Peter Abadir

2025

What drives older adults’ acceptance of virtual humans? A conjoint and latent class analysis on virtual exercise coach attributes for a community-based exercise program

Dino, M. J. S., Dion, K. W., Abadir, P. M., Budhathoki, C., Huang, C. M., Padula, W. V., Ong, I., Dennison Himmelfarb, C. R., Davidson, P. M. & Thiamwong, L., Mar 2025, In: Computers in Human Behavior. 164, 108507.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Artificial intelligence and technology collaboratories: Empowering innovation in AI + AgeTech

Li, R. M., Abadir, P. M., Battle, A., Chellappa, R., Choudhry, N. K., Demiris, G., Ganesan, D., Karlawish, J., Moore, J. H. & Walston, J. D., May 2024, In: Journal of the American Geriatrics Society. 72, 5, p. 1602-1604 3 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

Artificial Intelligence and Technology Collaboratories: Innovating aging research and Alzheimer's care

Abadir, P., Oh, E., Chellappa, R., Choudhry, N., Demiris, G., Ganesan, D., Karlawish, J., Marlin, B., Li, R. M., Dehak, N., Arbaje, A., Unberath, M., Cudjoe, T., Chute, C., Moore, J. H., Phan, P., Samus, Q., Schoenborn, N. L., Battle, A. & Walston, J. D., Apr 2024, In: Alzheimer's and Dementia. 20, 4, p. 3074-3079 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Artificial Intelligence in Geriatrics: Riding the Inevitable Tide of Promise, Challenges, and Considerations

Abadir, P. & Chellappa, R., Feb 1 2024, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 79, 2, 279.

Research output: Contribution to journal › Editorial › peer-review

Co-Delivery of Valsartan and Metformin from a Thermosensitive Hydrogel-Nanoparticle System Promotes Collagen Production in Proliferating and Senescent Primary Human Dermal Fibroblasts

Kuhn, P. M., Chen, S., Venkatraman, A., Abadir, P. M., Walston, J. D. & Kokkoli, E., Sep 9 2024, In: Biomacromolecules. 25, 9, p. 5702-5717 16 p.

Research output: Contribution to journal › Article › peer-review

Dual treatment with kynurenine pathway inhibitors and NAD⁺ precursors synergistically extends life span in Drosophila

Gabrawy, M. M., Westbrook, R., King, A., Khosravian, N., Ochaney, N., DeCarvalho, T., Wang, Q., Yu, Y., Huang, Q., Said, A., Abadir, M., Zhang, C., Khare, P., Fairman, J. E., Le, A., Milne, G. L., Vonhoff, F. J., Walston, J. D. & Abadir, P. M., Apr 2024, In: Aging Cell. 23, 4, e14102.

Research output: Contribution to journal › Article › peer-review

Open Access

Enhancing Care for Older Adults and Dementia Patients With Large Language Models: Proceedings of the National Institute on Aging-Artificial Intelligence & Technology Collaboratory for Aging Research Symposium

Abadir, P. M., Battle, A., Walston, J. D. & Chellappa, R., Sep 1 2024, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 79, 9, glae176.

Research output: Contribution to journal › Article › peer-review

Evaluation and mitigation of cognitive biases in medical language models

Schmidgall, S., Harris, C., Essien, I., Olshvang, D., Rahman, T., Kim, J. W., Ziaei, R., Eshraghian, J., Abadir, P. & Chellappa, R., Dec 2024, In: npj Digital Medicine. 7, 1, 295.

Research output: Contribution to journal › Article › peer-review

Open Access

Geriatric research through the lens of AGS/NIA U13: Two decades of interdisciplinary dialogues that have propelled the field

Abadir, P. & Whitson, H., May 2024, In: Journal of the American Geriatrics Society. 72, 5, p. 1623-1626 4 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

Mixed reality technology for older adults: Evaluating the impact of a novel virtual humanoid coach in a community-based physical exercise program in the Philippines

Dino, M. J. S., Dion, K. W., Abadir, P. M., Budhathoki, C., Huang, C. M., Ong, I., Vital, J. C., Cotter, V. T., Himmelfarb, C. R. D. & Davidson, P. M., Jul 1 2024, In: Health informatics journal. 30, 3

Research output: Contribution to journal › Article › peer-review

Open Access

Perspectives from Rising Stars at the R13 NIA/AGS Conference on Resilience Biomarkers

Umoh, M. E., Garcia-Contreras, M., Cheung, K. L. & Abadir, P., 2024, (Accepted/In press) In: Journal of the American Geriatrics Society.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Stress tests and biomarkers of resilience: Proceedings of the second state of resilience science conference

Colón-Emeric, C., Walston, J., Bartolomucci, A., Carroll, J., Picard, M., Salmon, A., Suglia, S., Whitson, H. & Abadir, P., 2024, (Accepted/In press) In: Journal of the American Geriatrics Society.

Research output: Contribution to journal › Article › peer-review

Open Access

The impact of a mixed reality technology-driven health enhancing physical activity program among community-dwelling older adults: a study protocol

Dino, M. J. S., Dion, K. W., Abadir, P. M., Budhathoki, C., Huang, C. M., Padula, W. V., Himmelfarb, C. R. D. & Davidson, P. M., 2024, In: Frontiers in Public Health. 12, 1383407.

Research output: Contribution to journal › Article › peer-review

Open Access

Unlocking the protective potential of the angiotensin type 2 receptor (AT₂R) in acute lung injury and age-related pulmonary dysfunction

Abadir, P., Cosarderelioglu, C., Damarla, M., Malinina, A., Dikeman, D., Marx-Rattner, R., Nader, M. M., Abadir, M., Walston, J. & Neptune, E., Feb 2024, In: Biochemical Pharmacology. 220, 115978.

Research output: Contribution to journal › Article › peer-review

2023

Angiotensin receptor blocker use is associated with upregulation of the memory-protective angiotensin type 4 receptor (AT₄R) in the postmortem brains of individuals without cognitive impairment

Cosarderelioglu, C., Nidadavolu, L. S., George, C. J., Marx-Rattner, R., Powell, L., Xue, Q. L., Tian, J., Oh, E. S., Ferrucci, L., Dincer, P., Bennett, D. A., Walston, J. D. & Abadir, P. M., Feb 2023, In: GeroScience. 45, 1, p. 371-384 14 p.

Research output: Contribution to journal › Article › peer-review

An overview of the resilience world: Proceedings of the American Geriatrics Society and National Institute on Aging State of Resilience Science Conference

Abadir, P. M., Bandeen-Roche, K., Bergeman, C., Bennett, D., Davis, D., Kind, A., LeBrasseur, N., Stern, Y., Varadhan, R. & Whitson, H. E., Aug 2023, In: Journal of the American Geriatrics Society. 71, 8, p. 2381-2392 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Associations between circulating cell-free mitochondrial DNA, inflammatory markers, and cognitive and physical outcomes in community dwelling older adults

Nidadavolu, L. S., Feger, D., Chen, D., Wu, Y., Grodstein, F., Gross, A. L., Bennett, D. A., Walston, J. D., Oh, E. S. & Abadir, P. M., Dec 2023, In: Immunity and Ageing. 20, 1, 24.

Research output: Contribution to journal › Article › peer-review

Open Access

A Study of Physical Resilience and Aging (SPRING): Conceptual framework, rationale, and study design

Walston, J., Varadhan, R., Xue, Q. L., Buta, B., Sieber, F., Oni, J., Imus, P., Crews, D. C., Artz, A., Schrack, J., Kalyani, R. R., Abadir, P., Carlson, M., Hladek, M., McAdams-DeMarco, M., Jones, R., Johnson, A., Shafi, T., Newman, A. B. & Bandeen-Roche, K., Aug 2023, In: Journal of the American Geriatrics Society. 71, 8, p. 2393-2405 13 p.

Research output: Contribution to journal › Article › peer-review

Centrally Acting ACE Inhibitor Use and Physical Performance in Older Adults

George, C. J., Hall, C. B., Weiss, E. F., Verghese, J., Neptune, E. & Abadir, P., Feb 2023, In: Journal of Frailty and Aging. 12, 2, p. 103-108 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Decoding Angiotensin Receptors: TOMAHAQ-Based Detection and Quantification of Angiotensin Type-1 and Type-2 Receptors

Cosarderelioglu, C., Kreimer, S., Plaza-Rodriguez, A. I., Iglesias, P. A., Talbot, C. C., Siragy, H. M., Carey, R. M., Ubaida-Mohien, C., O’rourke, B., Ferrucci, L., Bennett, D. A., Walston, J. & Abadir, P., Sep 19 2023, In: Journal of the American Heart Association. 12, 18, e030791.

