghei sporozoite exposure and respond with a rapid cytokine release
Tweedell, R. E., Qi, L., Sun, Z. & Dinglasan, R., Dec 2018, In: Pathogens. 7, 4, 91.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Liver Transplantation for Severe Alcoholic Hepatitis, Updated Lessons from the World's Largest Series
Weeks, S. R., Sun, Z., McCaul, M. E., Zhu, H., Anders, R. A., Philosophe, B., Ottmann, S. E., Garonzik Wang, J. M., Gurakar, A. O. & Cameron, A. M., Apr 2018, In: Journal of the American College of Surgeons. 226, 4, p. 549-557 9 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Pharmacological Mobilization of Endogenous Bone Marrow Stem Cells Promotes Liver Regeneration after Extensive Liver Resection in Rats
Zhai, R., Wang, Y., Qi, L., Williams, G. M., Gao, B., Song, G., Burdick, J. F. & Sun, Z., Dec 1 2018, In: Scientific reports. 8, 1, 3587.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Role of A-Kinase Anchoring Protein Phosphorylation in Alcohol-Induced Liver Injury and Hepatic Stellate Cell Activation
Ramani, K., Tomasi, M. L., Berlind, J., Mavila, N. & Sun, Z., Mar 2018, In: American Journal of Pathology. 188, 3, p. 640-655 16 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Stem Cell Mobilization Is Lifesaving in a Large Animal Preclinical Model of Acute Liver Failure
Ahmadi, A. R., Chicco, M., Wesson, R. N., Anders, R. A., Dor, F. J. M. F., IJzermans, J. N. M., Creamer, T. J., Williams, G. M., Sun, Z. & Cameron, A. M., Oct 1 2018, In: Annals of surgery. 268, 4, p. 620-631 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2017
Chronic Gastrointestinal Dysmotility and Pain Following Total Pancreatectomy with Islet Autotransplantation for Chronic Pancreatitis
John, G. K., Singh, V. K., Moran, R. A., Warren, D., Sun, Z., Desai, N., Walsh, C., Kalyani, R. R., Hall, E., Hirose, K., Makary, M. A. & Stein, E. M., Apr 1 2017, In: Journal of Gastrointestinal Surgery. 21, 4, p. 622-627 6 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Fibrosis in small syngeneic rat liver grafts because of damaged bone marrow stem cells from chronic alcohol consumption
Hisada, M., Zhang, X., Ota, Y., Cameron, A. M., Burdick, J., Gao, B., Williams, G. M. & Sun, Z., Dec 2017, In: Liver Transplantation. 23, 12, p. 1564-1576 13 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Glycemic predictors of insulin independence after total pancreatectomy with islet autotransplantation
Quartuccio, M., Hall, E., Singh, V., Makary, M. A., Hirose, K., Desai, N., Walsh, C., Warren, D., Sun, Z., Stein, E. & Kalyani, R. R., Mar 1 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 3, p. 801-809 9 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Laparoscopic total pancreatectomy with islet autotransplantation and intraoperative islet separation as a treatment for patients with chronic pancreatitis
Fan, C. J., Hirose, K., Walsh, C. M., Quartuccio, M., Desai, N. M., Singh, V. K., Kalyani, R. R., Warren, D. S., Sun, Z., Hanna, M. N. & Makary, M. A., Jun 2017, In: JAMA surgery. 152, 6, p. 550-556 7 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Prevalence and predictors of pain and opioid analgesic use following total pancreatectomy with islet autotransplantation for pancreatitis
Moran, R. A., Klapheke, R., John, G. K., Devlin, S., Warren, D., Desai, N., Sun, Z., Walsh, C., Kalyani, R. R., Hall, E., Stein, E. M., Kalloo, A. N., Zaheer, A., Hirose, K., Makary, M. A. & Singh, V. K., Sep 2017, In: Pancreatology. 17, 5, p. 732-737 6 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
2016
Chimeric Allografts Induced by Short-Term Treatment With Stem Cell Mobilizing Agents Result in Long-Term Kidney Transplant Survival Without Immunosuppression: II, Study in Miniature Swine
Cameron, A. M., Wesson, R. N., Ahmadi, A. R., Singer, A. L., Hu, X., Okabayashi, T., Wang, Y., Shigoka, M., Fu, Y., Gao, W., Raccusen, L. C., Montgomery, R. A., Williams, G. M. & Sun, Z., Jul 1 2016, In: American Journal of Transplantation. 16, 7, p. 2066-2076 11 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations