Research output per year
Research output per year
- 26 results
Search results
-
2023
SLC26A3 (DRA) is stimulated in a synergistic, intracellular Ca21-dependent manner by cAMP and ATP in intestinal epithelial cells
Sarker, R., Lin, R., Singh, V., Donowitz, M. & Tse, C. M., Jun 2023, In: American Journal of Physiology - Cell Physiology. 324, 6, p. C1263-C1273Research output: Contribution to journal › Article › peer-review
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The Air–Liquid Interface Reorganizes Membrane Lipids and Enhances the Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colonoid Monolayers
Tse, C. M., Zhang, Z., Lin, R., Sarker, R., Donowitz, M. & Singh, V., May 2023, In: International journal of molecular sciences. 24, 9, 8273.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Chronic Inflammation in Ulcerative Colitis Causes Long-Term Changes in Goblet Cell Function
Singh, V., Johnson, K., Yin, J., Lee, S., Lin, R., Yu, H., In, J., Foulke-Abel, J., Zachos, N. C., Donowitz, M. & Rong, Y., Jan 2022, In: CMGH. 13, 1, p. 219-232 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
mOrange2, a Genetically Encoded, pH Sensitive Fluorescent Protein, is an Alternative to BCECF-AM to Measure Intracellular pH to Determine NHE3 and DRA Activity
Sarker, R., Tse, C. M., Lin, R., McNamara, G., Singh, V. & Donowitz, M., 2022, In: Cellular Physiology and Biochemistry. 56, 1, p. 39-49 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity
Tse, C. M., Yin, J., Singh, V., Sarker, R., Lin, R., Verkman, A. S., Turner, J. R. & Donowitz, M., Jan 1 2019, In: CMGH. 7, 3, p. 641-653 13 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2018
Cholera toxin inhibits SNX27-retromer-mediated delivery of cargo proteins to the plasma membrane
Singh, V., Yang, J., Yin, J., Cole, R., Tse, M., Berman, D. E., Small, S. A., Petsko, G. & Donowitz, M., Aug 1 2018, In: Journal of cell science. 131, 16, jcs.218610.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers
Yin, J., Tse, C. M., Avula, L. R., Singh, V., Foulke-Abel, J., de Jonge, H. R. & Donowitz, M., 2018, In: CMGH. 5, 4, p. 591-609 19 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2017
PDZ domain-dependent regulation of NHE3 protein by both internal Class II and C-terminal Class i PDZ-binding motifs
Cha, B., Yang, J., Singh, V., Zachos, N. C., Sarker, R. I., Chen, T. E., Chakraborty, M., Tse, C. M. & Donowitz, M., May 19 2017, In: Journal of Biological Chemistry. 292, 20, p. 8279-8290 12 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2015
Cyclic GMP kinase II (cGKII) inhibits NHE3 by altering its trafficking and phosphorylating NHE3 at three required sites: Identification of a multifunctional phosphorylation site
Chen, T., Kocinsky, H. S., Cha, B., Murtazina, R., Yang, J., Tse, C. M., Singh, V., Cole, R., Aronson, P. S., De Jonge, H., Sarker, R. & Donowitz, M., Jan 23 2015, In: Journal of Biological Chemistry. 290, 4, p. 1952-1965 14 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3
Singh, V., Yang, J., Cha, B., Chen, T. E., Sarker, R., Yin, J., Avula, L. R., Tse, M. & Donowitz, M., Jun 1 2015, In: Molecular biology of the cell. 26, 11, p. 2030-2043 14 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2-ezrin binding and dexamethasone stimulated NHE3 activity
Yang, J., Sarker, R., Singh, V., Sarker, P., Yin, J., Chen, T. E., Chaerkady, R., Li, X., Tse, C. M. & Donowitz, M., Aug 15 2015, In: Biochemical Journal. 470, 1, p. 77-90 14 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2014
AKT and GSK-3 are necessary for direct ezrin binding to NHE3 as part of a C-terminal Stimulatory complex: Role of a novel Ser-rich NHE3 C-Terminal motif in NHE3 activity and trafficking
Singh, V., Lin, R., Yang, J., Cha, B., Sarker, R., Tse, C. M. & Donowitz, M., Feb 28 2014, In: Journal of Biological Chemistry. 289, 9, p. 5449-5461 13 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Lactobacillus acidophilus attenuates downregulation of DRA function and expression in inflammatory models
Singh, V., Kumar, A., Raheja, G., Anbazhagan, A. N., Priyamvada, S., Saksena, S., Jhandier, M. N., Gill, R. K., Alrefai, W. A., Borthakur, A. & Dudeja, P. K., Sep 15 2014, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 307, 6, p. G623-G631Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
