Laura Sena

2024

Association of PARP inhibitor treatment on the prevalence and progression of clonal hematopoiesis in patients with advanced prostate cancer

Marshall, C. H., Gondek, L. P., Daniels, V., Lu, C., Pasca, S., Xie, J., Markowski, M. C., Paller, C. J., Sena, L. A., Denmeade, S. R., Luo, J. & Antonarakis, E., Jul 2024, In: Prostate. 84, 10, p. 954-958 5 p.

Research output: Contribution to journal › Article › peer-review

Bipolar androgen therapy plus nivolumab for patients with metastatic castration-resistant prostate cancer: the COMBAT phase II trial

Markowski, M. C., Taplin, M. E., Aggarwal, R., Sena, L. A., Wang, H., Qi, H., Lalji, A., Sinibaldi, V., Carducci, M. A., Paller, C. J., Marshall, C. H., Eisenberger, M., Sanin, D. E., Yegnasubramanian, S., Gomes-Alexandre, C., Ozbek, B., Jones, T., De Marzo, A. M., Denmeade, S. R. & Antonarakis, E. S., Dec 2024, In: Nature communications. 15, 1, 14.

Research output: Contribution to journal › Article › peer-review

Open Access

Divergent immune microenvironments in two tumor nodules from a patient with mismatch repair-deficient prostate cancer

Bergom, H. E., Sena, L. A., Day, A., Miller, B., Miller, C. D., Lozada, J. R., Zorko, N., Wang, J., Shenderov, E., Lobo, F. P., Caramella-Pereira, F., Marchionni, L., Drake, C. G., Lotan, T., De Marzo, A. M., Hwang, J. & Antonarakis, E. S., Dec 2024, In: npj Genomic Medicine. 9, 1, 7.

Research output: Contribution to journal › Article › peer-review

Open Access

Intratumoral heterogeneity drives acquired therapy resistance in a patient with metastatic prostate cancer

Rhinehart, D. P., Lai, J., Sanin, D. E., Vakkala, V., Mendes, A., Bailey, C., Antonarakis, E., Paller, C. J., Wu, X., Lotan, T. L., Karchin, R. & Sena, L. A., Dec 2024, In: npj Precision Oncology. 8, 1, 275.

Research output: Contribution to journal › Article › peer-review

Open Access

Metabolic Reprogramming of Tumor-Associated Macrophages Using Glutamine Antagonist JHU083 Drives Tumor Immunity in Myeloid-Rich Prostate and Bladder Cancers

Praharaj, M., Shen, F., Lee, A. J., Zhao, L., Nirschl, T. R., Theodros, D., Singh, A. K., Wang, X., Adusei, K. M., Lombardo, K. A., Williams, R. A., Sena, L. A., Thompson, E. A., Tam, A., Yegnasubramanian, S., Pearce, E. J., Leone, B., Alt, J., Rais, R. & Slusher, B. S. & 3 others, Pardoll, D. M., Powell, J. & Zarif, J. C., Jul 1 2024, In: Cancer Immunology Research. 12, 7, p. 854-875 22 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

MLH1 Loss in Primary Prostate Cancer

Abadchi, S. N., Sena, L. A., Antonarakis, E., Pritchard, C. C., Eshleman, J. R., Konnick, E. Q., Salipante, S. J., Shenderov, E. & Lotan, T. L., 2023, In: JCO Precision Oncology. 7, e2200611.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC

Sena, L. A., Kumar, R., Sanin, D. E., Thompson, E. A., Rosen, D. M., Dalrymple, S. L., Antony, L., Yang, Y., Gomes-Alexandre, C., Hicks, J. L., Jones, T., Bowers, K. A., Eskra, J. N., Meyers, J., Gupta, A., Skaist, A., Yegnasubramanian, S., Luo, J., Brennen, W. N. & Kachhap, S. K. & 5 others, Antonarakis, E. S., De Marzo, A. M., Isaacs, J. T., Markowski, M. C. & Denmeade, S. R., Dec 1 2022, In: Journal of Clinical Investigation. 132, 23, e162396.

Research output: Contribution to journal › Article › peer-review

Open Access

Forming the Hematology-Oncology Collaborative Videoconferencing (CO-VID) Learning Initiative: Experiential Lessons Learned From a Novel Trainee-Led Multidisciplinary Virtual Learning Platform

Martin, R. L., Grant, M. J., Kimani, S., Midha, S., May, J., Patell, R., Collier, E., Furfaro, D., Bodine, C., Reap, L., Shah, N., DeLaune, J., Brusca, S., Olazagasti, C., Goyal, S., Rubinstein, S., Hakim, N., Qin, S., Browning, S. L. & Sena, L. & 11 others, Gilbert, J., Davidson, M., Lovly, C. M., Seetharamu, N., Rangachari, D., Murphy, M., Chatwal, M., Paschal, R., Henry, E., Collichio, F. & Green, J. R., Jan 1 2022, In: JCO Oncology Practice. 18, 2, p. E36-E46

