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Yang Ding

Assistant Professor

20152025

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Collaborations and top research areas from the last five years

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  • A multiomic atlas identifies a treatment-resistant, bone marrow progenitor-like cell population in T cell acute lymphoblastic leukemia

    Xu, J., Chen, C., Sussman, J. H., Yoshimura, S., Vincent, T., Pölönen, P., Hu, J., Bandyopadhyay, S., Elghawy, O., Yu, W., Tumulty, J., Chen, C. H., Li, E. Y., Diorio, C., Shraim, R., Newman, H., Uppuluri, L., Li, A., Chen, G. M. & Wu, D. W. & 32 others, Ding, Y. Y., Xu, J. A., Karanfilovski, D., Lim, T., Hsu, M., Thadi, A., Ahn, K. J., Wu, C. Y., Peng, J., Sun, Y., Wang, A., Mehta, R., Frank, D., Meyer, L., Loh, M. L., Raetz, E. A., Chen, Z., Wood, B. L., Devidas, M., Dunsmore, K. P., Winter, S. S., Chang, T. C., Wu, G., Pounds, S. B., Zhang, N. R., Carroll, W., Hunger, S. P., Bernt, K., Yang, J. J., Mullighan, C. G., Tan, K. & Teachey, D. T., Jan 2025, In: Nature Cancer. 6, 1, p. 102-122 21 p., e150363.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

    Chen, C., Xu, J., Sussman, J. H., Vincent, T., Tumulty, J. S., Yoshimura, S., Alikarami, F., Yu, W., Ding, Y. Y., Chen, C. H., Li, E. Y., Yang, A., Qin, X., Bandyopadhyay, S., Peng, J., Pölönen, P., Newman, H., Wood, B. L., Hu, J. & Shraim, R. & 16 others, Hughes, A. D., Diorio, C., Uppuluri, L., Shi, G., Ryan, T., Fuller, T., Loh, M. L., Raetz, E. A., Hunger, S. P., Pounds, S. B., Mullighan, C. G., Frank, D., Yang, J. J., Bernt, K. M., Teachey, D. T. & Tan, K., Jun 5 2025, In: Blood. 145, 23, p. 2685-2700 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Targeting senescent stemlike subpopulations in Philadelphia chromosome–like acute lymphoblastic leukemia

    Ding, Y. Y., Sussman, J. H., Madden, K., Loftus, J. P., Chen, R. K., Falkenstein, C. D., Bárcenas López, D. A., Hottman, D. A., Mathier, B., Yu, W., Xu, J., Chen, C., Chen, C. H., He, B., Bandyopadhyay, S., Zhang, Z., Lee, D. G., Wang, H., Peng, J. & Dang, C. V. & 2 others, Tan, K. & Tasian, S. K., Mar 13 2025, In: Blood. 145, 11, p. 1195-1210 16 p.

    Research output: Contribution to journal › Article › peer-review

  • Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell–like blasts in KMT2A-rearranged leukemia

    Chen, C., Yu, W., Alikarami, F., Qiu, Q., Chen, C. H., Flournoy, J., Gao, P., Uzun, Y., Fang, L., Davenport, J. W., Hu, Y., Zhu, Q., Wang, K., Libbrecht, C., Felmeister, A., Rozich, I., Ding, Y. Y., Hunger, S. P., Felix, C. A. & Wu, H. & 5 others, Brown, P. A., Guest, E. M., Barrett, D. M., Bernt, K. M. & Tan, K., Apr 7 2022, In: Blood. 139, 14, p. 2198-2211 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Integrative bulk and single-cell profiling of premanufacture t-cell populations reveals factors mediating long-term persistence of car t-cell therapy

    Chen, G. M., Chen, C., Das, R. K., Gao, P., Chen, C. H., Bandyopadhyay, S., Ding, Y. Y., Uzun, Y., Yu, W., Zhu, Q., Myers, R. M., Grupp, S. A., Barrett, D. M. & Tan, K., Sep 2021, In: Cancer discovery. 11, 9, p. 2186-2199 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
View all 15 Research outputs