Research output: Contribution to journal › Article › peer-review

Open Access

Evaluating genomic signatures of aging in brain tissue as it relates to Alzheimer’s disease

Lynch, M. T., Taub, M. A., Farfel, J. M., Yang, J., Abadir, P., De Jager, P. L., Grodstein, F., Bennett, D. A. & Mathias, R. A., Dec 2023, In: Scientific reports. 13, 1, 14747.

Research output: Contribution to journal › Article › peer-review

Open Access

Interleukin-6 Drives Mitochondrial Dysregulation and Accelerates Physical Decline: Insights From an Inducible Humanized IL-6 Knock-In Mouse Model

Nidadavolu, L. S., Cosarderelioglu, C., Gomez, A. M., Wu, Y., Bopp, T., Zhang, C., Nguyen, T., Marx-Rattner, R., Yang, H., Antonescu, C., Florea, L., Talbot, C. C., Smith, B., Foster, D. B., Fairman, J. E., Yenokyan, G., Chung, T., Le, A., Walston, J. D. & Abadir, P. M., Oct 1 2023, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 78, 10, p. 1740-1752 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Navigating and diagnosing cognitive frailty in research and clinical domains

Nader, M. M., Cosarderelioglu, C., Miao, E., Whitson, H., Xue, Q. L., Grodstein, F., Oh, E., Ferrucci, L., Bennett, D. A., Walston, J. D., George, C. & Abadir, P. M., Nov 2023, In: Nature Aging. 3, 11, p. 1325-1333 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The promise of AI and technology to improve quality of life and care for older adults

Directors & Advisors of the AITCs, Jun 2023, In: Nature Aging. 3, 6, p. 629-631 3 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

2022

AGS and NIA bench-to bedside conference summary: Cancer and cardiovascular disease

Mohile, S., Blaum, C. S., Abadir, P. M., Dale, W., Forman, D. E., Fung, C., Holmes, H. M., Moslehi, J., Mustian, K. M., Rich, M. W. & Whitson, H. E., Oct 2022, In: Journal of the American Geriatrics Society. 70, 10, p. 2764-2774 11 p.

Research output: Contribution to journal › Article › peer-review

Circulating Cell-Free Genomic DNA Is Associated with an Increased Risk of Dementia and with Change in Cognitive and Physical Function

Nidadavolu, L. S., Feger, D., Wu, Y., Grodstein, F., Gross, A. L., Bennett, D. A., Walston, J. D., Oh, E. S. & Abadir, P. M., 2022, In: Journal of Alzheimer's Disease. 89, 4, p. 1233-1240 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Genome-Wide Analysis in Drosophila Reveals the Genetic Basis of Variation in Age-Specific Physical Performance and Response to ACE Inhibition

Gabrawy, M. M., Khosravian, N., Morcos, G. S., Morozova, T. V., Jezek, M., Walston, J. D., Huang, W., Abadir, P. M. & Leips, J., Jan 2022, In: Genes. 13, 1, 143.

Research output: Contribution to journal › Article › peer-review

Open Access

Higher Angiotensin II Type 1 Receptor Levels and Activity in the Postmortem Brains of Older Persons with Alzheimer's Dementia

Cosarderelioglu, C., Nidadavolu, L. S., George, C. J., Marx-Rattner, R., Powell, L., Xue, Q. L., Tian, J., Salib, J., Oh, E. S., Ferrucci, L., Dincer, P., Bennett, D. A., Walston, J. D. & Abadir, P. M., Apr 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 4, p. 664-672 9 p.

Research output: Contribution to journal › Article › peer-review

Losartan Mitigates Oxidative Stress in the Brains of Aged and Inflamed IL-10^-/-Mice

Saleh, N., Cosarderelioglu, C., Vajapey, R., Walston, J. & Abadir, P. M., Sep 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 9, p. 1784-1788 5 p.

Research output: Contribution to journal › Article › peer-review

Metabolomics-Based Identification of Metabolic Dysfunction in Frailty

Westbrook, R., Zhang, C., Yang, H., Tian, J., Guo, S., Xue, Q. L., Walston, J., Le, A. & Abadir, P. M., Dec 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 12, p. 2367-2372 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Metabolomics Captures the Biological Signatures of Aging and Health Span and Identifies Pathway Targets for Intervention

Westbrook, R. & Abadir, P. M., Dec 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 12, p. 2343-2345 3 p.

Research output: Contribution to journal › Article › peer-review

Nature-inspired delivery of mitochondria-targeted angiotensin receptor blocker

Phillip, J. M., Lin, R., Cheetham, A., Stern, D., Li, Y., Wang, Y., Wang, H., Rini, D., Cui, H., Walston, J. D. & Abadir, P. M., Sep 1 2022, In: PNAS Nexus. 1, 4, pgac147.

Research output: Contribution to journal › Article › peer-review

Open Access

Serum Concentrations of Losartan Metabolites Correlate With Improved Physical Function in a Pilot Study of Prefrail Older Adults

Lee, J. L., Zhang, C., Westbrook, R., Gabrawy, M. M., Nidadavolu, L., Yang, H., Marx, R., Wu, Y., Anders, N. M., Ma, L., Bichara, M. D., Kwak, M. J., Buta, B., Khadeer, M., Yenokyan, G., Tian, J., Xue, Q. L., Siragy, H. M., Carey, R. M. & De Cabo, R. & 6 others, Ferrucci, L., Moaddel, R., Rudek, M. A., Le, A., Walston, J. D. & Abadir, P. M., Dec 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 12, p. 2356-2366 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Valsartan and sacubitril combination treatment enhances collagen production in older adult human skin cells

Marin, S., Godet, I., Nidadavolu, L. S., Tian, J., Dickinson, L. E., Walston, J. D., Gilkes, D. M. & Abadir, P. M., Aug 2022, In: Experimental Gerontology. 165, 111835.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Lactoferrin for the treatment of age-associated inflammation – A pilot study

Laskow, T., Langdon, J., Abadir, P., Xue, Q. L. & Walston, J., Mar 2021, In: Physiology International. 108, 1, p. 121-136 16 p.

Research output: Contribution to journal › Article › peer-review

Targeted deletion of interleukin-6 in a mouse model of chronic inflammation demonstrates opposing roles in aging: Benefit and harm

Ma, L., Nidadavolu, L. S., Yang, H., Langdon, J., Westbrook, R., Tsui, B. M. W., Lee, T. S., Hinson, J., Ling, S., Marx-Rattner, R., Wu, Y., Nguyen, T., Tan, J., Khadeer, M., Moaddel, R., Le, A., Walston, J. D. & Abadir, P. M., Feb 1 2021, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 76, 2, p. 211-215 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Valsartan nano-filaments alter mitochondrial energetics and promote faster healing in diabetic rat wounds

Nidadavolu, L. S., Stern, D., Lin, R., Wang, Y., Li, Y., Wu, Y., Marin, S., Antonio, M. J., Yenokyan, G., Boronina, T., Cole, R., Foster, D. B., Talbot, C. C., Jedrych, J., Smith, B., Rini, D., Le, A., Cui, H., Walston, J. D. & Abadir, P. M., Nov 1 2021, In: Wound Repair and Regeneration. 29, 6, p. 927-937 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Age, Frailty, and Impaired Wound Healing

Gould, L. J., Abadir, P. M. & Foy White-Chu, E., Jan 1 2020, Principles and Practice of Geriatric Surgery: Third Edition: With 261 Figures and 155 Tables. Springer International Publishing, p. 465-482 18 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Brain Renin–Angiotensin System at the Intersect of Physical and Cognitive Frailty

Cosarderelioglu, C., Nidadavolu, L. S., George, C. J., Oh, E. S., Bennett, D. A., Walston, J. D. & Abadir, P. M., Sep 30 2020, In: Frontiers in Neuroscience. 14, 586314.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Kynurenines link chronic inflammation to functional decline and physical frailty

Westbrook, R., Chung, T., Lovett, J., Ward, C., Joca, H., Yang, H., Khadeer, M., Tian, J., Xue, Q. L., Le, A., Ferrucci, L., Moaddel, R., de Cabo, R., Hoke, A., Walston, J. & Abadir, P. M., Aug 20 2020, In: JCI Insight. 5, 16, e136091.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Plasma levels of corticosterone, tumor necrosis factor receptor 1 and interleukin 6 are influenced by age, sex and chronic inflammation in mice treated with acute temperature stress

