John Isaacs

2024

Targeting the fibroblast growth factor pathway in molecular subtypes of castration-resistant prostate cancer

Labrecque, M. P., Brown, L. G., Coleman, I. M., Nguyen, H. M., Dalrymple, S., Brennen, W. N., Isaacs, J. T., Li, D., Lakely, B., DeLucia, D. C., Lee, J. K., Schweizer, M. T., Lin, D. W., Corey, E., Nelson, P. S. & Morrissey, C., Jan 2024, In: Prostate. 84, 1, p. 100-110 11 p.

Research output: Contribution to journal › Article › peer-review

2023

Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling

Patterson, J. C., Varkaris, A., Croucher, P. J. P., Ridinger, M., Dalrymple, S., Nouri, M., Xie, F., Varmeh, S., Jonas, O., Whitman, M. A., Chen, S., Rashed, S., Makusha, L., Luo, J., Isaacs, J. T., Erlander, M. G., Einstein, D. J., Balk, S. P. & Yaffe, M. B., Jan 15 2023, In: Cancer Research. 83, 2, p. 219-238 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The future of patient-derived xenografts in prostate cancer research

Lawrence, M. G., Taylor, R. A., Cuffe, G. B., Ang, L. S., Clark, A. K., Goode, D. L., Porter, L. H., Le Magnen, C., Navone, N. M., Schalken, J. A., Wang, Y., van Weerden, W. M., Corey, E., Isaacs, J. T., Nelson, P. S. & Risbridger, G. P., Jun 2023, In: Nature Reviews Urology. 20, 6, p. 371-384 14 p.

Research output: Contribution to journal › Article › peer-review

Third generation quinoline-3-carboxamide transcriptional disrupter of HDAC4, HIF-1α, and MEF-2 signaling for metastatic castration-resistant prostate cancer

Isaacs, J. T., Dalrymple, S. L., Antony, L., Marc Rosen, D., Coleman, I. M., Nelson, P. S., Kostova, M., Murray, I. A., Perdew, G. H., Denmeade, S. R., Akinboye, E. S. & Brennen, W. N., Nov 2023, In: Prostate. 83, 15, p. 1470-1493 24 p.

Research output: Contribution to journal › Article › peer-review

2022

Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC

Sena, L. A., Kumar, R., Sanin, D. E., Thompson, E. A., Rosen, D. M., Dalrymple, S. L., Antony, L., Yang, Y., Gomes-Alexandre, C., Hicks, J. L., Jones, T., Bowers, K. A., Eskra, J. N., Meyers, J., Gupta, A., Skaist, A., Yegnasubramanian, S., Luo, J., Brennen, W. N., Kachhap, S. K., & 5 othersAntonarakis, E. S., De Marzo, A. M., Isaacs, J. T., Markowski, M. C. & Denmeade, S. R., Dec 1 2022, In: Journal of Clinical Investigation. 132, 23, e162396.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Bipolar androgen therapy sensitizes castration-resistant prostate cancer to subsequent androgen receptor ablative therapy

Sena, L. A., Wang, H., Lim ScM, S. J., Rifkind, I., Ngomba, N., Isaacs, J. T., Luo, J., Pratz, C., Sinibaldi, V., Carducci, M. A., Paller, C. J., Eisenberger, M. A., Markowski, M. C., Antonarakis, E. S. & Denmeade, S. R., Feb 2021, In: European Journal of Cancer. 144, p. 302-309 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Overcoming stromal barriers to immuno-oncological responses via fibroblast activation protein-targeted therapy

Brennen, W. N., J Thorek, D. L., Jiang, W., Krueger, T. E., Antony, L., Denmeade, S. R. & Isaacs, J. T., Feb 2021, In: Immunotherapy. 13, 2, p. 155-175 21 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer

Brennen, W. N., Zhu, Y., Coleman, I. M., Dalrymple, S. L., Antony, L., Patel, R. A., Hanratty, B., Chikarmane, R., Meeker, A. K., Zheng, S. L., Hooper, J. E., Luo, J., de Marzo, A. M., Corey, E., Xu, J., Yegnasubramanian, S., Haffner, M. C., Nelson, P. S., Nelson, W. G., Isaacs, W. B., & 1 othersIsaacs, J. T., Apr 1 2021, In: JCI Insight. 6, 8, e146827.