NHERF2/NHERF3 protein heterodimerization and macrocomplex formation are required for the inhibition of NHE3 activity by carbachol
Yang, J., Singh, V., Chen, T. E., Sarker, R., Xiong, L., Cha, B., Jin, S., Li, X., Ming Tse, C., Zachos, N. C. & Donowitz, M., 2014, In: Journal of Biological Chemistry. 289, 29, p. 20039-20053 15 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: Stimulation of Na+ absorption
Singh, V., Yang, J., Chen, T. E., Zachos, N. C., Kovbasnjuk, O., Verkman, A. S. & Donowitz, M., Jan 2014, In: Clinical Gastroenterology and Hepatology. 12, 1, p. 27-31 5 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
2013
NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells
Yang, J., Singh, V., Cha, B., Chen, T. E., Sarker, R., Murtazina, R., Jin, S., Zachos, N. C., Patterson, G. H., Tse, C. M., Kovbasnjuk, O., Li, X. & Donowitz, M., Jun 7 2013, In: Journal of Biological Chemistry. 288, 23, p. 16960-16974 15 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Regulation of intestinal serotonin transporter expression via epigenetic mechanisms: Role of HDAC2
Gill, R. K., Kumar, A., Malhotra, P., Maher, D., Singh, V., Dudeja, P. K., Alrefai, W. & Saksena, S., Feb 15 2013, In: American Journal of Physiology - Cell Physiology. 304, 4, p. C334-C341Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
2012
Lactobacillus acidophilus upregulates intestinal NHE3 expression and function
Singh, V., Raheja, G., Borthakur, A., Kumar, A., Gill, R. K., Alakkam, A., Malakooti, J. & Dudeja, P. K., Dec 15 2012, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 303, 12, p. G1393-G1401Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2011
Upregulation of p-glycoprotein by probiotics in intestinal epithelial cells and in the dextran sulfate sodium model of colitis in mice
Saksena, S., Goyal, S., Raheja, G., Singh, V., Akhtar, M., Nazir, T. M., Alrefai, W. A., Gill, R. K. & Dudeja, P. K., Jun 2011, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 300, 6, p. G1115-G1123Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
2010
Lactobacillus acidophilus stimulates the expression of SLC26A3 via a transcriptional mechanism
Raheja, G., Singh, V., Ma, K., Boumendjel, R., Borthakur, A., Gill, R. K., Saksena, S., Alrefai, W. A., Ramaswamy, K. & Dudeja, P. K., Mar 2010, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 298, 3, p. G395-G401Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
The probiotic Lactobacillus plantarum counteracts TNF-α-induced downregulation of SMCT1 expression and function
Borthakur, A., Anbazhagan, A. N., Kumar, A., Raheja, G., Singh, V., Ramaswamy, K. & Dudeja, P. K., Oct 2010, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 299, 4, p. G928-G934Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
2009
Drug resistance pattern and clonality in H. pylori strains
Singh, V., Mishra, S., Maurya, P., Rao, G. R. K., Jain, A. K., Dixit, V. K., Gulati, A. K. & Nath, G., 2009, In: Journal of infection in developing countries. 3, 2, p. 130-136 7 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2008
Detection of Helicobacter pylori in stool specimens: comparative evaluation of nested PCR and antigen detection.
Mishra, S., Singh, V., Rao, G. R. K., Jain, A. K., Dixit, V. K., Gulati, A. K. & Nath, G., 2008, In: Journal of infection in developing countries. 2, 3, p. 206-210 5 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Detection of Helicobacter pylori using nested polymerase chain reaction in gastric biopsy samples
Mahajan, D., Jain, A., Singh, V., Jain, A. K., Rao, G. R. K. & Nath, G., 2008, In: Indian Journal of Clinical Biochemistry. 23, 3, p. 243-245 3 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Evaluation of nested PCR in detection of Helicobacter pylori targeting a highly conserved gene: HSP60
Singh, V., Mishra, S., Rao, G. R. K., Jain, A. K., Dixit, V. K., Gulati, A. K., Mahajan, D., McClelland, M. & Nath, G., Feb 2008, In: Helicobacter. 13, 1, p. 30-34 5 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Prevalence of Helicobacter pylori in asymptomatic subjects-A nested PCR based study
Mishra, S., Singh, V., Rao, G. R. K., Dixit, V. K., Gulati, A. K. & Nath, G., Dec 2008, In: Infection, Genetics and Evolution. 8, 6, p. 815-819 5 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations