Michelle Vaz

2020

Epigenetic therapy inhibits metastases by disrupting premetastatic niches

Lu, Z., Zou, J., Li, S., Topper, M. J., Tao, Y., Zhang, H., Jiao, X., Xie, W., Kong, X., Vaz, M., Li, H., Cai, Y., Xia, L., Huang, P., Rodgers, K., Lee, B., Riemer, J. B., Day, C. P., Yen, R. W. C., Cui, Y., & 28 othersWang, Y., Wang, Y., Zhang, W., Easwaran, H., Hulbert, A., Kim, K. B., Juergens, R. A., Yang, S. C., Battafarano, R. J., Bush, E. L., Broderick, S. R., Cattaneo, S. M., Brahmer, J. R., Rudin, C. M., Wrangle, J., Mei, Y., Kim, Y. J., Zhang, B., Wang, K. K. H., Forde, P. M., Margolick, J. B., Nelkin, B. D., Zahnow, C. A., Pardoll, D. M., Housseau, F., Baylin, S. B., Shen, L. & Brock, M. V., Mar 12 2020, In: Nature. 579, 7798, p. 284-290 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

2018

FOSL1 promotes Kras-induced lung cancer through amphiregulin and cell survival gene regulation

Elangovan, I. M., Vaz, M., Tamatam, C. R., Potteti, H. R., Reddy, N. M. & Reddy, S. P., May 1 2018, In: American journal of respiratory cell and molecular biology. 58, 5, p. 625-635 11 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2017

Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations

Vaz, M., Hwang, S. Y., Kagiampakis, I., Phallen, J., Patil, A., O'Hagan, H. M., Murphy, L., Zahnow, C. A., Gabrielson, E., Velculescu, V. E., Easwaran, H. P. & Baylin, S. B., Sep 11 2017, In: Cancer cell. 32, 3, p. 360-376.e6

Research output: Contribution to journal › Article › peer-review

Open Access

87 Scopus citations

Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

Topper, M. J., Vaz, M., Chiappinelli, K. B., DeStefano Shields, C. E., Niknafs, N., Yen, R. W. C., Wenzel, A., Hicks, J., Ballew, M., Stone, M., Tran, P. T., Zahnow, C. A., Hellmann, M. D., Anagnostou, V., Strissel, P. L., Strick, R., Velculescu, V. E. & Baylin, S. B., Nov 30 2017, In: Cell. 171, 6, p. 1284-1300.e21

Research output: Contribution to journal › Article › peer-review

Open Access

153 Scopus citations

2015

Myeloid-specific Fos-related antigen-1 regulates cigarette smoke - Induced lung inflammation, not emphysema, in mice

Vaz, M., Rajasekaran, S., Potteti, H. R. & Reddy, S. P., Jul 1 2015, In: American journal of respiratory cell and molecular biology. 53, 1, p. 125-134 10 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2012

Fra-1/AP-1 transcription factor negatively regulates pulmonary fibrosis in vivo

Rajasekaran, S., Vaz, M. & Reddy, S. P., Jul 24 2012, In: PloS one. 7, 7, e41611.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Genetic disruption of fra-1 decreases susceptibility to endotoxin-induced acute lung injury and mortality in mice

Vaz, M., Reddy, N. M., Rajasekaran, S., Reddy, S. P. & Subbiah, R., Jan 1 2012, In: American journal of respiratory cell and molecular biology. 46, 1, p. 55-62 8 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Oxidant-induced cell death and Nrf2-dependent antioxidative response are controlled by Fra-1/AP-1

Vaz, M., Machireddy, N., Irving, A., Potteti, H. R., Chevalier, K., Kalvakolanu, D. & Reddy, S. P., May 2012, In: Molecular and cellular biology. 32, 9, p. 1694-1709 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

The transcription factor encyclopedia.

Yusuf, D., Butland, S. L., Swanson, M. I., Bolotin, E., Ticoll, A., Cheung, W. A., Zhang, X. Y. C., Dickman, C. T. D., Fulton, D. L., Lim, J. S., Schnabl, J. M., Ramos, O. H. P., Vasseur-Cognet, M., de Leeuw, C. N., Simpson, E. M., Ryffel, G. U., Lam, E. W. F., Kist, R., Wilson, M. S. C., Marco-Ferreres, R., & 79 othersBrosens, J. J., Beccari, L. L., Bovolenta, P., Benayoun, B. A., Monteiro, L. J., Schwenen, H. D. C., Grontved, L., Wederell, E., Mandrup, S., Veitia, R. A., Chakravarthy, H., Hoodless, P. A., Mancarelli, M. M., Torbett, B. E., Banham, A. H., Reddy, S. P., Cullum, R. L., Liedtke, M., Tschan, M. P., Vaz, M., Rizzino, A., Zannini, M., Frietze, S., Farnham, P. J., Eijkelenboom, A., Brown, P. J., Laperrière, D., Leprince, D., de Cristofaro, T., Prince, K. L., Putker, M., del Peso, L., Camenisch, G., Wenger, R. H., Mikula, M., Rozendaal, M., Mader, S., Ostrowski, J., Rhodes, S. J., Van Rechem, C., Boulay, G., Olechnowicz, S. W. Z., Breslin, M. B., Lan, M. S., Nanan, K. K., Wegner, M., Hou, J., Mullen, R. D., Colvin, S. C., Noy, P. J., Webb, C. F., Witek, M. E., Ferrell, S., Daniel, J. M., Park, J., Waldman, S. A., Peet, D. J., Taggart, M., Jayaraman, P. S., Karrich, J. J., Blom, B., Vesuna, F., O'Geen, H., Sun, Y., Gronostajski, R. M., Woodcroft, M. W., Hough, M. R., Chen, E., Europe-Finner, G. N., Karolczak-Bayatti, M., Bailey, J., Hankinson, O., Raman, V., LeBrun, D. P., Biswal, S., Harvey, C. J., DeBruyne, J. P., Hogenesch, J. B. & Hevner, R. F., 2012, In: Genome biology. 13, 3, p. R24

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

2008

A Fra-1-dependent, matrix metalloproteinase driven EGFR activation promotes human lung epithelial cell motility and invasion

Adiseshaiah, P., Vaz, M., Machireddy, N., Kalvakolanu, D. V. & Reddy, S. P., Aug 2008, In: Journal of Cellular Physiology. 216, 2, p. 405-412 8 p.

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

ERK signaling regulates tumor promoter induced c-Jun recruitment at the Fra-1 promoter

Adiseshaiah, P., Li, J., Vaz, M., Kalvakolanu, D. V. & Reddy, S. P., Jun 27 2008, In: Biochemical and Biophysical Research Communications. 371, 2, p. 304-308 5 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Michelle Vaz

Research output

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