Research output: Contribution to journal › Article › peer-review

Open Access

Supraphysiologic Testosterone Induces Ferroptosis and Activates Immune Pathways through Nucleophagy in Prostate Cancer

Kumar, R., Mendonca, J., Owoyemi, O., Boyapati, K., Thomas, N., Kanacharoen, S., Coffey, M., Topiwala, D., Gomes, C., Ozbek, B., Jones, T., Rosen, M., Dong, L., Wiens, S., Brennen, W. N., Isaacs, J. T., Marzo, A. M. D., Markowski, M. C., Antonarakis, E. S., Qian, D. Z., & 5 othersPienta, K. J., Pardoll, D. M., Carducci, M. A., Denmeade, S. R. & Kachhap, S. K., Dec 1 2021, In: Cancer Research. 81, 23, p. 5948-5962 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress

Nyquist, M. D., Corella, A., Coleman, I., De Sarkar, N., Kaipainen, A., Ha, G., Gulati, R., Ang, L., Chatterjee, P., Lucas, J., Pritchard, C., Risbridger, G., Isaacs, J., Montgomery, B., Morrissey, C., Corey, E. & Nelson, P. S., May 26 2020, In: Cell Reports. 31, 8, 107669.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Microparticle encapsulation of a prostate-targeted biologic for the treatment of liver metastases in a preclinical model of castration-resistant prostate cancer

Rogers, O. C., Antony, L., Levy, O., Joshi, N., Simons, B. W., Dalrymple, S. L., Rosen, D. M., Pickering, A., Lan, H., Kuang, H., Ranganath, S. H., Zheng, L., Karp, J. M., Howard, S. P., Denmeade, S. R., Isaacs, J. T. & Brennen, W. N., Nov 1 2020, In: Molecular cancer therapeutics. 19, 11, p. 2353-2362 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors

Zhu, Y., Dalrymple, S. L., Coleman, I., Zheng, S. L., Xu, J., Hooper, J. E., Antonarakis, E. S., De Marzo, A. M., Meeker, A. K., Nelson, P. S., Isaacs, W. B., Denmeade, S. R., Luo, J., Brennen, W. N. & Isaacs, J. T., Nov 5 2020, In: Oncogene. 39, 45, p. 6935-6949 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2019

A Phase I Study to Assess the Safety and Cancer-Homing Ability of Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells in Men with Localized Prostate Cancer

Schweizer, M. T., Wang, H., Bivalacqua, T. J., Partin, A. W., Lim, S. J., Chapman, C., Abdallah, R., Levy, O., Bhowmick, N. A., Karp, J. M., De Marzo, A., Isaacs, J. T., Brennen, W. N. & Denmeade, S. R., May 2019, In: Stem Cells Translational Medicine. 8, 5, p. 441-449 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Asporin restricts mesenchymal stromal cell differentiation, alters the tumor microenvironment, and drives metastatic progression

Hughes, R. M., Simons, B. W., Khan, H., Miller, R., Kugler, V., Torquato, S., Theodros, D., Haffner, M. C., Lotan, T., Huang, J., Davicioni, E., An, S. S., Riddle, R. C., Thorek, D. L. J., Garraway, I. P., Fertig, E. J., Isaacs, J. T., Nathaniel Brennen, W., Park, B. H. & Hurley, P. J., 2019, In: Cancer Research. 79, 14, p. 3636-3650 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Establishing a cryopreservation protocol for patient-derived xenografts of prostate cancer

Porter, L. H., Lawrence, M. G., Wang, H., Clark, A. K., Bakshi, A., Obinata, D., Goode, D., Papargiris, M., Mural, Clouston, D., Ryan, A., Norden, S., Corey, E., Nelson, P. S., Isaacs, J. T., Grummet, J., Kourambas, J., Sandhu, S., Murphy, D. G., Pook, D., & 3 othersFrydenberg, M., Taylor, R. A. & Risbridger, G. P., Aug 1 2019, In: Prostate. 79, 11, p. 1326-1337 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Tumor-infiltrating mesenchymal stem cells: Drivers of the immunosuppressive tumor microenvironment in prostate cancer?