Ge, N., Westbrook, R., Langdon, J., Yang, H., Marx, R., Abadir, P., Xue, Q. L. & Walston, J. D., Dec 2020, In: Experimental Gerontology. 142, 111136.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Lisinopril Preserves Physical Resilience and Extends Life Span in a Genotype-Specific Manner in Drosophila melanogaster

Gabrawy, M. M., Campbell, S., Carbone, M. A., Morozova, T. V., Arya, G. H., Turlapati, L. B., Walston, J. D., Starz-Gaiano, M., Everett, L., Mackay, T. F. C., Leips, J. & Abadir, P. M., Nov 13 2019, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 12, p. 1844-1852 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

When Women Rise, We All Rise: American Geriatrics Society Position Statement on Achieving Gender Equity in Geriatrics

Boxer, R., Norman, M., Abadir, P., Beizer, J. L., Dierich, M., Lau, S., Linnebur, S. A., Lundebjerg, N. E., Naik, A. D., Schreiber, R., Unroe, K., Mikhailovich, A. L. & Goldstein, A. C., Dec 1 2019, In: Journal of the American Geriatrics Society. 67, 12, p. 2447-2454 8 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

2018

Age-and genotype-specific effects of the angiotensin-converting enzyme inhibitor lisinopril on mitochondrial and metabolic parameters in drosophila melanogaster

Ederer, K. A., Jin, K., Bouslog, S., Wang, L., Gorman, G. S., Rowe, G. C., Abadir, P., Raftery, D., Moellering, D., Promislow, D., Jumbo-Lucioni, P. & De Luca, M., Nov 2018, In: International journal of molecular sciences. 19, 11, 3351.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Report and Research Agenda of the American Geriatrics Society and National Institute on Aging Bedside-to-Bench Conference on Urinary Incontinence in Older Adults: A Translational Research Agenda for a Complex Geriatric Syndrome

the American Geriatrics Society/National Institute on Aging Urinary Incontinence Conference Planning Committee and Faculty, Apr 2018, In: Journal of the American Geriatrics Society. 66, 4, p. 773-782 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

15 Scopus citations

Topical Reformulation of Valsartan for Treatment of Chronic Diabetic Wounds

Abadir, P., Hosseini, S., Faghih, M., Ansari, A., Lay, F., Smith, B., Beselman, A., Vuong, D., Berger, A., Tian, J., Rini, D., Keenahan, K., Budman, J., Inagami, T., Fedarko, N., Marti, G., Harmon, J. & Walston, J., Feb 2018, In: Journal of Investigative Dermatology. 138, 2, p. 434-443 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

2017

Co-Localization of Macrophage Inhibitory Factor and Nix in Skeletal Muscle of the Aged Male Interleukin 10 Null Mouse

Abadir, P., Ko, F., Marx, R., Powell, L., Kieserman, E., Yang, H. & Walston, J., 2017, In: The Journal of frailty & aging. 6, 3, p. 118-121 4 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Discovery and Validation of Agonistic Angiotensin Receptor Autoantibodies as Biomarkers of Adverse Outcomes

Abadir, P. M., Jain, A., Powell, L. J., Xue, Q. L., Tian, J., Hamilton, R. G., Bennett, D. A., Finucane, T., Walston, J. D. & Fedarko, N. S., Jan 31 2017, In: Circulation. 135, 5, p. 449-459 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

2016

Impaired mitochondrial degradation by autophagy in the skeletal muscle of the aged female interleukin 10 null mouse

Ko, F., Abadir, P., Marx, R., Westbrook, R., Cooke, C., Yang, H. & Walston, J., Jan 1 2016, In: Experimental Gerontology. 73, p. 23-27 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Rapamycin increases grip strength and attenuates age-related decline in maximal running distance in old low capacity runner rats

Xue, Q. L., Yang, H., Li, H. F., Abadir, P. M., Burks, T. N., Koch, L. G., Britton, S. L., Carlson, J., Chen, L., Walston, J. D. & Leng, S. X., 2016, In: Aging. 8, 4, p. 769-776 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Peter Abadir

Research output

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