Research output per year
Research output per year
Search results
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2025
Diagnostic and Prognostic/Therapeutic Significance of Comprehensive Analysis of Bone and Soft Tissue Tumors Using Optical Genome Mapping and Next-Generation Sequencing
Ghabrial, J., Stinnett, V., Ribeiro, E., Klausner, M., Morsberger, L., Long, P., Middlezong, W., Xian, R., Gocke, C., Lin, M. T., Rooper, L., Baraban, E., Argani, P., Pallavajjala, A., Murry, J., Gross, J. M. & Zou, Y. S., Apr 2025, In: Modern Pathology. 38, 4, 100684.Research output: Contribution to journal › Article › peer-review
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2024
1q jumping translocation as a biomarker in myeloid malignancy: frequently mutated genes associated with bad prognosis and low survival
Halper-Stromberg, E., Stinnett, V., Morsberger, L., Pallavajjala, A., Levis, M. J., DeZern, A. E., Lei, M., Phan, B., Xian, R. R., Gocke, C. D., Tang, G. & Zou, Y. S., Dec 2024, In: Experimental Hematology and Oncology. 13, 1, 73.Research output: Contribution to journal › Letter › peer-review
Open Access -
A comprehensive approach to evaluate genetic abnormalities in multiple myeloma using optical genome mapping
Zou, Y. S., Klausner, M., Ghabrial, J., Stinnett, V., Long, P., Morsberger, L., Murry, J. B., Beierl, K., Gocke, C. D., Xian, R. R., Toomer, K. H., Ye, J. C., Orlowski, R. Z., Huff, C. A., Ali, S. A., Imus, P. H., Gocke, C. B. & Tang, G., Dec 2024, In: Blood cancer journal. 14, 1, 78.Research output: Contribution to journal › Letter › peer-review
Open Access -
A Precision Oncology Platform to Support Genotype-Tailored Therapy Selection
Botsis, T., Spiker, J., Kreimeyer, K., Fatteh, M., Wehr, J., Najjar, M., Tao, J., Xian, R., Imamovic, N. L., Pindzola, A., Dobs, A., Canzoniero, J. & Anagnostou, V., Aug 22 2024, Digital Health and Informatics Innovations for Sustainable Health Care Systems - Proceedings of MIE 2024. Mantas, J., Hasman, A., Demiris, G., Saranto, K., Marschollek, M., Arvanitis, T. N., Ognjanovic, I., Benis, A., Gallos, P., Zoulias, E. & Andrikopoulou, E. (eds.). IOS Press BV, p. 1854-1855 2 p. (Studies in Health Technology and Informatics; vol. 316).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Open Access -
A proteome-wide analysis unveils a core Epstein–Barr virus antibody signature of classic Hodgkin lymphoma across ethnically diverse populations
Sarathkumara, Y. D., Xian, R. R., Liu, Z., Yu, K. J., Chan, J. K. C., Kwong, Y. L., Lam, T. H., Liang, R., Chiu, B., Xu, J., Hu, W., Ji, B. T., Coghill, A. E., Kelly, A. M., Pfeiffer, R. M., Rothman, N., Ambinder, R. F., Hildesheim, A., Lan, Q. & Proietti, C. & 1 others, , Oct 15 2024, In: International Journal of Cancer. 155, 8, p. 1476-1486 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular Pathology of Mature Lymphoid Malignancies
Ware, A. D., Davis, K. & Xian, R. R., Jun 2024, In: Clinics in laboratory medicine. 44, 2, p. 355-376 22 p.Research output: Contribution to journal › Review article › peer-review
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Poly (ADP-ribose) Polymerase Inhibitor Resistance Driven by Emergence of Polyclonal Mutations With Convergent Evolution: A Molecular Tumor Board Discussion
Johns Hopkins Molecular Tumor Board, Oct 1 2024, In: JCO Precision Oncology. 8, e2400254.Research output: Contribution to journal › Article › peer-review
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Real-world treatment outcomes for Hodgkin lymphoma in South Africa: a prospective observational study
Vogt, S. L., Laudin, G., Zahurak, M., Vaughan, J., Lakha, A., Pather, S., Waja, Z., Chetty, D., Omar, T., Stevens, W., Ashmore, P., Otwombe, K., Hlongwane, K., Varadhan, R., Patel, M., Ambinder, R. F., Martinson, N. A., Xian, R. R. & Philip, V., Dec 2024, In: Infectious Agents and Cancer. 19, 1, 46.Research output: Contribution to journal › Article › peer-review