Krueger, T. E., Thorek, D. L. J., Meeker, A. K., Isaacs, J. T. & Brennen, W. N., Feb 15 2019, In: Prostate. 79, 3, p. 320-330 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

2018

2-fluoro-5-maleimidobenzoic acid-linked albumin drug (MAD) delivery for selective systemic targeting of metastatic prostate cancer

Akinboye, E., Rogers, O. C. & Isaacs, J. T., Jun 15 2018, In: Prostate. 78, 9, p. 655-663 9 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient-derived xenograft (PDX) models

Navone, N. M., van Weerden, W. M., Vessella, R. L., Williams, E. D., Wang, Y., Isaacs, J. T., Nguyen, H. M., Culig, Z., van der Pluijm, G., Rentsch, C. A., Marques, R. B., de Ridder, C. M. A., Bubendorf, L., Thalmann, G. N., Brennen, W. N., Santer, F. R., Moser, P. L., Shepherd, P., Efstathiou, E., Xue, H., & 11 othersLin, D., Buijs, J., Bosse, T., Collins, A., Maitland, N., Buzza, M., Kouspou, M., Achtman, A., Taylor, R. A., Risbridger, G. & Corey, E., Dec 1 2018, In: Prostate. 78, 16, p. 1262-1282 21 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

2017

Low p16^INK4a Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone

Graham, M. K., Principessa, L., Antony, L., Meeker, A. K. & Isaacs, J. T., Mar 1 2017, In: Prostate. 77, 4, p. 374-384 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate

Brennen, W. N., Zhang, B., Kulac, I., Kisteman, L. N., Antony, L., Wang, H., Meeker, A. K., De Marzo, A. M., Garraway, I. P., Denmeade, S. R. & Isaacs, J. T., 2017, In: Oncotarget. 8, 29, p. 46710-46727 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

2016

Analytic validation of RNA in situ hybridization (RISH) for AR and AR-V7 expression in human prostate cancer

Guedes, L. B., Morais, C. L., Almutairi, F., Haffner, M. C., Zheng, Q., Isaacs, J. T., Antonarakis, E. S., Lu, C., Tsai, H., Luo, J., De Marzo, A. M. & Lotan, T. L., Sep 15 2016, In: Clinical Cancer Research. 22, 18, p. 4651-4663 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Androgen deprivation followed by acute androgen stimulation selectively sensitizes AR-positive prostate cancer cells to ionizing radiation

Hedayati, M., Haffner, M. C., Coulter, J. B., Raval, R. R., Zhang, Y., Zhou, H., Mian, O., Knight, E. J., Razavi, N., Dalrymple, S., Isaacs, J. T., Santos, A., Hales, R., Nelson, W. G., Yegnasubramanian, S. & DeWeese, T. L., Jul 1 2016, In: Clinical Cancer Research. 22, 13, p. 3310-3319 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

A prodrug-doped cellular Trojan Horse for the potential treatment of prostate cancer

Levy, O., Brennen, W. N., Han, E., Rosen, D. M., Musabeyezu, J., Safaee, H., Ranganath, S., Ngai, J., Heinelt, M., Milton, Y., Wang, H., Bhagchandani, S. H., Joshi, N., Bhowmick, N., Denmeade, S. R., Isaacs, J. T. & Karp, J. M., Jun 1 2016, In: Biomaterials. 91, p. 140-150 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Assessing angiogenic responses induced by primary human prostate stromal cells in a three-dimensional fibrin matrix assay

Brennen, W. N., Nguyen, H., Dalrymple, S. L., Reppert-Gerber, S., Kim, J., Isaacs, J. T. & Hammers, H., 2016, In: Oncotarget. 7, 44, p. 71298-71308 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Rapid selection of mesenchymal stem and progenitor cells in primary prostate stromal cultures

Brennen, W. N., Kisteman, L. N. & Isaacs, J. T., May 1 2016, In: Prostate. 76, 6, p. 552-564 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

2015

Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: Results from a pilot clinical study

Schweizer, M. T., Antonarakis, E. S., Wang, H., Seun Ajiboye, A., Spitz, A., Cao, H., Luo, J., Haffner, M. C., Yegnasubramanian, S., Carducci, M. A., Eisenberger, M. A., Isaacs, J. T. & Denmeade, S. R., Jan 7 2015, In: Science translational medicine. 7, 269, 269ra2.

Research output: Contribution to journal › Article › peer-review

Open Access

134 Scopus citations

2014

4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-1, 2-dihydroquinoline-3-carboxamide

Akinboye, E. S., Butcher, R. J., Yildirim, S. O. & Isaacs, J. T., Mar 2014, In: Acta Crystallographica Section E: Structure Reports Online. 70, 3, p. o297-o298

Research output: Contribution to journal › Article › peer-review

Open Access

Androgen receptor (AR) suppresses normal human prostate epithelial cell proliferation via AR/β-catenin/TCF-4 complex inhibition of c-MYC transcription

Antony, L., Van Der Schoor, F., Dalrymple, S. L. & Isaacs, J. T., Aug 2014, In: Prostate. 74, 11, p. 1118-1131 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Androgen withdrawal fails to induce detectable tissue hypoxia in the rat prostate

Regter, S., Hedayati, M., Zhang, Y., Zhou, H., Dalrymple, S., Koch, C. J., Isaacs, J. T. & Deweese, T. L., Jun 2014, In: Prostate. 74, 8, p. 805-810 6 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Anti-cancer potency of tasquinimod is enhanced via albumin-binding facilitating increased uptake in the tumor microenvironment

Isaacs, J. T., Dalrymple, S. L., Marc Rosen, D., Hammers, H., Olsson, A. & Leanderson, T., 2014, In: Oncotarget. 5, 18, p. 8093-8106 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer

Antonarakis, E. S., Lu, C., Wang, H., Luber, B., Nakazawa, M., Roeser, J. C., Chen, Y., Mohammad, T. A., Chen, Y., Fedor, H. L., Lotan, T. L., Zheng, Q., De Marzo, A. M., Isaacs, J. T., Isaacs, W. B., Nadal, R., Paller, C. J., Denmeade, S. R., Carducci, M. A., Eisenberger, M. A., & 1 othersLuo, J., Sep 11 2014, In: New England Journal of Medicine. 371, 11, p. 1028-1038 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1594 Scopus citations

Conversion of androgen receptor signaling from a growth suppressor in normal prostate epithelial cells to an oncogene in prostate cancer cells involves a gain of function in c-Myc regulation

Vander Griend, D. J., Litvinov, I. V. & Isaacs, J. T., Jun 10 2014, In: International Journal of Biological Sciences. 10, 6, p. 627-642 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

52 Scopus citations

Pharmacokinetics and toxicology of a fibroblast activation protein (FAP)-Activated prodrug in murine xenograft models of human cancer

Brennen, W. N., Rosen, D. M., Chaux, A., Netto, G. J., Isaacs, J. T. & Denmeade, S. R., Sep 2014, In: Prostate. 74, 13, p. 1308-1319 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

2013

Of mice and men-warning: Intact versus castrated adult male mice as xenograft hosts are equivalent to hypogonadal versus abiraterone treated aging human males, respectively

Michiel Sedelaar, J. P., Dalrymple, S. S. & Isaacs, J. T., Sep 2013, In: Prostate. 73, 12, p. 1316-1325 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Quantification of Mesenchymal Stem Cells (MSCs) at sites of human prostate cancer

Brennen, W. N., Chen, S., Denmeade, S. R. & Isaacs, J. T., 2013, In: Oncotarget. 4, 1, p. 106-117 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

57 Scopus citations

Tasquinimod is an allosteric modulator of HDAC4 survival signaling within the compromised cancer microenvironment

Isaacs, J. T., Antony, L., Dalrymple, S. L., Brennen, W. N., Gerber, S., Hammers, H., Wissing, M., Kachhap, S., Luo, J., Xing, L., Bjork, P., Olsson, A., Bjork, A. & Leanderson, T., Jan 15 2013, In: Cancer Research. 73, 4, p. 1386-1399 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

60 Scopus citations

2012

Adaptive auto-regulation of androgen receptor provides a paradigm shifting rationale for bipolar androgen therapy (BAT) for castrate resistant human prostate cancer

Isaacs, J. T., D'Antonio, J. M., Chen, S., Antony, L., Dalrymple, S. P., Ndikuyeze, G. H., Luo, J. & Denmeade, S. R., Oct 1 2012, In: Prostate. 72, 14, p. 1491-1505 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy

Denmeade, S. R., Mhaka, A. M., Rosen, D. M., Brennen, W. N., Dalrymple, S., Dach, I., Olesen, C., Gurel, B., DeMarzo, A. M., Wilding, G., Carducci, M. A., Dionne, C. A., Møller, J. V., Nissen, P., Christensen, S. B. & Isaacs, J. T., Jun 27 2012, In: Science translational medicine. 4, 140, 140ra86.