Research output: Contribution to journal › Article › peer-review

Open Access

Molecular and Clinical Characterization of Patients With Metastatic Castration Resistant Prostate Cancer Achieving Deep Responses to Bipolar Androgen Therapy

Markowski, M. C., Kachhap, S., De Marzo, A. M., Sena, L. A., Luo, J., Denmeade, S. R. & Antonarakis, E. S., Apr 2022, In: Clinical Genitourinary Cancer. 20, 2, p. 97-101 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Trainee-Led Quality Improvement Project to Improve Fertility Preservation Counseling for Patients With Cancer

Sena, L. A., Sedhom, R., Scott, S., Kagan, A., Marple, A. H., Canzoniero, J. V., Hsu, M., Hussaini, S. M. Q., Herati, A. S., Reschke, L., Antero, M. F., Christianson, M. S., Binder, A. F., Chen, A. R., Donehower, R. C., Marrone, K. A. & Gupta, A., Mar 1 2022, In: JCO Oncology Practice. 18, 3, p. E403-E411

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Bipolar androgen therapy sensitizes castration-resistant prostate cancer to subsequent androgen receptor ablative therapy

Sena, L. A., Wang, H., Lim ScM, S. J., Rifkind, I., Ngomba, N., Isaacs, J. T., Luo, J., Pratz, C., Sinibaldi, V., Carducci, M. A., Paller, C. J., Eisenberger, M., Markowski, M. C., Antonarakis, E. & Denmeade, S. R., Feb 2021, In: European Journal of Cancer. 144, p. 302-309 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Mismatch repair-deficient prostate cancer with parenchymal brain metastases treated with immune checkpoint blockade

Sena, L. A., Salles, D. C., Engle, E. L., Zhu, Q., Tukachinsky, H., Lotan, T. L. & Antonarakis, E. S., Aug 2021, In: Cold Spring Harbor Molecular Case Studies. 7, 4

Research output: Contribution to journal › Article › peer-review

Open Access

Mitochondrial metabolism is essential for invariant natural killer T cell development and function

Weng, X., Kumar, A., Cao, L., He, Y., Morgun, E., Visvabharathy, L., Zhao, J., Sena, L. A., Weinberg, S. E., Chandel, N. S. & Wang, C. R., Mar 30 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 13, e2021385118.

Research output: Contribution to journal › Article › peer-review

Open Access

Tumor Frameshift Mutation Proportion Predicts Response to Immunotherapy in Mismatch Repair-Deficient Prostate Cancer

Sena, L. A., Fountain, J., Isaacsson Velho, P., Lim, S. J., Wang, H., Nizialek, E., Rathi, N., Nussenzveig, R., Maughan, B. L., Velez, M. G., Ashkar, R., Larson, A. C., Pritchard, C. C., Adra, N., Bryce, A. H., Agarwal, N., Pardoll, D. M., Eshleman, J. R., Lotan, T. L. & Antonarakis, E., Feb 2021, In: Oncologist. 26, 2, p. e270-e278

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2019

Mitochondrial complex III is essential for suppressive function of regulatory T cells

Weinberg, S. E., Singer, B. D., Steinert, E. M., Martinez, C. A., Mehta, M. M., Martínez-Reyes, I., Gao, P., Helmin, K. A., Abdala-Valencia, H., Sena, L. A., Schumacker, P. T., Turka, L. A. & Chandel, N. S., Jan 24 2019, In: Nature. 565, 7740, p. 495-499 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2017

The plot thickens

Fleming, R. C., Sena, L. A., Manesh, R., Huff, C. A. & Aronowitz, P. B., Jul 2017, In: Journal of Hospital Medicine. 12, 7, p. 575-579 5 p.

Research output: Contribution to journal › Article › peer-review

2014

Targeting SOD1 reduces experimental non-small-cell lung cancer

Glasauer, A., Sena, L. A., Diebold, L. P., Mazar, A. P. & Chandel, N. S., Jan 2 2014, In: Journal of Clinical Investigation. 124, 1, p. 117-128 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2013

Circadian clock NAD⁺ cycle drives mitochondrial oxidative metabolism in mice

Peek, C. B., Affinati, A. H., Ramsey, K. M., Kuo, H. Y., Yu, W., Sena, L. A., Ilkayeva, O., Marcheva, B., Kobayashi, Y., Omura, C., Levine, D. C., Bacsik, D. J., Gius, D., Newgard, C. B., Goetzman, E., Chandel, N. S., Denu, J. M., Mrksich, M. & Bass, J., 2013, In: Science. 342, 6158, 1243417.

Research output: Contribution to journal › Article › peer-review

Open Access

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

Sena, L. A., Li, S., Jairaman, A., Prakriya, M., Ezponda, T., Hildeman, D. A., Wang, C. R., Schumacker, P. T., Licht, J. D., Perlman, H., Bryce, P. J. & Chandel, N. S., Feb 21 2013, In: Immunity. 38, 2, p. 225-236 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Laura Sena

Research output

Search results