Open Access -
Sir Michael Anthony Epstein (1921-2024)
Ambinder, R. F. & Xian, R. R., Apr 19 2024, In: Science (New York, N.Y.). 384, 6693, p. 274 1 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The Era of Molecular Hematopathology: Back to the Future
Association for Molecular Pathology Hematopathology Subdivision Leadership, Nov 2024, In: Journal of Molecular Diagnostics. 26, 11, p. 945-949 5 p.Research output: Contribution to journal › Editorial › peer-review
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2023
A New Landscape of Testing and Therapeutics in Metastatic Breast Cancer
Jagannathan, G., White, M. J., Xian, R. R., Emens, L. A. & Cimino-Mathews, A., Jun 2023, In: Clinics in laboratory medicine. 43, 2, p. 299-321 23 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Cell-Free Circulating Tumor DNA and Epstein-Barr Virus DNA for Early Diagnosis of Epstein-Barr Virus-Associated Cancers
Xian, R. R. & Ambinder, R. F., Sep 10 2023, In: Journal of Clinical Oncology. 41, 26, p. 4290-4292 3 p.Research output: Contribution to journal › Article › peer-review
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Clinical Testing for Tumor Cell-Free DNA College of American Pathologists Proficiency Programs Reveal Practice Trends
Devereaux, K. A., Souers, R. J., Merker, J. D., Lindeman, N. I., Graham, R. P., Hameed, M. R., Vasalos, P., Moncur, J. T., Lockwood, C. M. & Xian, R. R., Apr 2023, In: Archives of Pathology and Laboratory Medicine. 147, 4, p. 425-433 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Colorectal cancer in patients of advanced age is associated with increased incidence of BRAF p.V600E mutation and mismatch repair deficiency
Christenson, E. S., Tsai, H. L., Le, D. T., Jaffee, E. M., Dudley, J., Xian, R. R., Gocke, C. D., Eshleman, J. R. & Lin, M. T., 2023, In: Frontiers in Oncology. 13, 1193259.Research output: Contribution to journal › Article › peer-review
Open Access -
Co-occurring mutations in ASXL1, SRSF2, and SETBP1 define a subset of myelodysplastic/ myeloproliferative neoplasm with neutrophilia
Jain, T., Ware, A. D., Dalton, W. B., Pasca, S., Tsai, H. L., Gocke, C. D., Gondek, L. P., Xian, R. R., Borowitz, M. J. & Levis, M. J., Aug 2023, In: Leukemia Research. 131, 107345.Research output: Contribution to journal › Article › peer-review
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Current clinical practices and challenges in molecular testing: a GOAL Consortium Hematopathology Working Group report
Lee, T. D., Aisner, D. L., David, M. P., Eno, C. C., Gagan, J., Gocke, C. D., Guseva, N. V., Haley, L., Jajosky, A. N., Jones, D., Mansukhani, M. M., Mroz, P., Murray, S. S., Newsom, K. J., Paulson, V., Roy, S., Rushton, C., Segal, J. P., Senaratne, T. N. & Siddon, A. J. & 6 others, , Aug 16 2023, In: Blood Advances. 7, 16, p. 4599-4607 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Diagnosis and monitoring of virus-associated cancer using cell-free DNA
Scholte, L. L., Bethony, J. M. & Xian, R. R., Jun 2023, In: Current Opinion in Virology. 60, 101331.Research output: Contribution to journal › Review article › peer-review
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Donor cell-derived genetic abnormalities after sex mismatched allogeneic cell transplantation: a unique challenge of donor cell leukemia
Klausner, M., Phan, B., Morsberger, L., Parish, R., Shane, A., Park, R., Gocke, C. D., Xian, R. R., Jones, R. J., Bolaños-Meade, J., Gondek, L. P., Phan, M. & Zou, Y. S., Dec 2023, In: Blood cancer journal. 13, 1, 163.Research output: Contribution to journal › Letter › peer-review
Open Access -
How to classify risk based on clinical and molecular modeling: integrating molecular markers in the risk assessment of myelodysplastic syndrome