Research output: Contribution to journal › Article › peer-review

Open Access

116 Scopus citations

Human prostate cancer initiating cells isolated directly from localized cancer do not form prostaspheres in primary culture

Chen, S., Principessa, L. & Isaacs, J. T., Sep 15 2012, In: Prostate. 72, 13, p. 1478-1489 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug

Brennen, W. N., Rosen, D. M., Wang, H., Isaacs, J. T. & Denmeade, S. R., Sep 5 2012, In: Journal of the National Cancer Institute. 104, 17, p. 1320-1334 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

123 Scopus citations

Tasquinimod prevents the angiogenic rebound induced by fractionated radiation resulting in an enhanced therapeutic response of prostate cancer xenografts

Dalrymple, S. L., Becker, R. E., Zhou, H., Deweese, T. L. & Isaacs, J. T., May 1 2012, In: Prostate. 72, 6, p. 638-648 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

2011

Enzymatically active prostate-specific antigen promotes growth of human prostate cancers

Williams, S. A., Jelinek, C. A., Litvinov, I., Cotter, R. J., Isaacs, J. T. & Denmeade, S. R., Nov 2011, In: Prostate. 71, 15, p. 1595-1607 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

The "infectious" nature of human prostate cancer: A cautionary note

Sfanos, K. S. & Isaacs, J. T., 2011, In: Oncotarget. 2, 4, p. 281-283 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2010

Cell-autonomous intracellular androgen receptor signaling drives the growth of human prostate cancer initiating cells

Vander Griend, D. J., D'Antonio, J., Gurel, B., Antony, L., DeMarzo, A. M. & Isaacs, J. T., Jan 1 2010, In: Prostate. 70, 1, p. 90-99 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling

D'Antonio, J. M., van der Griend, D. J., Antony, L., Ndikuyeze, G., Dalrymple, S. L., Koochekpour, S. & Isaacs, J. T., 2010, In: PloS one. 5, 7, e11475.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Prostate-specific antigen (PSA) is activated by KLK2 in prostate cancer ex vivo models and in prostate-targeted PSA/KLK2 double transgenic mice

Williams, S. A., Xu, Y., De Marzo, A. M., Isaacs, J. T. & Denmeade, S. R., May 15 2010, In: Prostate. 70, 7, p. 788-796 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors

Olsson, A., Björk, A., Vallon-Christersson, J., Isaacs, J. T. & Leanderson, T., May 17 2010, In: Molecular Cancer. 9, 107.

Research output: Contribution to journal › Article › peer-review

Open Access

70 Scopus citations

2009

Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells

Vander Griend, D. J., Antony, L., Dalrymple, S. L., Xu, Y., Christensen, S. B., Denmeade, S. R. & Isaacs, J. T., May 1 2009, In: Molecular cancer therapeutics. 8, 5, p. 1340-1349 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Detection and quantification of the evolution dynamics of apoptosis using the PET voltage sensor¹⁸F-fluorobenzyl triphenyl phosphonium

Madar, I., Huang, Y., Ravert, H., Dalrymple, S. L., Davidson, N. E., Isaacs, J. T., Dannals, R. F. & Frost, J. J., May 1 2009, In: Journal of Nuclear Medicine. 50, 5, p. 774-780 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Dual-label centromere and telomere FISH identifies human, rat, and mouse cell contribution to multispecies recombinant urogenital sinus xenografts

Vander Griend, D. J., Konishi, Y., De Marzo, A. M., Isaacs, J. T. & Meeker, A. K., Oct 1 2009, In: Prostate. 69, 14, p. 1557-1564 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

John Isaacs

Research output

Search results