Pharmacology, Toxicology and Pharmaceutical Science
Glutamate Carboxypeptidase II
100%
Glutamic Acid
74%
Amino Acid Oxidase
62%
Glutaminase
53%
Oxidoreductase Inhibitor
48%
Glutamate Carboxypeptidase II Inhibitor
47%
Mouse
35%
Glutaric Acid
34%
Neuropathic Pain
31%
Pharmacokinetics
27%
Serine
25%
Dextro Serine
23%
Glutamine
23%
G Protein Coupled Receptor
20%
Prodrug
20%
Hydroxamic Acid
20%
Dextro Amino Acid Oxidase
20%
IC50
20%
Structure Activity Relationship
19%
Folic Acid
18%
Thiol
18%
Benzoic Acid
17%
High-Throughput Screening
17%
Methotrexate
16%
Haplorhini
15%
Neurologic Disease
14%
Alanine
13%
Sphingomyelin Phosphodiesterase
13%
Aspartic Acid
12%
Glutamate Synthase
11%
Malignant Neoplasm
11%
Neuroprotective Agent
11%
Catalytic Antibody
10%
Mouse Model
9%
Phosphinic Acid Derivative
9%
Carboxamide
9%
Diabetes Mellitus
9%
Phosphonate
8%
Disease
8%
Isocitrate Dehydrogenase 1
8%
Tetrahydrofolate Synthase
8%
Amyotrophic Lateral Sclerosis
8%
Thiophene
8%
Biological Activity
8%
Carboxylate
8%
Knockout Mouse
8%
Chemotherapy
7%
Acute Myeloid Leukemia
7%
Folic Acid Antagonist
7%
Neoplasm
7%
Keyphrases
Glutamate Carboxypeptidase II (GCPII)
54%
D-amino Acid Oxidase Activator
50%
Synthetic Evaluation
34%
D-amino Acid Oxidase
29%
Glutaminase 1 (GLS1)
28%
Glutamate
26%
Biological Evaluation
20%
Neutral Sphingomyelinase
20%
BPTES
20%
Glutaminase Inhibitor
18%
Glutamine
16%
Isoxazol
15%
Allosteric Inhibitor
14%
Oral Administration
14%
Thiadiazol
14%
Diazo
13%
Dizocilpine
13%
Chloro
13%
Prepulse Inhibition Deficit
13%
Prodrug
13%
Pharmacological Evaluation
13%
Hydroxamate
13%
NAALADase
13%
Design Evaluation
13%
Ethyl
12%
Glutamate Synthase (GOGAT)
11%
Primary Sensory Neurons
11%
Neuropathic Pain
11%
Small Molecules
11%
Extracellular Vesicles
10%
Knock-in Mouse Model
10%
CB-839
10%
Sulfide
9%
Small Molecule Inhibitors
9%
Thiols
9%
Glutamine Antagonist
9%
Plasma Parameters
9%
Benzo
9%
Ceramide
9%
Pharmacokinetics
8%
Metabolic Stability
8%
Drug Target
8%
Enantiospecificity
8%
Orally Bioavailable
8%
Clinical Development
8%
Brain Penetrant
8%
Mouse Model
8%
Kidney
8%
Schizophrenia
8%
IC50
8%
Biochemistry, Genetics and Molecular Biology
Glutaminase
50%
Glutamine
38%
Small Molecule
36%
Glutamate Carboxypeptidase II
34%
Enzyme
28%
Metabolic Pathway
17%
Cancer Cell
14%
Anabolism
14%
Folic Acid
14%
Argininosuccinate Synthetase 1
13%
High Throughput Screening
13%
D-Amino Acid Oxidase
13%
Dipeptide
12%
Enzymatic Hydrolysis
11%
Antifolate
11%
Metabolite
9%
Infrared Radiation
9%
Ceramide
8%
Anticancer
8%
Upregulation
8%
Isocitrate Dehydrogenase
8%
Amino Acids
7%
Tumor Progression
7%
Biological Activity
7%
Peptidomimetic
6%
Arginine Deiminase
6%
Serine
6%
Nucleophilicity
6%
Arginine
6%
Sphingolipid
6%
Anaplerosis
6%
Genetics
6%
Glucuronidation
6%
Substrate Analog
6%
Thiophene
6%
Myeloid
6%
Catalytic Antibody
6%
Macrophage
6%
Warburg Effect
6%
Agonist
6%
Acid Sphingomyelinase
6%
Sphingomyelin Phosphodiesterase
6%
Canavan Disease
6%
Polyglutamylation
6%
T Cell
6%
N-Acetyltransferase
6%
Methotrexate
6%
Histone Deacetylase
6%
Cytokine
6%
Monoclonal Antibody
6%