Xian, R. R., Dec 8 2023, In: Hematology. American Society of Hematology. Education Program. 2023, 1, p. 51-58 8 p.Research output: Contribution to journal › Article › peer-review
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The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring
Batool, S. M., Yekula, A., Khanna, P., Hsia, T., Gamblin, A. S., Ekanayake, E., Escobedo, A. K., You, D. G., Castro, C. M., Im, H., Kilic, T., Garlin, M. A., Skog, J., Dinulescu, D. M., Dudley, J., Agrawal, N., Cheng, J., Abtin, F., Aberle, D. R. & Chia, D. & 28 others, , Oct 17 2023, In: Cell Reports Medicine. 4, 10, 101198.Research output: Contribution to journal › Review article › peer-review
Open Access -
2022
A New Landscape of Testing and Therapeutics in Metastatic Breast Cancer
Jagannathan, G., White, M. J., Xian, R. R., Emens, L. A. & Cimino-Mathews, A., Mar 2022, In: Surgical Pathology Clinics. 15, 1, p. 105-120 16 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
Fischer, C. G., Pallavajjala, A., Jiang, L. Q., Anagnostou, V., Tao, J., Adams, E., Eshleman, J. R., Gocke, C. D., Lin, M. T., Platz, E. A. & Xian, R. R., Jun 1 2022, In: Clinical Cancer Research. 28, 11, p. 2361-2372 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Case Report: Hematologic Recovery Following Stereotactic Ablative Radiotherapy in a Patient With Early-Stage Non-Small Cell Lung Cancer and Paraneoplastic Myelofibrosis
Sloan, L., Naik, R. P., Umrau, K., Xian, R. R., Marrone, K. A. & Voong, K. R., Feb 24 2022, In: Frontiers in Oncology. 12, 842620.Research output: Contribution to journal › Article › peer-review
Open Access -
Double PIK3CA Alterations and Parallel Evolution in Colorectal Cancers
Lin, M. T., Zheng, G., Rodriguez, E., Tseng, L. H., Parini, V., Xian, R., Zou, Y., Gocke, C. D. & Eshleman, J. R., Feb 1 2022, In: American journal of clinical pathology. 157, 2, p. 244-251 8 p.Research output: Contribution to journal › Article › peer-review
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Significance of lymph node fine needle aspiration for the diagnosis of HIV-associated lymphoma in a low-resource setting
Vogt, S. L., Maloma, L., Xian, R. R., Ambinder, R. F., Philip, V., Patel, M., Martinson, N. A. & Omar, T., Aug 1 2022, In: AIDS. 36, 10, p. 1393-1398 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Tiered Somatic Variant Classification Adoption Has Increased Worldwide With Some Practice Differences Based on Location and Institutional Setting A Study From the College of American Pathologists Molecular Oncology Committee
Bruehl, F. K., Kim, A. S., Li, M. M., Lindeman, N. I., Moncur, J. T., Souers, R. J., Vasalos, P., Voelkerding, K. V., Xian, R. R. & Surrey, L. F., Jul 2022, In: Archives of Pathology and Laboratory Medicine. 146, 7, p. 822-832 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
CloneRetriever: An Automated Algorithm to Identify Clonal B and T Cell Gene Rearrangements by Next-Generation Sequencing for the Diagnosis of Lymphoid Malignancies
Halper-Stromberg, E., McCall, C. M., Haley, L. M., Lin, M. T., Vogt, S., Gocke, C. D., Eshleman, J. R., Stevens, W., Martinson, N. A., Epeldegui, M., Holdhoff, M., Bettegowda, C., Glantz, M. J., Ambinder, R. F. & Xian, R. R., Nov 1 2021, In: Clinical chemistry. 67, 11, p. 1524-1533 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Feasibility of cell-free DNA collection and clonal immunoglobulin sequencing in South African patients with HIV-associated lymphoma
Vogt, S. L., Patel, M., Lakha, A., Philip, V., Omar, T., Ashmore, P., Pather, S., Haley, L. M., Zheng, G., Stone, J., Mayne, E., Stevens, W., Wagner-Johnston, N., Gocke, C. D., Martinson, N. A., Ambinder, R. F. & Xian, R. R., 2021, In: JCO Global Oncology. 7, p. 611-621 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
