Research output per year
Research output per year
- 29 results
Search results
-
2023
Editorial: GBM stem cells and the brain tumor microenvironment
Li, Y. & Abounader, R., 2023, In: Frontiers in Oncology. 13, 1153803.Research output: Contribution to journal › Editorial › peer-review
Open Access -
2022
ATRX loss promotes immunosuppressive mechanisms in IDH1 mutant glioma
Hu, C., Wang, K., Damon, C., Fu, Y., Ma, T., Kratz, L., Lal, B., Ying, M., Xia, S., Cahill, D. P., Jackson, C. M., Lim, M., Laterra, J. & Li, Y., Jun 1 2022, In: Neuro-oncology. 24, 6, p. 888-900 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting UDP-α-D-glucose 6-dehydrogenase alters the CNS tumor immune microenvironment and inhibits glioblastoma growth
Zhan, D., Yalcin, F., Ma, D., Fu, Y., Wei, S., Lal, B., Li, Y., Dzaye, O., Laterra, J., Ying, M., Lopez-Bertoni, H. & Xia, S., May 2022, In: Genes and Diseases. 9, 3, p. 717-730 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Egfr activates a taz-driven oncogenic program in glioblastoma
Gao, M., Fu, Y., Zhou, W., Gui, G., Lal, B., Li, Y., Xia, S., Ji, H., Eberhart, C. G., Laterra, J. & Ying, M., Jul 1 2021, In: Cancer Research. 81, 13, p. 3580-3592 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Frondoside a inhibits an MYC-driven medulloblastoma model derived from human-induced pluripotent stem cells
Xue, Y., Fu, Y., Zhao, F., Gui, G., Li, Y., Rivero-Hinojosa, S., Liu, G., Li, Y., Xia, S., Eberhart, C. G. & Ying, M., Jun 2021, In: Molecular cancer therapeutics. 20, 6, p. 1199-1209 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Monoallelic IDH1 R132H mutation mediates glioma cell response to anticancer therapies via induction of senescence
Zhan, D., Ma, D., Wei, S., Lal, B., Fu, Y., Eberhart, C., Laterra, J., Ying, M., Li, Y., Meeker, A., Lopez-Bertoni, H. & Xia, S., Nov 2021, In: Molecular Cancer Research. 19, 11, p. 1878-1888 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mutant IDH1 promotes phagocytic function of microglia/macrophages in gliomas by downregulating ICAM1
Ma, D., Zhan, D., Fu, Y., Wei, S., Lal, B., Wang, J., Li, Y., Lopez-Bertoni, H., Yalcin, F., Dzaye, O., Eberhart, C. G., Laterra, J., Wilson, M. A., Ying, M. & Xia, S., Oct 1 2021, In: Cancer Letters. 517, p. 35-45 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Reprogramming transcription factors Oct4 and Sox2 induce a BRD-dependent immunosuppressive transcriptome in GBM-propagating cells
Ma, T., Hu, C., Lal, B., Zhou, W., Ma, Y., Ying, M., Prinos, P., Quiñones-Hinojosa, A., Lim, M., Laterra, J. & Li, Y., May 1 2021, In: Cancer Research. 81, 9, p. 2457-2469 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
ShRNA-based POLD2 expression knockdown sensitizes glioblastoma to DNA-Damaging therapeutics
Xu, Q., Hu, C., Zhu, Y., Wang, K., Lal, B., Li, L., Tang, J., Wei, S., Huang, G., Xia, S., Lv, S., Laterra, J., Jiang, Y. & Li, Y., Jul 10 2020, In: Cancer Letters. 482, p. 126-135 10 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
2018
Crizotinib and erlotinib inhibits growth of c-Met+/EGFRvIII+ primary human glioblastoma xenografts
Goodwin, C. R., Rath, P., Oyinlade, O., Lopez, H., Mughal, S., Xia, S., Li, Y., Kaur, H., Zhou, X., Ahmed, A. K., Ho, S., Olivi, A. & Lal, B., Aug 2018, In: Clinical Neurology and Neurosurgery. 171, p. 26-33 8 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Heterozygous IDH1 R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP
Wei, S., Wang, J., Oyinlade, O., Ma, D., Wang, S., Kratz, L., Lal, B., Xu, Q., Liu, S., Shah, S. R., Zhang, H., Li, Y., Quiñones-Hinojosa, A., Zhu, H., Huang, Z. Y., Cheng, L., Qian, J. & Xia, S., Sep 20 2018, In: Oncogene. 37, 38, p. 5160-5174 15 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Oncogenic MicroRNA-20a is downregulated by the HIF-1α/c-MYC pathway in IDH1 R132H-mutant glioma
Xu, Q., Ahmed, A. K., Zhu, Y., Wang, K., Lv, S., Li, Y. & Jiang, Y., May 23 2018, In: Biochemical and Biophysical Research Communications. 499, 4, p. 882-888 7 p.Research output: Contribution to journal › Article › peer-review
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2016
Epigenetic modulation of a miR-296-5p:HMGA1 axis regulates Sox2 expression and glioblastoma stem cells
Lopez-Bertoni, H., Lal, B., Michelson, N., Guerrero-Cázares, H., Quinõnes-Hinojosa, A., Li, Y. & Laterra, J., Sep 15 2016, In: Oncogene. 35, 37, p. 4903-4913 11 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
2015
DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2
Lopez-Bertoni, H., Lal, B., Li, A., Caplan, M., Guerrero-Cázares, H., Eberhart, C. G., Quiñones-Hinojosa, A., Glas, M., Scheffler, B., Laterra, J. & Li, Y., Jul 23 2015, In: Oncogene. 34, 30, p. 3994-4004 11 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
2013
In vivo c-Met pathway inhibition depletes human glioma xenografts of tumor-propagating stem-like cells
Rath, P., Lal, B., Ajala, O., Li, Y., Xia, S., Kim, J. & Laterra, J., Apr 2013, In: Translational Oncology. 6, 2, p. 104-111 8 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
2012
Cancer stem cells: Distinct entities or dynamically regulated phenotypes?
Li, Y. & Laterra, J., Feb 1 2012, In: Cancer Research. 72, 3, p. 576-580 5 p.Research output: Contribution to journal › Review article › peer-review
Open Access154 Scopus citations -
EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase
Wang, S. D., Rath, P., Lal, B., Richard, J-P., Li, Y., Goodwin, C. R., Laterra, J. & Xia, S., Dec 13 2012, In: Oncogene. 31, 50, p. 5132-5143 12 p.Research output: Contribution to journal › Article › peer-review
56 Scopus citations -
2011
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
Li, Y., Li, A., Glas, M., Lal, B., Ying, M., Sang, Y., Xia, S., Trageser, D., Guerrero-Cázares, H., Eberhart, C. G., Quiñones-Hinojosa, A., Scheffler, B. & Laterra, J., Jun 14 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 24, p. 9951-9956 6 p.Research output: Contribution to journal › Article › peer-review
Open Access184 Scopus citations -
Krüppel-like family of transcription factor 9, a differentiation- associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem cells
Ying, M., Sang, Y., Li, Y., Guerrero-Cazares, H., Quinones-Hinojosa, A., Vescovi, A. L., Eberhart, C. G., Xia, S. & Laterra, J., Jan 2011, In: Stem Cells. 29, 1, p. 20-31 12 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
2010
microRNA-34a is tumor suppressive in brain tumors and glioma stem cells
Guessous, F., Zhang, Y., Kofman, A., Catania, A., Li, Y., Schiff, D., Purow, B. & Abounader, R., Mar 15 2010, In: Cell Cycle. 9, 6, p. 1031-1036 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
2009
Interactions between PTEN and the c-Met pathway in glioblastoma and implications for therapy
Li, Y., Guessous, F., Dipierro, C., Zhang, Y., Mudrick, T., Fuller, L., Johnson, E., Marcinkiewicz, L., Engelhardt, M., Kefas, B., Schiff, D., Kim, J. & Abounader, R., Feb 1 2009, In: Molecular cancer therapeutics. 8, 2, p. 376-385 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes
Yunqing, L., Guessous, F., Ying, Z., DiPierro, C., Kefas, B., Johnson, E., Marcinkiewicz, L., Jinmai, J., Yanzhi, Y., Schmittgen, T. D., Lopes, B., Schiff, D., Purow, B. & Abounader, R., Oct 1 2009, In: Cancer Research. 69, 19, p. 7569-7576 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The neuronal microRNA miR-326 acts in a feedback loop with Notch and has therapeutic potential against brain tumors
Kefas, B., Comeau, L., Floyd, D. H., Seleverstov, O., Godlewski, J., Schmittgen, T., Jiang, J., DiPierro, C. G., Li, Y., Chiocca, E. A., Lee, J., Fine, H., Abounader, R., Lawler, S. & Purow, B., Dec 2 2009, In: Journal of Neuroscience. 29, 48, p. 15161-15168 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2008
Functional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma
Li, Y., Guessous, F., Johnson, E. B., Eberhart, C. G., Li, X. N., Shu, Q., Fan, S., Lal, B., Laterra, J., Schiff, D. & Abounader, R., Feb 2008, In: Laboratory Investigation. 88, 2, p. 98-111 14 p.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
microRNA-7 inhibits the epidermal growth factor receptor and the akt pathway and is down-regulated in glioblastoma
Kefas, B., Godlewski, J., Comeau, L., Li, Y., Abounader, R., Hawkinson, M., Lee, J., Fine, H., Chiocca, E. A., Lawler, S. & Purow, B., May 15 2008, In: Cancer Research. 68, 10, p. 3566-3572 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations
Li, Y., Guessous, F., Kwon, S., Kumar, M., Ibidapo, O., Fuller, L., Johnson, E., Lal, B., Hussaini, I., Bao, Y., Laterra, J., Schiff, D. & Abounader, R., Mar 15 2008, In: Cancer Research. 68, 6, p. 1723-1731 9 p.Research output: Contribution to journal › Article › peer-review
Open Access72 Scopus citations -
Signaling pathways in medulloblastoma
Guessous, F., Li, Y. & Abounader, R., Dec 2008, In: Journal of Cellular Physiology. 217, 3, p. 577-583 7 p.Research output: Contribution to journal › Short survey › peer-review
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2005
The scatter factor/hepatocyte growth factor: c-Met pathway in human embryonal central nervous system tumor malignancy
Li, Y., Lal, B., Kwon, S., Fan, X., Saldanha, U., Reznik, T. E., Kuchner, E. B., Eberhart, C., Laterra, J. & Abounader, R., Oct 15 2005, In: Cancer Research. 65, 20, p. 9355-9362 8 p.Research output: Contribution to journal › Article › peer-review
Open Access81 Scopus citations -
2004
Cotreatment with Histone Deacetylase Inhibitor LAQ824 Enhances Apo-2L/ Tumor Necrosis Factor-Related Apoptosis Inducing Ligand-Induced Death Inducing Signaling Complex Activity and Apoptosis of Human Acute Leukemia Cells
Guo, F., Sigua, C., Tao, J., Bali, P., George, P., Li, Y., Wittmann, S., Moscinski, L., Atadja, P. & Bhalla, K., Apr 1 2004, In: Cancer Research. 64, 7, p. 2580-2589 10 p.Research output: Contribution to journal › Article › peer-review