IDH1 and IDH2 Mutations in Colorectal Cancers
Huang, J., Tseng, L. H., Parini, V., Lokhandwala, P., Pallavajjala, A., Rodriguez, E., Xian, R., Chen, L. L., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Nov 1 2021, In: American journal of clinical pathology. 156, 5, p. 777-786 10 p.Research output: Contribution to journal › Article › peer-review
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Molecular Pathology of Mature Lymphoid Malignancies
Ware, A. D., Davis, K. & Xian, R. R., Sep 2021, In: Surgical Pathology Clinics. 14, 3, p. 529-547 19 p.Research output: Contribution to journal › Review article › peer-review
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Plasma EBV DNA: A Promising Diagnostic Marker for Endemic Burkitt Lymphoma
Xian, R. R., Kinyera, T., Otim, I., Sampson, J. N., Nabalende, H., Legason, I. D., Stone, J., Ogwang, M. D., Reynolds, S. J., Kerchan, P., Bhatia, K., Goedert, J. J., Mbulaiteye, S. M. & Ambinder, R. F., Dec 14 2021, In: Frontiers in Oncology. 11, 804083.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Clonal Origin Evaluated by Trunk and Branching Drivers and Prevalence of Mutations in Multiple Lung Tumor Nodules
Rodriguez, E. F., Tseng, L. H., De Marchi, F., Haung, J., Belchis, D., Xian, R., Gocke, C. D., Eshleman, J. R., Illei, P. B. & Lin, M. T., Aug 1 2020, In: Molecular Diagnosis and Therapy. 24, 4, p. 461-472 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
CpG methylation in cell-free Epstein-Barr virus DNA in patients with EBV-hodgkin lymphoma
Shamay, M., Kanakry, J. A., Low, J. S. W., Horowitz, N. A., Journo, G., Ahuja, A., Eran, Y., Barzilai, E., Dann, E. J., Stone, J., Woo, W. L., Hsieh, W.-S., Xian, R. R. & Ambinder, R. F., Apr 28 2020, In: Blood Advances. 4, 8, p. 1624-1627 4 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
CREBBP and STAT6 co-mutation and 16p13 and 1p36 loss define the t(14;18)-negative diffuse variant of follicular lymphoma
Xian, R. R., Xie, Y., Haley, L. M., Yonescu, R., Pallavajjala, A., Pittaluga, S., Jaffe, E. S., Duffield, A. S., McCall, C. M., Gheith, S. M. F. & Gocke, C. D., Jun 1 2020, In: Blood cancer journal. 10, 6, 69.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
IDH1 and IDH2 mutations in lung adenocarcinomas: Evidences of subclonal evolution
Rodriguez, E. F., De Marchi, F., Lokhandwala, P. M., Belchis, D., Xian, R., Gocke, C. D., Eshleman, J. R., Illei, P. & Li, M. T., Jun 1 2020, In: Cancer medicine. 9, 12, p. 4386-4394 9 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Proficiency testing of standardized samples shows high interlaboratory agreement for clinical next-generation sequencing-based hematologic malignancy assays with survey material-specific differences in variant frequencies
Keegan, A., Bridge, J. A., Lindeman, N. I., Long, T. A., Merker, J. D., Moncur, J. T., Montgomery, N. D., Nagarajan, R., Rothberg, P. G., Routbort, M. J., Vasalos, P., Xian, R. & Kim, A. S., Aug 2020, In: Archives of Pathology and Laboratory Medicine. 144, 8, p. 959-966 8 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Tetraploid Partial Hydatidiform Moles: Molecular Genotyping and Determination of Parental Contributions
Bynum, J., Batista, D., Xian, R., Xing, D., Eshleman, J. R., Ronnett, B. M. & Zheng, G., Jan 2020, In: Journal of Molecular Diagnostics. 22, 1, p. 90-100 11 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2019
An overview of DNA analytical methods
Arboleda, V. A. & Xian, R. R., 2019, Methods in Molecular Biology. Humana Press Inc., p. 385-402 18 p. (Methods in Molecular Biology; vol. 1897).Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Scopus citations -
Clinical validation of coexisting driver mutations in colorectal cancers
Zheng, G., Tseng, L. H., Haley, L., Ibrahim, J., Bynum, J., Xian, R., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Apr 2019, In: Human pathology. 86, p. 12-20 9 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Clinical Validation of Discordant Trunk Driver Mutations in Paired Primary and Metastatic Lung Cancer Specimens
Tseng, L. H., De Marchi, F., Pallavajjalla, A., Rodriguez, E., Xian, R., Belchis, D., Gocke, C. D., Eshleman, J. R., Illei, P. & Lin, M. T., Oct 7 2019, In: American journal of clinical pathology. 152, 5, p. 570-581 12 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Next-Generation Sequencing Analysis in Posttransplant Relapsed Acute Myeloid Leukemia Reveals Clonal Evolution and Donor-Derived Germline Variant Indicating Bone Marrow Chimerism
Kroloff, M. J., Crane, G. M., Press, R. D., Lee, S., Larson, S. M. & Xian, R. R., Nov 1 2019, In: AJSP: Reviews and Reports. 24, 6, p. 260-262 3 p.Research output: Contribution to journal › Article › peer-review
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Nucleic acid extraction from human biological samples
Mullegama, S. V., Alberti, M. O., Au, C., Li, Y., Toy, T., Tomasian, V. & Xian, R. R., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 359-383 25 p. (Methods in Molecular Biology; vol. 1897).Research output: Chapter in Book/Report/Conference proceeding › Chapter
6 Scopus citations -
2018
Electric Field–Induced Release and Measurement Liquid Biopsy for Noninvasive Early Lung Cancer Assessment
Wei, F., Strom, C. M., Cheng, J., Lin, C. C., Hsu, C. Y., Soo Hoo, G. W., Chia, D., Kim, Y., Li, F., Elashoff, D., Grognan, T., Tu, M., Liao, W., Xian, R., Grody, W. W., Su, W. C. & Wong, D. T. W., Nov 2018, In: Journal of Molecular Diagnostics. 20, 6, p. 738-742 5 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2016
Lack of TERT promoter mutations in human B-cell non-Hodgkin lymphoma
Lam, G., Xian, R. R., Li, Y., Burns, K. H. & Beemon, K. L., Nov 2016, In: Genes. 7, 11, 93.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Primary central nervous system gamma delta cytotoxic T-cell lymphoma
Mooney, K. L., Choy, W., Woodard, J., Xian, R. R., Deal, T. M., Kendle, R. F., Said, J., Grody, W. & Yang, I., Apr 1 2016, In: Journal of Clinical Neuroscience. 26, p. 138-140 3 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Primary salivary duct carcinoma of the lung, mucin-rich variant
Fishbein, G. A., Grimes, B. S., Xian, R. R., Lee, J. M., Barjaktarevic, I. & Xu, H., Jan 1 2016, In: Human pathology. 47, 1, p. 150-156 7 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2014
Mesothelin expression is associated with poor outcomes in breast cancer
Li, Y. R., Xian, R. R., Ziober, A., Conejo-Garcia, J., Perales-Puchalt, A., June, C. H., Zhang, P. J. & Tchou, J., Sep 24 2014, In: Breast Cancer Research and Treatment. 147, 3, p. 675-684 10 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Primary effusion lymphoma presenting as a cutaneous intravascular lymphoma
Crane, G. M., Xian, R. R., Burns, K. H., Borowitz, M. J., Duffield, A. S. & Taube, J. M., Dec 1 2014, In: Journal of cutaneous pathology. 41, 12, p. 928-935 8 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2012
Endoscopic ultrasound and endobronchial ultrasound-guided fine-needle aspiration of deep-seated lymphadenopathy: Analysis of 1338 cases
Nunez, A. L., Jhala, N. C., Carroll, A. J., Mikhail, F. M., Reddy, V. V. B., Xian, R. R. & Jhala, D. N., 2012, In: CytoJournal. 9, 1, A14.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Phage display generation of a novel human anti-CD1A monoclonal antibody with potent cytolytic activity
Bechan, G. I., Lee, D. W., Zajonc, D. M., Heckel, D., Xian, R., Throsby, M., van Meijer, M., Germeraad, W. T. V., Kruisbeek, A. M., Egeler, R. M. & Arceci, R. J., Nov 2012, In: British journal of haematology. 159, 3, p. 299-310 12 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations